- Better Failure-Free Survival and Graft-versus-Host Disease-Free/Failure Free Survival with Fludarabine-Based Conditioning in Stem Cell Transplantation for Aplastic Anemia in Children
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Im SH, Kim BR, Park SM, Yoon BA, Hwang TJ, Baek HJ, Kook H
- KMID: 2470779
- J Korean Med Sci.
- 2020 Feb;35(7):e46.
- doi: 10.3346/jkms.2020.35.e46
BACKGROUND: This study aimed to assess the outcome of stem cell transplantation (SCT), including overall survival (OS), failure-free survival (FFS) and graft-versus-host disease (GvHD)-free/failure-free survival (GFFS), and to analyze prognostic... -
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- Clinical significance of T cell receptor excision circle (TREC) quantitation after allogenic HSCT
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Mikhael NL, Elsorady M
- KMID: 2466593
- Blood Res.
- 2019 Dec;54(4):274-281.
- doi: 10.5045/br.2019.54.4.274
BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is a well-established treatment modality for a variety of diseases. Immune reconstitution is an important event that determines outcomes. The immune recovery of T... -
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- Clinical Symptoms and Signs of Dry Eye Disease after Allogeneic Hematopoietic Stem Cell Transplantation
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Beak JU, Ha MJ, Yi R, Yoo YS, Kim HS, Na KS
- KMID: 2466164
- J Korean Ophthalmol Soc.
- 2019 Dec;60(12):1148-1154.
- doi: 10.3341/jkos.2019.60.12.1148
PURPOSE: To identify the symptoms and signs of patients with dry eye disease (DED) after allogenic hematopoietic stem cell transplantation (HSCT) and analyze the correlations between these signs and symptoms. METHODS:... -
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- Mesenchymal Stem Cells from the Wharton's Jelly of the Human Umbilical Cord: Biological Properties and Therapeutic Potential
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Marino L, Castaldi M, Rosamilio , Ragni E, Vitolo R, Fulgione C, Castaldi S, Serio B, Bianco R, Guida M, Selleri C
- KMID: 2465893
- Int J Stem Cells.
- 2019 Jul;12(2):218-226.
- doi: 10.15283/ijsc18034
Wharton's jelly mesenchymal stem cells (WJ-MSCs) are a class of stem cells with high differentiative potential, an immuno-privileged status and easy access for collection, which raise no legal or ethical... -
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- Rehabilitation in Children With Sclerodermoid Chronic Graft-Versus-Host Disease: Case Series
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Jung M, Sung IY, Ko EJ
- KMID: 2453926
- Ann Rehabil Med.
- 2019 Jun;43(3):347-351.
- doi: 10.5535/arm.2019.43.3.347
Joint contracture in chronic graft-versus-host disease (cGVHD) is refractory to treatment, and tends to deteriorate gradually over time. There is scant clinical research focusing on timing and intensity of rehabilitation... -
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- Characterization of Plasmodium berghei Homologues of T-cell Immunomodulatory Protein as a New Potential Candidate for Protecting against Experimental Cerebral Malaria
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Cui A, Li Y, Zhou X, Wang L, Luo E
- KMID: 2448141
- Korean J Parasitol.
- 2019 Apr;57(2):101-115.
- doi: 10.3347/kjp.2019.57.2.101
The pathogenesis of cerebral malaria is biologically complex and involves multi-factorial mechanisms such as microvascular congestion, immunopathology by the pro-inflammatory cytokine and endothelial dysfunction. Recent data have suggested that a... -
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- Predictive Role of Circulating Immune Cell Subtypes Early after Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Acute Leukemia
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Kim TW, Park SS, Lim JY, Min GJ, Park S, Jeon YW, Yahng SA, Shin SH, Lee SE, Yoon JH, Cho BS, Eom KS, Lee S, Kim HJ, Min CK
- KMID: 2447226
- Int J Stem Cells.
- 2019 Mar;12(1):73-83.
- doi: 10.15283/ijsc18094
BACKGROUND AND OBJECTIVES: Cells of innate immunity normally recover in the first weeks to months after allogenenic hematopoietic stem cell transplantation (allo-HSCT). Their relevance in terms of graft-versus-host disease (GVHD)... -
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- Late Complications of Allogenic Stem Cells Transplantation in Leukaemia
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Kanagasundram S, Amini F
- KMID: 2441250
- Tissue Eng Regen Med.
- 2019 Feb;16(1):1-9.
- doi: 10.1007/s13770-018-0157-3
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) can cure leukaemia. However, long term complications of post transplantation interfere with the patients’ full recovery. The objective of this review was to... -
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- Skewed Dendritic Cell Differentiation of MyD88-Deficient Donor Bone Marrow Cells, Instead of Massive Expansion as Myeloid-Derived Suppressor Cells, Aggravates GVHD
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Lee YK, Ju JM, Shon WJ, Oh S, Min CK, Kang MS, Shin DM, Choi EY
- KMID: 2429836
- Immune Netw.
- 2018 Dec;18(6):e44.
- doi: 10.4110/in.2018.18.e44
Graft-versus-host disease (GVHD), a life-threatening complication after bone marrow transplantation (BMT), is induced by activation of alloreactive donor T cells. Our previous study demonstrated that transplantation of myeloid differentiation factor... -
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- Scabies mimicking graft versus host disease in a hematopoietic cell transplant recipient
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Kim D, Choi SH, Lee DY, Kim J, Cho E, Yoo KH, Koo HH, Kim YJ
- KMID: 2433706
- Korean J Pediatr.
- 2018 Nov;61(11):371-373.
- doi: 10.3345/kjp.2018.07199
Scabies is a highly contagious skin infestation caused by the mite, Sarcoptes scabiei var. hominis. Complex responses to scabies mites in the innate, humoral, and cellular immune systems can cause... -
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- Association of FOXP3 Single Nucleotide Polymorphisms With Clinical Outcomes After Allogenic Hematopoietic Stem Cell Transplantation
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Nam M, Shin S, Park KU, Kim I, Yoon SS, Kwon TK, Song EY
- KMID: 2429126
- Ann Lab Med.
- 2018 Nov;38(6):591-598.
- doi: 10.3343/alm.2018.38.6.591
BACKGROUND: Forkhead box P3 (FOXP3) is an important marker of regulatory T cells. FOXP3 polymorphisms are associated with autoimmune diseases, cancers, and allograft outcomes. We examined whether single nucleotide polymorphisms... -
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- Outcome of Hematopoietic Stem Cell Transplantation in Wiskott-Aldrich Syndrome
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Kim BK, Hong KT, Kang HJ, Choi JY, An HY, Shin HY
- KMID: 2435407
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):149-153.
- doi: 10.15264/cpho.2018.25.2.149
BACKGROUND: Wiskott-Aldrich syndrome (WAS) is a very rare disease and patients who do not receive timely treatment suffer from bleeding, infection, and malignancy. Hematopoietic stem cell transplantation (HSCT) has been... -
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- Transfusion practice in neonates
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Kim DH
- KMID: 2422364
- Korean J Pediatr.
- 2018 Sep;61(9):265-270.
- doi: 10.3345/kjp.2018.06849
Neonates, especially extremely low birth weight infants, are among the groups of patients undergoing transfusion frequently. Since they are exposed to higher specific transfusion risks compared to the patients of... -
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- Third-party regulatory T cells prevent murine acute graft-versus-host disease
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Lim JY, Im KI, Song Y, Kim N, Nam YS, Jeon YW, Cho SG
- KMID: 2420010
- Korean J Intern Med.
- 2018 Sep;33(5):980-989.
- doi: 10.3904/kjim.2016.319
BACKGROUND/AIMS: Adoptive therapy with regulatory T (Treg) cells to prevent graft-versus-host disease (GVHD) would benefit from a strategy to improve homing to the sites of inflammation following hematopoietic stem cell... -
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- Allogeneic hematopoietic stem cell transplantation in congenital hemoglobinopathies with myeloablative conditioning and rabbit anti-thymocyte globulin
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Park BK, Kim HS, Kim S, Lee JW, Park YS, Jang PS, Chung NG, Jeong DC, Cho B
- KMID: 2451033
- Blood Res.
- 2018 Jun;53(2):145-151.
- doi: 10.5045/br.2018.53.2.145
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapy for β-thalassemia major (TM) and sickle cell disease (SCD) in children. Graft-versus-host disease (GVHD) and treatment-related mortality (TRM) remain... -
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- Effects of Parenteral Nutrition in Pediatric Patients with Hematopoietic Stem Cell Transplantation
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Lim SY, Jung MJ, Park JE, Kim JS, Kim SH, Lyu CJ, Son ES
- KMID: 2437436
- J Clin Nutr.
- 2018 Jun;10(1):9-19.
- doi: 10.15747/jcn.2018.10.1.9
PURPOSE: This study examined the effects of parenteral nutrition (PN) on the nutritional status, clinical improvement, and PN-related complications in pediatric patients who had undergone hematopoietic stem cell transplantation (HSCT). METHODS:... -
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- The Detailed Kinetics of Cytomegalovirus-specific T cell Responses after Hematopoietic Stem Cell Transplantation: 1 Year Follow-up Data
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Bae S, Jung J, Kim SM, Kang YA, Lee YS, Chong YP, Sung H, Lee SO, Choi SH, Kim YS, Woo JH, Lee JH, Lee JH, Lee KH, Kim SH
- KMID: 2410155
- Immune Netw.
- 2018 Apr;18(2):e2.
- doi: 10.4110/in.2018.18.e2
The detailed kinetics of the cytomegalovirus (CMV)-specific T cell response in hematopoietic stem cell transplant (HCT) recipients have not yet been fully assessed. We evaluated these kinetics of CMV-specific T... -
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- Current Perspectives on Emerging CAR-Treg Cell Therapy: Based on Treg Cell Therapy in Clinical Trials and the Recent Approval of CAR-T Cell Therapy
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Kang K, Chung J, Yang J, Kim H
- KMID: 2401566
- J Korean Soc Transplant.
- 2017 Dec;31(4):157-169.
- doi: 10.4285/jkstn.2017.31.4.157
Regulatory T cells (Treg) naturally rein in immune attacks, and they can inhibit rejection of transplanted organs and even reverse the progression of autoimmune diseases in mice. The initial safety... -
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- Allogenic Peripheral Blood Stem Cell Transplant-Induced Membranous Glomerulonephropathy as Chronic Graft-Versus-Host Disease
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Kim JE, Yoo EJ, Kim AR, Park JE, Shin GT, Kim H, Park I
- KMID: 2400920
- Korean J Med.
- 2017 Dec;92(6):541-545.
- doi: 10.3904/kjm.2017.92.6.541
Heavy proteinuria in the nephrotic range is an uncommon, often unrecognized manifestation of graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation. A few isolated case reports have been published in... -
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- Perioperative red blood cell transfusion in orofacial surgery
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Park SY, Seo KS, Karm MH
- KMID: 2390801
- J Dent Anesth Pain Med.
- 2017 Sep;17(3):163-181.
- doi: 10.17245/jdapm.2017.17.3.163
In the field of orofacial surgery, a red blood cell transfusion (RBCT) is occasionally required during double jaw and oral cancer surgery. However, the question remains whether the effect of... -
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