Clin Psychopharmacol Neurosci.  2015 Apr;13(1):113-114. 10.9758/cpn.2015.13.1.113.

Olanzapine-induced Orthostatic Hypotension

  • 1Department of Psychiatry, KPC Medical College and Hospital, Kolkata, West Bengal, India.
  • 2Department of Psychiatry, Kasturba Medical College, Manipal, Karnataka, India.


Olanzapine is an atypical antipsychotic which is efficacious in the treatment of schizophrenia. The adverse effect profile for olanzapine is benign except for higher rates of metabolic events. Orthostatic hypotension is less commonly reported with olanzapine as compared to first-generation and few atypical antipsychotics. We report a case where olanzapine, in a dose dependent fashion, caused transient postural hypotension.


Olanzapine; Antipsychotics; Orthostatic hypotension
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