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Pathophysiological Role of Endothelin-1 and Clinical Usefulness of Endothelin Antagonists

Seo B

No abstract available.
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Changes of plasma endothelin in non-insulin dependent diabetes mellitus

Woo JT, Lee HR, Kim JW, Kim YS, Kim KW, Choi YK

  • KMID: 1700003
  • J Korean Diabetes Assoc.
  • 1991 Dec;15(2):251-256.
No abstract available.
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The effects of angiotensin II and thrombin on the secretion of PDGF endothelin, and PGI2 in cultured umbilical vein endothelial cells

Choo KY, Lee TS, Park HC, Oh SM, Park JK

  • KMID: 1939677
  • J Korean Vasc Surg Soc.
  • 1993 Dec;9(1):25-41.
No abstract available.
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Moving Beyond the Endothelium is Still Challenging-Complex Interplay between Endothelin and Reactive Oxygen Species in Pulmonary Arterial Hypertension

Chung H, Sohn IS

No abstract available.
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Comparison of Endothelin Release in Bronchial Asthma, Chronic Obstructive Pulmonary Disease and Healthy Controls

Chang JH

  • KMID: 2251542
  • Korean J Med.
  • 1998 Jul;55(1):69-74.
OBJECTIVE: Both bronchial asthma and chronic obstructive pulmonary disease(COPD) are defined as disease entities causing sudden exacerbation of dyspnea; the former is a reversible airflow obstruction and the latter partially...
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The Effect of Endothelin-1 on IOP and Aqueous Outflow Facility in the Rabbit Eye

Jwa WB, Yoo KW, Rho SH

  • KMID: 2147776
  • J Korean Ophthalmol Soc.
  • 1996 Jan;37(1):129-135.
Endothelin(ET) is known as a family of potent hydrophobic, vasoactive peptide. We investigated the effect according to the concentrations of ET on intraocular pressure(IOP), aqueous outflow facility, pupillary diameter and...
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Refractory Digital Ulcers Treated by Botulinum Toxin and Endothelin Receptor-1 Antagonist in Anti-MDA5-Antibody-Positive Dermatomyositis

Min HK, Kim HR, Lee SH, Park SH, Oh J, Choi K

No abstract available.
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Pathogenesis of Cerebral Vasospasm

Moon CT

  • KMID: 2067613
  • J Korean Neurosurg Soc.
  • 1999 Aug;28(8):1208-1214.
Although cerebral vasospasm is the greatest cause of morbidity and mortality in patient who survive the ictus of subarachnoid hemorrhage(SAH), the pathogenesis of vasospasm remains unclear. However, recent advances in...
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Endothelium-dependent and Independent Responsiveness to Endothelin in Porcine Coronary Artery

Hong MK, Kim JJ, Lee CW, Park SW, Park SJ

BACKGROUND: The purpose of this study was to investigate the mechanism of endothelium-dependent and independent responses to endothelins (ETs) in porcine coronary artery. METHODS: The vascular rings of left anterior...
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Blood Pressure Regulation by Vasoactive Peptide Genes: Transgenic And Knockout Animal Models

Ahn D

  • KMID: 2134792
  • Electrolyte Blood Press.
  • 2005 Mar;3(1):14-23.
Hypertension is a polygenic and multifactorial disease and is intimately related to salt homeostasis. Four important vasoactive peptide systems participate in regulating blood pressure and salt homeostasis. Their interplay is...
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Endothelin increases intracellular free calcium in isolated rat nephron

Cha SH, Cho YJ, Lee KH, Endou H

  • KMID: 1554767
  • Korean J Physiol Pharmacol.
  • 1997 Oct;1(5):565-572.
In the freshly isolated rat nephron, the effect of endothelin-1, -2 and -3 (ET-1, -2 and -3) on cytosolic free calcium concentration ((Ca2+)i) was determined using the fluorescent indicator Fura-2/AM. (Ca2+)i increase was...
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SM709, Ingredient of Antimelanogenic Bamboo Extract, Blocks Endothelin-1-induced [Ca2+]i Increase in Human Melanocytes

Kim SH, Lee KM, Kim HS, Lee GS, Jeon BH, Kim KJ, Park JB

  • KMID: 1607515
  • Korean J Physiol Pharmacol.
  • 2003 Dec;7(6):311-316.
Endothelins secreted from keratinocytes are intrinsic mitogens and melanogens of human melanocytes in UVB-induced hyperpigmentation. To elucidate the cellular mechanism of antimelanogenic activity of bamboo extract, the effects of three...
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The Expression of eNOS and ET-1 in Corpus Cavernosum in Male Rat with Partial Bladder Outlet Obstruction

Park SH, Lee KS

  • KMID: 2048746
  • Chonnam Med J.
  • 2007 Apr;43(1):52-57.
Benign prostatic hyperplasia and erectile dysfunction are co-morbid disease in aging male. Relaxation and contraction of corpus cavernosum is an essential factor in the course of penile erection which are...
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Effects of Anethesia and Operation on Plasma Endothelin Levels

Yoon MH, Im WM, Lee HJ

  • KMID: 2275060
  • Chonnam Med J.
  • 1996 Dec;32(2):161-166.
Recently, it has been demonstrated that Endothelin (ET) and endothelin-related peptides are present in the blood and plasma ET levels are increased during or after operation. But, it is not...
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Altered Regulation of Endothelin, Atrial Natriuretic Peptide, and Nitric Oxide Systems in Angiotensin II-induced Hypertension

Bae EH, Kim CS, Choi JS, Ma SK, Lee JU, Kim SW

BACKGROUND: The present study aimed to determine the changes of endothelin (ET), nitric oxide, and atrial natriuretic peptide (ANP) systems in the kidney and aorta in angiotensin (Ang) II-induced hypertension. METHODS:...
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Beyond Vasodilator: Anti-Apoptotic Effect of Endothelin Receptor Antagonist

Chang SA

No abstract available.
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Effects of Endothelin on Potassium Currents in Primary Cultured Rat Microglia

Bae JH

  • KMID: 2298533
  • Korean J Aerosp Environ Med.
  • 2001 Mar;11(1):24-31.
BACKGROUND: Endothelin (ET), potent vasoconstricting peptide, are produced by endothelial cells after brain insults such as ischemia or infection and may play a role in the amplification or regulation of...
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Effects of Endothelin A Receptor Antagonist to Cellular Proliferation and Apoptosis in Neonatal Rat Heart

Choi BM, Yoo KH, Hong YS, Lee JW, Kim SK

  • KMID: 2335742
  • J Korean Pediatr Soc.
  • 2003 Jul;46(7):668-678.
PURPOSE: In order to investigate the role of endothelins in the cardiac development, the present study was designed to examine the effects of endothelin A receptor(ETAR) antagonist to the cellular...
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Expression of Endothelin-1 and Its Receptors in Cisplatin-Induced Acute Renal Failure in Mice

Lee S, Ahn D

Endothelin-1 (ET-1) is unequivocally elevated in the kidney with ischemic acute renal failure (ARF), whereas ET receptors (ET(A)R and ET(B)R) are variably expressed. Although renal functional and structural changes are...
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The Effects of Selective Cyclooxygenase-2 Inhibitor and Prostaglandin E2 Receptor Agonists on the Endothelin Axis of Prostate Cancer Cells

Kim TH, Kim YS, Myung SC, Lee SW, Won EH, Kim TH

PURPOSE: The enhanced expression of the cyclooxygenase-2 (COX-2), prostaglandin E2 receptor (EPs) and endothelin-1 (ET-1) axis is known to play a significant role in the development and progression of several...
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