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Successful Endosonography-Guided Drainage of an Intra-Abdominal Abscess in a 1-Year-Old Infant

Ito Y, Isayama H, Nakai Y, Umefune G, Sato T, Nakahara S, Suwa J, Kato K, Nakata R

  • Gut Liver.
  • 2016 May;10(3):483-485.
  • doi: 10.5009/gnl15381
Endoscopic ultrasound (EUS)-guided intervention has been established as a safe, effective and minimally invasive procedure for various diseases in adults, but there have been limited reports in pediatric patients. Herein,...
Endoscopic Intervention through Endoscopic Retrograde Cholangiopancreatography in the Management of Symptomatic Pancreas Divisum: A Long-Term Follow-Up Study

Lu Y, Xu B, Chen L, Bie LK, Gong B

  • Gut Liver.
  • 2016 May;10(3):476-482.
  • doi: 10.5009/gnl15362
BACKGROUND/AIMS: To evaluate the efficacy and safety of endoscopic retrograde cholangiopancreatography (ERCP) for the treatment of symptomatic pancreas divisum (PD) and to discuss whether ERCP procedures and outcomes in younger...
Photodynamic Therapy Plus Chemotherapy Compared with Photodynamic Therapy Alone in Hilar Nonresectable Cholangiocarcinoma

Wentrup R, Winkelmann N, Mitroshkin A, Prager M, Voderholzer W, Schachschal G, Jürgensen C, Büning C

  • Gut Liver.
  • 2016 May;10(3):470-475.
  • doi: 10.5009/gnl15175
BACKGROUND/AIMS: Standard treatments are not available for hilar nonresectable cholangiocarcinoma (NCC). It is unknown whether combination therapy of photodynamic therapy (PDT) plus systemic chemotherapy is superior to PDT alone. METHODS: We...
Association between Smoking and the Progression of Computed Tomography Findings in Chronic Pancreatitis

Lee JW, Kim HG, Lee DW, Han J, Kwon HY, Seo CJ, Oh JH, Lee JH, Jung JT, Kwon JG, Kim EY

  • Gut Liver.
  • 2016 May;10(3):464-469.
  • doi: 10.5009/gnl14289
BACKGROUND/AIMS: Smoking and alcohol intake are two well-known risk factors for chronic pancreatitis. However, there are few studies examining the association between smoking and changes in computed tomography (CT) findings...
PNPLA3 rs738409 Polymorphism Associated with Hepatic Steatosis and Advanced Fibrosis in Patients with Chronic Hepatitis C Virus: A Meta-Analysis

Fan JH, Xiang MQ, Li QL, Shi HT, Guo JJ

  • Gut Liver.
  • 2016 May;10(3):456-463.
  • doi: 10.5009/gnl15261
BACKGROUND/AIMS: The recognition of a correlation between patatin-like phospholipase domain containing-protein 3 (PNPLA3) rs738409 (C>G) and the severity of liver steatosis or fibrosis in chronic hepatitis C (CHC) has not...
Association of IL28B Genotypes and Baseline Serum Interferon-γ-Inducible-Protein-10 Levels with Treatment Response in Hepatitis C Virus Patients in China

Zhang R, Shao C, Huo N, Li M, Xu X

  • Gut Liver.
  • 2016 May;10(3):446-455.
  • doi: 10.5009/gnl15162
BACKGROUND/AIMS: Several studies have demonstrated that serum interferon-γ-inducible-protein-10 (IP-10) levels at baseline and single nucleotide polymorphisms (SNPs) near the IL28B gene were associated with viral response and treatment outcomes. Our...
Relationships between Genetic Variations of PNPLA3, TM6SF2 and Histological Features of Nonalcoholic Fatty Liver Disease in Japan

Akuta N, Kawamura Y, Arase Y, Suzuki F, Sezaki H, Hosaka T, Kobayashi , Kobayashi , Saitoh S, Suzuki Y, Ikeda K, Kumada H

  • Gut Liver.
  • 2016 May;10(3):437-445.
  • doi: 10.5009/gnl15163
BACKGROUND/AIMS: It is important to determine the noninvasive parameters of histological features in nonalcoholic fatty liver disease (NAFLD). The aim of this study was to investigate the value of genetic...
Predicting Liver-Related Events Using Transient Elastography in Chronic Hepatitis C Patients with Sustained Virological Response

Lee HW, Chon YE, Kim SU, Kim BK, Park JY, Kim DY, Ahn SH, Jung KS, Park YN, Han KH

  • Gut Liver.
  • 2016 May;10(3):429-436.
  • doi: 10.5009/gnl15021
BACKGROUND/AIMS: Few studies have investigated prognostic factors for the development of liver-related events (LREs) in patients with chronic hepatitis C (CHC) who achieve sustained virological response (SVR). METHODS: We analyzed 190...
Endoscopic and Clinical Factors Affecting the Prognosis of Colorectal Endoscopic Submucosal Dissection-Related Perforation

Kang DU, Choi Y, Lee HS, Lee HJ, Park SH, Yang DH, Yoon SM, Kim KJ, Ye BD, Myung SJ, Yang SK, Kim JH, Byeon JS

  • Gut Liver.
  • 2016 May;10(3):420-428.
  • doi: 10.5009/gnl15252
BACKGROUND/AIMS: Although colorectal endoscopic submucosal dissection (ESD)-related perforation is not uncommon, the factors affecting clinical outcomes after perforation have not been investigated. This study was designed to investigate the factors...
Long-Term Effects of Bone Marrow-Derived Mesenchymal Stem Cells in Dextran Sulfate Sodium-Induced Murine Chronic Colitis

Lee HJ, Oh SH, Jang HW, Kwon JH, Lee KJ, Kim CH, Park SJ, Hong SP, Cheon JH, Kim TI, Kim WH

  • Gut Liver.
  • 2016 May;10(3):412-419.
  • doi: 10.5009/gnl15229
BACKGROUND/AIMS: Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown beneficial effects in experimental colitis models, but the underlying mechanisms are not fully understood. We investigated the long-term effects of BM-MSCs,...
The Effect of DA-6034 on Intestinal Permeability in an Indomethacin-Induced Small Intestinal Injury Model

Kwak DS, Lee OY, Lee KN, Jun DW, Lee HL, Yoon BC, Choi HS

  • Gut Liver.
  • 2016 May;10(3):406-411.
  • doi: 10.5009/gnl15251
BACKGROUND/AIMS: DA-6034 has anti-inflammatory activities and exhibits cytoprotective effects in acute gastric injury models. However, explanations for the protective effects of DA-6034 on intestinal permeability are limited. This study sought...
Factors Associated with Anxiety and Depression in Korean Patients with Inactive Inflammatory Bowel Disease

Kim MC, Jung YS, Song YS, Lee JI, Park JH, Sohn CI, Choi KY, Park DI

  • Gut Liver.
  • 2016 May;10(3):399-405.
  • doi: 10.5009/gnl15188
BACKGROUND/AIMS: Psychological distress is highly prevalent in patients with inflammatory bowel disease (IBD). We evaluated the disease characteristics and socioeconomic factors associated with anxiety and depression in Korean patients with...
Factors Contributing to the Preference of Korean Patients with Crohn's Disease When Selecting an Anti-Tumor Necrosis Factor Agent (CHOICE Study)

Kim ES, Kim KO, Jang BI, Lee CK, Kim HJ, Lee KM, Kim YS, Eun CS, Jung SA, Yang SK, Lee J, Kim TO, Jung Y, Seo GS, Yoon SM, the IBD Study Group of the Korean Association for the Study of the Intestinal Diseases (KASID)

  • Gut Liver.
  • 2016 May;10(3):391-398.
  • doi: 10.5009/gnl15126
BACKGROUND/AIMS: Two comparable anti-tumor necrosis factor (TNF) agents with different routes of administration (intravenous [iv] infliximab [IFX] vs subcutaneous [sc] adalimumab [ADA]) are available for patients with Crohn's disease (CD)...
Tryptase and Protease-Activated Receptor 2 Expression Levels in Irritable Bowel Syndrome

Liang WJ, Zhang G, Luo HS, Liang LX, Huang D, Zhang FC

  • Gut Liver.
  • 2016 May;10(3):382-390.
  • doi: 10.5009/gnl14319
BACKGROUND/AIMS: Previous studies have revealed that mast cells (MCs) may activate the protease-activated receptors and release of neuropeptides involved in the pathogenesis of irritable bowel syndrome (IBS). The levels of...
The Performance of a Modified Glasgow Blatchford Score in Predicting Clinical Interventions in Patients with Acute Nonvariceal Upper Gastrointestinal Bleeding: A Vietnamese Prospective Multicenter Cohort Study

Quach DT, Dao NH, Dinh MC, Nguyen CH, Ho LX, Nguyen ND, Le QD, Vo CM, Le SK, Hiyama T

  • Gut Liver.
  • 2016 May;10(3):375-381.
  • doi: 10.5009/gnl15254
BACKGROUND/AIMS: To compare the performance of a modified Glasgow Blatchford score (mGBS) to the Glasgow Blatchford score (GBS) and the pre-endoscopic Rockall score (RS) in predicting clinical interventions in Vietnamese...
Astaxanthin Inhibits Proliferation of Human Gastric Cancer Cell Lines by Interrupting Cell Cycle Progression

Kim JH, Park JJ, Lee BJ, Joo MK, Chun HJ, Lee SW, Bak YT

  • Gut Liver.
  • 2016 May;10(3):369-374.
  • doi: 10.5009/gnl15208
BACKGROUND/AIMS: Astaxanthin is a carotenoid pigment that has antioxidant, antitumoral, and anti-inflammatory properties. In this in vitro study, we investigated the mechanism of anticancer effects of astaxanthin in gastric carcinoma...
The IL-1B Genetic Polymorphism Is Associated with Aspirin-Induced Peptic Ulcers in a Korean Ethnic Group

Cho JH, Choi JS, Chun SW, Lee S, Han KJ, Kim HM

  • Gut Liver.
  • 2016 May;10(3):362-368.
  • doi: 10.5009/gnl15129
BACKGROUND/AIMS: Single nucleotide polymorphisms (SNPs) are associated with aspirin-induced peptic ulcers. However, SNPs of specific genes vary among races, and data regarding SNPs in the Korean population are scarce. In...
The Effects of Helicobacter pylori Eradication Therapy for Chronic Idiopathic Thrombocytopenic Purpura

Hwang JJ, Lee DH, Yoon H, Shin CM, Park YS, Kim N

  • Gut Liver.
  • 2016 May;10(3):356-361.
  • doi: 10.5009/gnl14483
BACKGROUND/AIMS: The aim of this study was to evaluate the ability of Helicobacter pylori eradication treatment to increase platelet counts in Korean patients with chronic idiopathic thrombocytopenic purpura (ITP). METHODS: A...
Gastroprotective Effects of PMK-S005 against Ethanol-Induced Acute Gastric Damage in Rats

Choi YJ, Kim N, Lee JY, Nam RH, Seo JH, Lee S, Kim HJ, Choi YJ, Lee HS, Lee DH

  • Gut Liver.
  • 2016 May;10(3):348-355.
  • doi: 10.5009/gnl14509
BACKGROUND/AIMS: This study aimed to examine the gastroprotective effects of PMK-S005, which is a synthetic S-allyl-L-cysteine (SAC; a sulfur-containing amino acid), against acute ethanol-induced gastric damage in rats. METHODS: Sprague-Dawley rats...
Systemic Chemotherapy in Advanced Pancreatic Cancer

Lee HS, Park SW

  • Gut Liver.
  • 2016 May;10(3):340-347.
  • doi: 10.5009/gnl15465
Pancreatic cancer remains one of the most lethal cancers. These patients often have multiple symptoms, and integrated supportive care is critical in helping them remain well for as long as...

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