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The effects of angiotensin II and thrombin on the secretion of PDGF endothelin, and PGI2 in cultured umbilical vein endothelial cells

Choo KY, Lee TS, Park HC, Oh SM, Park JK

  • KMID: 1939677
  • J Korean Vasc Surg Soc.
  • 1993 Dec;9(1):25-41.
No abstract available.
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Diagnosis and treatment of idiopathic pulmonary arterial hypertension

Kim H

  • KMID: 2256645
  • Korean J Med.
  • 2006 Jul;71(1):4-9.
Idiopathic pulmonary arterial hypertension (previous primary pulmonary hypertension) was a progressive disease with high mortality. Many patients with idiopathic pulmonary arterial hypertension did not show vasoreactivity, rapidly resulted in marked...
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Successful Conversion Arterial Switch Operation after Palliative Senning Operation

Kim JB, Park JJ, Chung SH, Park IS, Seo DM

  • KMID: 1921545
  • Korean J Thorac Cardiovasc Surg.
  • 2006 Feb;39(2):140-144.
Six year-old female having TGA, VSD with severe PHT which was considered inoperable for anatomical correction, received palliative Senning procedure. During follow-up, she was given prostacyclin and at the age...
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The Therapeutic Effect of Inhaled Iloprost in Newborn Infants with Severe Persistent Pulmonary Hypertension Refractory to Inhaled Nitric Oxide

Han YK, Lee SM, Eun HS, Kim JE, Namgung R, Park MS, Park KI, Lee C

  • KMID: 1446999
  • Korean J Perinatol.
  • 2011 Mar;22(1):57-63.
Inhaled iloprost, a stable carbacyline derivative of prostacyclin, has been used recently for the treatment of adults with pulmonary hypertension but only few reports are available about its use in...
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Effect of Prostacyclin on Pulmonary Ischemia-reperfusion Injury according to the State of Lung Inflation

Kim KM, Oh YS

BACKGROUND: Prostacyclin (PGI2) is a commonly used protective agent against pulmonary ischemia-reperfusion injury. In this study, it was postulated that the protective effect of PGI2 on pulmonary ischemia-reperfusion injury would...
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Pharmacotherapy for pulmonary arterial hypertension

Kim C, Park YB

Although pulmonary arterial hypertension (PAH) is an orphan disease with high mortality and for which there is no cure, current treatment have led to considerable gains in the outcomes of...
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Inhaled iloprost for the treatment of patient with Fontan circulation

Kim YH, Chae MH, Choi DY

Decreased exercise capacity after Fontan surgery is relatively common and the failure of the Fontan state gradually increases with age. However, there is no further treatment for patients with Fontan...
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The Effect of VEGF (Vascular endothelial growth factor) on Endothelial Cells in Pathogenesis of Preeclampsia

Cho YK, Lee HK

  • KMID: 1925520
  • Korean J Obstet Gynecol.
  • 2002 Aug;45(8):1354-1359.
OBJECTIVE: Preeclampsia is primarily a disorder of the maternal endothelium. The objective of this study was to assess the effect of VEGF on human umbilical vein endothelial cells (HUVEC) in...
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Effect of Various Irrigation Fluids of Arterial and Venous Endothelium after Ischemia

Yoon CH, Kim HJ

This study examines the extent of endothelial damage following a period of irrigation with various crystalloid irrigation fluds. Both arteries and veins were evaluated after irrigation with normal saline, lactated...
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A case of prostacyclin responsive pulmonary hypertension complicated in a patient with systemic lupus erythematosus

Kim HS, Ryu YJ, Lee JS, Shin GJ, Sung SH, Chung IM

  • KMID: 1985135
  • Korean J Med.
  • 2002 Nov;63(5):581-586.
A 36-year-old woman was admitted due to dyspnea and generalized edema, and was diagnosed as systemic lupus erythematosus and right ventricular heart failure due to accompanied pulmonary hypertension. The patient...
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Pulmonary hypertension in infants with bronchopulmonary dysplasia

Kim GB

An increase in the number of preterm infants and a decrease in the gestational age at birth have resulted in an increase in the number of patients with significant bronchopulmonary...
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Moderate and Deep Hypothermia Produces Hyporesposiveness to Phenylephrine in Isolated Rat Aorta

Cho JW, Lee CH, Jang JS, Kwon OC, Roh WS, Kim JE

  • KMID: 1987359
  • Korean J Thorac Cardiovasc Surg.
  • 2013 Dec;46(6):402-412.
BACKGROUND: Moderate and severe hypothermia with cardiopulmonary bypass during aortic surgery can cause some complications such as endothelial cell dysfunction or coagulation disorders. This study found out the difference of...
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Prostacyclin synthase C1117A polymorphism is not associated with variant angina

Seong IW, Lim DS, Kim JH, Lee JH, Choi SW, Jeong JO

  • KMID: 1652684
  • Korean J Med.
  • 2004 Apr;66(4):383-388.
BACKGROUND: Coronary artery spasm plays an important role in the pathogenesis of variant angina (VA). Prostacyclin is one of the endothelium derived relaxing factors. The association between the novel single...
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Studies on Experimental Vasospasm: Effect of Calcium Antagonist and Prostacyclin on Serotonin Induced Contraction of Carotid Artery in the Cat

Lee KC

  • KMID: 2068280
  • J Korean Neurosurg Soc.
  • 1986 Sep;15(3):461-472.
One of the most severe complication of the rupture of aneurysms is the resultant spasm of cerebral arteries leading to ischemia, edema, and infarction of large area of the brain....
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Efficacy of Oral Prostaglandin I2 in Patients with Chronic Nonspecific Vertigo

Kim JW, Lim HW, An YS, Choi SH, Park HJ, Chung JW

  • KMID: 2316791
  • Res Vestib Sci.
  • 2011 Dec;10(4):115-120.
BACKGROUND AND OBJECTIVES: The aim of this study is to evaluate the efficacy of prostaglandin I2 (PGI2) in the patients with chronic nonspecific vertigo using questionnaires of dizziness handicap inventory...
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Inhaled Iloprost as a First-Line Therapy for Persistent Pulmonary Hypertension of the Newborn

Kim SH, Lee HJ, Kim NS, Park HK

PURPOSE: Persistent pulmonary hypertension of the newborn (PPHN) is a potentially fatal disease. Inhaled iloprost, a stable analogue of prostacyclin, has recently been used as a therapeutic option. However, there...
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Effect of Calcium Antagonist(Nicardipine) on CBF, CMRO2, and CMRG in Experimental Cerebral Vasopasm

Park JY, Lee KC, Chu JW

  • KMID: 2067785
  • J Korean Neurosurg Soc.
  • 1989 May;18(5):661-670.
The author investigated the cerebral circulatory and metabolic effects of systemic and intracisternal administration of nicardipine in a canine model of chronic cerebral vasospasm. Twenty-one dogs were assigned to one...
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Effects of PGI2 on the ATP-sensitive Potassium Channel Activity in the Isolated Rat Cardiac Myocytes

Ju JM, Choi DS, Piao LH, Kim JH

  • KMID: 1613959
  • Chonnam Med J.
  • 2003 Sep;39(3):162-170.
It was examined that the effects of PGI2 on the ATP-sensitive potassium channel (KATP channel) activity in the rat myocardium using patch clamp and action potential measurement techniques. PGI2, doses...
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Retrospective Study of Clinical Features and Courses of Raynaud's Phenomenon

Yoo KE, Lee KB, Kim DI

  • KMID: 1940998
  • J Korean Soc Vasc Surg.
  • 2006 May;22(1):1-5.
PURPOSE: Raynaud's phenomenon is characterized by recurrent episodes of arterial vasospasm of the digits upon exposure to cold, and this can occur alone or in association with other underlying conditions....
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Insulin Resistance and Erectile Dysfunction

Kim SC

Insulin resistance is a hallmark of metabolic syndrome, including type 2 diabetes mellitus and obesity which are characterized by endothelial dysfunction. The endothelial dysfunction leads to erectile dysfunction (ED). Thus,...
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