- Vestibular Hair Cell Regeneration in Guinea Pig after Gentamicin Damage
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Jeon SJ, Chang SO, Jung JY, Choi WI, Rhee CK
- KMID: 2276358
- Korean J Otolaryngol-Head Neck Surg.
- 2005 Mar;48(3):302-309.
BACKGROUND AND OBJECTIVES: The recovery of the vestibular sensory epithelia of guinea pigs after gentamicin (GM) induced hair cell injury was assessed both quantitatively and qualitatively with a functional study... -
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- Development of Multichannel Vestibular Prosthesis for Treatment of Bilateral Vestibular Deficiency
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Ahn JH
- KMID: 1426533
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2013 Jan;56(1):1-6.
- doi: 10.3342/kjorl-hns.2013.56.1.1
Bilateral loss of vestibular sensation from injuries of vestibular hair cells causes individuals suffering poor vision during head movement, postural instability, chronic disequilibrium, and cognitive distraction. A vestibular prosthesis analogous... -
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- Preventive and Therapeutic Effects of Low Level Laser Irradiation on Gentamicin-Induced Vestibulotoxicity in Rat Utricles
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Kim JB, Jung JY, Ahn JC, Rhee CK, Oh YH
- KMID: 1978423
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Jan;52(1):19-28.
- doi: 10.3342/kjorl-hns.2009.52.1.19
BACKGROUND AND OBJECTIVES: The purpose of this study was to investigate the effects of low level laser for the prevention and treatment of aminoglycoside-induced vestibular ototoxicity. MATERIALS AND METHOD: An organotypic... -
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- Alteration in Expression of p27(Kip1) in Mouse Vestibular Epithelia during Apoptosis Induced by Gentamicin
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Lee JE, Roh HK, Kim BI, Jung SS, Lee SH
- KMID: 2276244
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Oct;47(10):968-972.
BACKGROUND AND OBJECTIVES: p27(Kip1), a novel cyclin-dependent kinase inhibitor, plays a crucial role in regulation of cell proliferation during development of inner ear. In addition, p27(Kip1) is known to regulate... -
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- Isolation of Voltage Dependent Calcium Current in Chick Inner Hair Cell
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Lee SH, Shin MC, Ahn TH, Kim KY, Kim K, Min HJ, Park CW
- KMID: 2277079
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Aug;52(8):655-659.
- doi: 10.3342/kjorl-hns.2009.52.8.655
BACKGROUND AND OBJECTIVES: Voltage dependent calcium channel (VDCC) mediates calcium ion influx and controls neurotransmitter release in excitable cells. Hair cells in vertebrates cochlea are known to express L-type VDCC.... -
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- A Promotive Effect of Low Level Laser on Hair Cell Viability in Postnatal Organotypic Culture of Rat Utricles
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Chung YW, Ahn JC, Lim ES, Kim YS, Lee MY, Jung JY, Rhee CK
- KMID: 1603823
- J Korean Bal Soc.
- 2006 Jun;5(1):29-34.
BACKGROUND AND OBJECTIVES: To culture and maintain mammalian hair cells is still a big challenge. In this study, long-term organotypic culture of rat utricular maculae was established to study vestibular... -
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- Changes in Vestibular Nerve Activity Following Acute Hypotension in Rats
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Park BR, Kim MS, Yee GH, Moon MJ, Kim JH, Jin YZ, Kim YS
- KMID: 2285278
- Korean J Physiol Pharmacol.
- 2003 Apr;7(2):85-90.
The basic mechanism for the excitation of the peripheral vestibular receptors following acute hypotension induced by sodium nitroprusside (SNP) or hemorrhage was investigated in anesthetized rats. Electrical activity of the... -
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- A Promotive Effect of Low-Level Laser on Hair Cell Regeneration Following Gentamicin Induced Ototoxicity in Postnatal Organotypic Culture of Rat Utricles
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Chung YW, Ahn JC, Lim ES, Kim YS, Lee SH, Lee MY, Rhee CK
- KMID: 2074639
- Korean J Otolaryngol-Head Neck Surg.
- 2007 Jan;50(1):25-30.
BACKGROUND AND OBJECTIVES: In normal postnatal mammalian inner ear sensory epithelium, regeneration of hair cells is a very rare event, but there is hair cell regeneration with partial restoration of... -
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- Role of peripheral vestibular receptors in the control of blood pressure following hypotension
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Jin GS, Li XL, Jin YZ, Kim MS, Park BR
- KMID: 2414260
- Korean J Physiol Pharmacol.
- 2018 Jul;22(4):363-368.
- doi: 10.4196/kjpp.2018.22.4.363
Hypotension is one of the potential causes of dizziness. In this review, we summarize the studies published in recent years about the electrophysiological and pharmacological mechanisms of hypotension-induced dizziness and... -
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- Minocycline Protects Vestibular Hair Cells from Neomycin-Induced Ototoxicity by Inhibiting Reactive Oxygen Species Production and Caspase-3 Activity
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Kim YS, Ahn JC, Baek IY, Rhee CK, Jung JY
- KMID: 1593092
- Korean J Otolaryngol-Head Neck Surg.
- 2006 Dec;49(12):1159-1164.
BACKGROUND AND OBJECTIVES: Aminoglycosides, a commonly used antibiotic agent, destroys the sensory hair cells in the cochlear and vestibular system leading to irreversible hearing loss and balance problem. Minocycline, a... -
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- Antioxidant and Anti-Apoptotic Effect of Melatonin on the Vestibular Hair Cells of Rat Utricles
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Kim JB, Jung JY, Ahn JC, Rhee CK, Hwang HJ
- KMID: 1466553
- Clin Exp Otorhinolaryngol.
- 2009 Mar;2(1):6-12.
- doi: 10.3342/ceo.2009.2.1.6
OBJECTIVES: Aminoglycosides are commonly used antibiotic agents, and they are known to generate free oxygen radicals within the inner ear and to cause vestibulo-cochlear toxicity and permanent damage to the... -
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- Expression of Caveolin-1 in the Differentiated Vestibular Cell Line (UB/UE-1) after Gentamicin Toxicity
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Cho BH, Kim KS, Kim MW, Kim MS, Park BR
- KMID: 2328955
- J Korean Bal Soc.
- 2005 Dec;4(2):243-249.
BACKGROUND AND OBJECTIVES: The caveolin is known as a mediator of cell death or survival of injured cell and inhibitor of various signaling pathways. We examined expression of caveolin-1 involved... -
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- The Protective Effect of Epigallocatechin-3-Gallate Against Gentamicin Vestibular Ototoxicity in Type I Vestibular Hair Cell of Guinea Pig
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Choi YH, Lee SS, Moon SJ, Ahn BH, Kim NG, Jeong HS, Park JS, Cho HH, Cho YB
- KMID: 1978142
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Apr;57(4):226-232.
- doi: 10.3342/kjorl-hns.2014.57.4.226
BACKGROUND AND OBJECTIVES: Gentamicin (GM) is well known for its vestibulotoxicity. There have been many reports about vestibulotoxicity, however, its mechanism is still unclear. So far, it is known that... -
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