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Effects of mutation of hepatitis B virus poly(A) signal "TATAAA" to "AATAAA" on expression of hepatitis B viral genes

Kim SH, Kim SK, Kwon YT, Rho HM

  • KMID: 1688538
  • J Korean Soc Virol.
  • 1992 Mar;22(1):37-44.
No abstract available.
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Epstein-Barr virus latent genes

Kang MS, Kieff E

Latent Epstein-Barr virus (EBV) infection has a substantial role in causing many human disorders. The persistence of these viral genomes in all malignant cells, yet with the expression of limited...
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Herpes Viral Gene Therapy for the Treatment of Head and Neck Squamous Cell Carcinoma

Kim SH

  • KMID: 2276636
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 May;49(5):474-481.
No Abstract available.
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Current Trends in Viral Gene Therapy for Human Orthopaedic Regenerative Medicine

Venkatesan JK, Rey-Rico A, Cucchiarini M

BACKGROUND: Viral vector-based therapeutic gene therapy is a potent strategy to enhance the intrinsic reparative abilities of human orthopaedic tissues. However, clinical application of viral gene transfer remains hindered by...
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Isolation and genetic characterization of Japanese encephalitis virus from equines in India

Gulati BR, Singha H, Singh BK, Virmani N, Kumar S, Singh RK

Japanese encephalitis (JE) is an important vector-borne viral disease of humans and horses in Asia. JE outbreaks occur regularly amongst humans in certain parts of India and sporadic cases occur...
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Genome-Based Virus Taxonomy with the ICTV Database Extension

Kang S, Kim YC

In 1966, the International Classification of Viruses (ICNV) was established to standardize the naming of viruses. In 1975, the organization was renamed “International Committee on Taxonomy of Viruses (ICTV),” by...
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Pandemic Threat Posed by Avian Influenza A Viruses

Lee WK

  • KMID: 1892722
  • Korean J Clin Microbiol.
  • 2004 Sep;7(2):95-104.
Phylogenetic studies of influenza A viruses have revealed species-specific lineages of viral genes, and that aquatic birds are the source of all influenza viruses in other animal species including humans,...
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Evaluation of Vascular Smooth Muscle Cell Lineages Derived from the Transgenic Mice Expressing Temperature-Sensitive Simian Virus 40 T Antigen Targeted to Smooth Muscle

Huh NE

BACKGROUND AND OBJECTIVES: As a part of efforts to evaluate effectiveness of aorta cell lineages derived from the transgenic mice in which expression of the temperature-sensitive SV40 large T antigen...
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Differential Regulation of NF-kappaB Signaling during Human Cytomegalovirus Infection

Kwon KM, Ahn JH

NF-kappaB transcription factors are key regulators of immune and stress responses, apoptosis, and differentiation. Human cytomegalovirus (HCMV) activates or represses NF-kappaB signaling at different times during infection. An initial increase...
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Effective Antitumor Activity of a Recombinant Vaccinia Virus Expressing Murine Interleukin 4

Yoon K, Kim S, Jin NY

  • KMID: 1940947
  • J Korean Soc Virol.
  • 1998 Mar;28(1):71-78.
Vaccinia virus is the prototype orthopoxvirus that has been used as a vaccine strain for small pox. This virus has been used to express a variety of cellular and viral...
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Therapeutic Angiogenesis: The Pros and Cons and the Future

Ryu JK

Despite the improvements in medical, surgical and endovascular therapies, vascular disease is still a significant, critical clinical problem. The advances in understanding the mechanisms of neovascularization and the accumulated experiences...
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Optimized clade 2.3.2.1c H5N1 recombinant-vaccine strains against highly pathogenic avian influenza

Jang JW, Lee CY, Kim IH, Choi JG, Lee YJ, Yuk SS, Lee JH, Song CS, Kim JH, Kwon HJ

A/Puerto Rico/8/34 (PR8)-derived recombinant viruses have been used for seasonal flu vaccines; however, they are insufficient for vaccines against some human-fatal H5N1 highly pathogenic avian influenza (HPAI) viruses (HPAIV) due...
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Development of Trans Attack Anticancer Gene Vaccine Interact in HPV Oncoprotein Expression Inhibition

Lee HJ, Lee SH, Kim HJ, Kim JH, Lew YO, Lee JO, Kim YW, Ahn WS, Kim CK, Lee JM, Kim DH, Namkoong S, Kang KD

  • KMID: 2272267
  • Korean J Obstet Gynecol.
  • 2004 Feb;47(2):258-263.
OBJECTIVE: Adeno-associated virus Rep 78 protein is known to inhibit the promoter site of several onco-genes and viral gene, including the human papillomavirus type 16 E6 transforming genes. In this...
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MicroRNAs in Human Diseases: From Lung, Liver and Kidney Diseases to Infectious Disease, Sickle Cell Disease and Endometrium Disease

Ha TY

MicroRNAs (miRNAs) are a class of naturally occurring small non-coding RNAs of about 22 nucleotides that have recently emerged as important regulators of gene expression at the posttranscriptional level. Recent...
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Expression of Open Reading Frame 5 Protein of Porcine Reproductive and Respiratory Syndrome Virus Using Semliki Forest Virus Expression System

Jung HS, Hwang IW, Kim SM, Kim CJ, Shin KS, Kim HS

  • KMID: 1101569
  • J Vet Sci.
  • 2002 Mar;3(1):13-18.
The ORF5 gene encodes a major envelope glycoprotein (GP5), which is one of the three major proteins of porcine reproductive and respiratory syndrome virus (PRRSV). The GP5 protein has been...
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Growth Inhibition of Cervical Cancer Cell by Lipofectin with Adeno Associated Viral Plasmid [pAAVCMVp53/lipofectin]

Seo SY, Lee JY, An WS, Jo GN, Han YJ, Lee JM, Namkoong S, Lee HY, Kim SJ, Kim SP, Kim DJ, Park YS, Kim JK, Yang JM, Park SH

  • KMID: 2269620
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):1108-1116.
PURPOSE: Cervical cancer is strongly associated with human papilloma virus [HPV] and the transforming viral genes E6 and E7 are steadily expressed by the tumor cells. To evaluate the...
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Immunogenicity of recombinant Lactobacillus plantarum NC8 expressing goose parvovirus VP2 gene in BALB/c mice

Liu YY, Yang WT, Shi SH, Li YJ, Zhao L, Shi CW, Zhou FY, Jiang YL, Hu JT, Gu W, Yang GL, Wang CF

Goose parvovirus (GPV) continues to be a threat to goose farms and has significant economic effects on the production of geese. Current commercially available vaccines only rarely prevent GPV infection....
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Combination of Mutated Herpes Simplex Virus (G207) with Radiation for the Treatment of Squamous Cell Carcinoma of the Head and Neck

Kim SH, Choi EC, Han DH, Han SJ, Kim JH, Nam JI, Kim KM

  • KMID: 2276000
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Feb;46(2):139-146.
BACKGROUND AND OBJECTIVES: G207 virus is an ideal candidate of oncolytic viral therapy. It is a multi-gene mutant of HSV-1 with a deletion at the gamma34.5 loci and a LacZ...
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Molecular characterization of duck enteritis virus CHv strain UL49.5 protein and its colocalization with glycoprotein M

Lin M, Jia R, Wang M, Gao X, Zhu D, Chen S, Liu M, Yin Z, Wang Y, Chen X, Cheng A

The UL49.5 gene of most herpesviruses is conserved and encodes glycoprotein N. However, the UL49.5 protein of duck enteritis virus (DEV) (pUL49.5) has not been reported. In the current study,...
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Improved expression by cytomegalovirus promoter/enhancer and behavior of vascular endothelial growth factor gene after myocardial injection of naked DNA

Jeong JO, Byun JH, Jeon ES, Gwon HC, Lim YS, Park JW, Yeo SJ, Lee YJ, Kim SY, Kim DK

  • KMID: 931878
  • Exp Mol Med.
  • 2002 Sep;34(4):278-284.
Direct injection of the vascular endothelial growth factor (VEGF) gene plasmid DNA into the myocardium was shown to induce development of new blood vessels to increase the circulation in...
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