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Transcriptional Network Controlling Endochondral Ossification

Hata K, Takahata Y, Murakami T, Nishimura

Endochondral ossification is the fundamental process of skeletal development in vertebrates. Chondrocytes undergo sequential steps of differentiation, including mesenchymal condensation, proliferation, hypertrophy, and mineralization. These steps, which are required for...
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Regulation of Cartilage Development and Diseases by Transcription Factors

Nishimura , Hata K, Takahata Y, Murakami T, Nakamura E, Yagi H

Genetic studies and molecular cloning approaches have been successfully used to identify several transcription factors that regulate the numerous stages of cartilage development. Sex-determining region Y (SRY)-box 9 (Sox9) is...
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Clinical Usefulness of Dual Red Imaging in Gastric Endoscopic Submucosal Dissection: A Pilot Study

Yorita N, Oka S, Tanaka S, Kotachi T, Nagasaki N, Hata K, Kuroki K, Masuda K, Kurihara M, Kiso M, Boda T, Ito M, Chayama K

Background/Aims: Dual red imaging (DRI) is a new, image-enhanced endoscopy technique. There are few reports about the usefulness of DRI during gastric endoscopic submucosal dissection (ESD). We aimed to examine...
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Risk factors for non-reaching of ileal pouch to the anus in laparoscopic restorative proctocolectomy with handsewn anastomosis for ulcerative colitis

Emoto S, Hata K, Nozawa H, Kawai K, Tanaka T, Nishikawa T, Shuno Y, Sasaki K, Kaneko M, Murono K, Iida Y, Ishii H, Yokoyama Y, Anzai H, Sonoda H, Ishihara S

Background/Aims: Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis and handsewn anastomosis for ulcerative colitis requires pulling down of the ileal pouch into the pelvis, which can be technically challenging. We...
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A huge intraductal papillary neoplasm of the bile duct treated by right trisectionectomy after right portal vein embolization

Aliyev V, Yasuchika , Hammad A, Tajima T, Fukumitsu , Hata K, Okajima H, Uemoto S

Intraductal papillary neoplasm of the bile duct (IPNB) is a rare variant of bile duct tumors characterized by papillary growth within the bile duct lumen and recognized precursor of invasive...
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Antibody production after SARS-CoV2 vaccination and COVID-19 incidence in liver transplant recipients

Masano Y, Ito T, Aoki H, Hirata M, Okumura S, Anazawa T, Nagai K, Hata K, Hatano E

Background: Organ transplant recipients are immunocompromised and at high risk for COVID-19. In the present study, we investigated the antibody production after SARS-CoV2 vaccination and COVID-19 incidence in liver transplant...
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Perianal and Vulvar Extramammary Paget Disease: A Report of Six Cases and Mapping Biopsy of the Anal Canal

Nagai Y, Kazama S, Yamada D, Miyagawa T, Murono K, Yasuda K, Nishikawa , Tanaka T, Kiyomatsu , Hata K, Kawai K, Masui Y, Nozawa H, Yamaguchi , Ishihara S, Kadono T, Watanabe T

Treatment of perianal and vulvar extramammary Paget disease (EMPD), rare intraepithelial malignancies, is often challenging because of its potential to spread into the anal canal. However, there is still no...
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A 4-Year Follow-up Cohort Study of the Respiratory Functions in Toner-handling Workers

Yanagi N, Kitamura H, Mizuno M, Hata K, Uchiyama T, Kuga H, Matsushita T, Kurosaki S, Uehara M, Ogami A, Higashi T

BACKGROUND: Focusing on the respiratory function for health effect indices, we conducted a cross-sectional study on workers who did and did not handle toner to compare the longitudinal changes. METHODS: Among...
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