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Effect of Family History of Diabetes on Hemoglobin A1c Levels among Individuals with and without Diabetes: The Dong-gu Study

Lee YH, Shin MH, Nam HS, Park KS, Choi SW, Ryu SY, Kweon SS

PURPOSE: We investigated associations between family history of diabetes (FHD) and hemoglobin A1c (HbA1c) level, among people with and without diabetes. MATERIALS AND METHODS: In total, 7031 people without diabetes and...
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Rac-mediated actin remodeling and myosin II are involved in KATP channel trafficking in pancreatic beta-cells

Han YE, Lim A, Park SH, Chang S, Lee SH, Ho WK

AMP-activated protein kinase (AMPK) is a metabolic sensor activated during metabolic stress and it regulates various enzymes and cellular processes to maintain metabolic homeostasis. We previously reported that activation of...
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An insulinoma with an aberrant feeder from the splenic artery detected by super-selective arterial calcium stimulation with venous sampling

Moon JH, Kim EK, Khang AR, Kim HC, Jang JY, Cho YM

No abstract available.
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A Rat Model of Striatonigral Degeneration Generated by Simultaneous Injection of 6-Hydroxydopamine into the Medial Forebrain Bundle and Quinolinic Acid into the Striatum

Yoon HH, Kim YH, Shin ES, Jeon SR

A double toxin-double lesion strategy is well-known to generate a rat model of striatonigral degeneration (SND) such as multiple system atrophy-parkinsonian type. However, with this model it is difficult to...
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Diabetic Retinopathy Risk Factors: Plasma Erythropoietin as a Risk Factor for Proliferative Diabetic Retinopathy

Gholamhossein Y, Behrouz H, Asghar Z

PURPOSE: The purpose of this study was to evaluate whether any stage of diabetic retinopathy (DR) is associated with levels of plasma erythropoietin and other plasma parameters. METHODS: It was examined...
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Factors predictive of the failure of medical treatment in patients with pleural infection

Kim SK, Kang CU, Song SH, Cho DG, Cho KD, Kim CH

BACKGROUND/AIMS: The clinical outcomes of some patients with pleural infection may be favorable with medical treatment alone, but in others, the disease progresses and requires additional surgical treatment. However, little...
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A Web-based Health Promotion Program for Patients with Metabolic Syndrome

Kang JS, Kang HS, Jeong Y

  • KMID: 2069899
  • Asian Nurs Res.
  • 2014 Mar;8(1):82-89.
PURPOSE: The population of metabolic syndrome is increasing in Korea. The prevalence is related to lifestyle, such as lack of physical activity and irregular diet. Most patients with metabolic syndrome...
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Simulation of Oral Glucose Tolerance Tests and the Corresponding Isoglycemic Intravenous Glucose Infusion Studies for Calculation of the Incretin Effect

Kim M, Oh TJ, Lee JC, Choi K, Kim MY, Kim HC, Cho YM, Kim S

The incretin effect, which is a unique stimulus of insulin secretion in response to oral ingestion of nutrients, is calculated by the difference in insulin secretory responses from an oral...
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Association between CDH13 Variants and Cardiometabolic and Vascular Phenotypes in a Korean Population

Lee JH, Shin DJ, Park S, Kang SM, Jang Y, Lee SH

PURPOSE: Although some CDH13 single nucleotide polymorphisms (SNPs) have been shown to be determinants of blood adiponectin levels, the clinical implications of CDH13 variants are not yet completely understood. The...
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Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats

Oh TJ, Shin JY, Kang GH, Park KS, Cho YM

  • KMID: 2154249
  • Exp Mol Med.
  • 2013 Jul;45(7):e30.
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-alpha-dependent manner. We investigated whether a PPARalpha...
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Effects of D-002, a mixture of high molecular weight beeswax alcohols, on patients with nonalcoholic fatty liver disease

Illnait J, Rodriguez , Mendoza S, Fernandez , Mas R, Miranda M, Pinera J, Fernandez , Mesa M, Fernandez , Carbajal D, Gamez R

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is intimately related to insulin resistance and ranges from a benign course to liver fibrosis and cirrhosis. NAFLD management mainly involves dietary modification and...
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Relations between Long-term Glycemic Control and Postoperative Wound and Infectious Complications after Total Knee Arthroplasty in Type 2 Diabetics

Han HS, Kang SB

BACKGROUND: The authors examined whether poor preoperative glucose control, as indicated by the hemoglobin A1c (HbA1c) level of more than 8%, is associated with postoperative wound and infectious complications in...
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Is Insulin Resistance an Intrinsic Defect in Asian Polycystic Ovary Syndrome?

Lee H, Oh JY, Sung YA, Chung H

PURPOSE: Approximately 50% to 70% of women with polycystic ovary syndrome (PCOS) have some degree of insulin resistance, and obesity is known to worsen insulin resistance. Many metabolic consequences of...
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Type B insulin-resistance syndrome presenting as autoimmune hypoglycemia, associated with systemic lupus erythematosus and interstitial lung disease

Kang SM, Jin HY, Lee KA, Park JH, Baek HS, Park TS

We describe an unusual case of systemic lupus erythematosus with pulmonary manifestations presenting as hypoglycemia due to anti-insulin receptor antibodies. A 38-year-old female suffered an episode of unconsciousness and was...
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Associations between Hemoglobin Concentrations and the Clinical Characteristics of Patients with Type 2 Diabetes

Chung JO, Cho DH, Chung DJ, Chung MY

BACKGROUND/AIMS: Many studies have demonstrated an association between hemoglobin levels and cardiovascular disease in diabetic patients. The aim of this study was to determine whether there is an association between...
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Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney

Sun HK, Lee YM, Han KH, Kim HS, Ahn SH, Han SY

BACKGROUND/AIMS: Renal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve...
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Associations among Body Mass Index, Insulin Resistance, and Pancreatic beta-Cell Function in Korean Patients with New-Onset Type 2 Diabetes

Chung JO, Cho DH, Chung DJ, Chung MY

BACKGROUND/AIMS: We investigated the associations among body mass index (BMI), insulin resistance, and beta-cell function in Korean patients newly presenting with type 2 diabetes. METHODS: In total, 132 patients with new-onset...
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Differentiation of human labia minora dermis-derived fibroblasts into insulin-producing cells

Kim B, Yoon BS, Moon JH, Kim J, Jun EK, Lee JH, Kim JS, Baik CS, Kim A, Whang KY, You S

Recent evidence has suggested that human skin fibroblasts may represent a novel source of therapeutic stem cells. In this study, we report a 3-stage method to induce the differentiation of...
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Incidence and Risk Factors of Steroid-induced Diabetes in Patients with Respiratory Disease

Kim SY, Yoo CG, Lee CT, Chung HS, Kim YW, Han SK, Shim YS, Yim JJ

Glucocorticoids are effective for treating several respiratory diseases. However, they can cause hyperglycemia. This study determined the incidence and risk factors of steroidinduced diabetes mellitus (S-DM) in patients treated with...
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Relation between Obesity and Bone Mineral Density and Vertebral Fractures in Korean Postmenopausal Women

Kim KC, Shin DH, Lee SY, Im JA, Lee DC

PURPOSE: The traditional belief that obesity is protective against osteoporosis has been questioned. Recent epidemiologic studies show that body fat itself may be a risk factor for osteoporosis and bone...
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