- Potential of γ-Glutamyl Transferase as a Novel Risk Factor for Cardiovascular Disease
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Rhee SY
- KMID: 2549259
- Endocrinol Metab.
- 2023 Dec;38(6):667-668.
- doi: 10.3803/EnM.2023.602
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- 2023 Korean Endocrine Society Consensus Guidelines for the Diagnosis and Management of Primary Aldosteronism
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Ha J, Park JH, Kim KJ, Kim JH, Jung KY, Lee J, Choi JH, Lee SH, Hong N, Lim JS, Park BK, Kim JH, Jung KC, Cho J, Kim Mk, Chung CH, The Committee of Clinical Practice Guideline of Korean Endocrine Society, The Korean Adrenal Study Group of Korean Endocrine Society
- KMID: 2549255
- Endocrinol Metab.
- 2023 Dec;38(6):597-618.
- doi: 10.3803/EnM.2023.1789
Primary aldosteronism (PA) is a common, yet underdiagnosed cause of secondary hypertension. It is characterized by an overproduction of aldosterone, leading to hypertension and/or hypokalemia. Despite affecting between 5.9% and... -
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- Toward Systems-Level Metabolic Analysis in Endocrine Disorders and Cancer
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Lakhani A, Kang DH, Kang YE, Park JO
- KMID: 2549256
- Endocrinol Metab.
- 2023 Dec;38(6):619-630.
- doi: 10.3803/EnM.2023.1814
Metabolism is a dynamic network of biochemical reactions that support systemic homeostasis amidst changing nutritional, environmental, and physical activity factors. The circulatory system facilitates metabolite exchange among organs, while the... -
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- Long-Term Cumulative Exposure to High γ-Glutamyl Transferase Levels and the Risk of Cardiovascular Disease: A Nationwide Population-Based Cohort Study
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Baek HS, Kim B, Lee SH, Lim DJ, Kwon HS, Chang SA, Han K, Yun JS
- KMID: 2549270
- Endocrinol Metab.
- 2023 Dec;38(6):770-781.
- doi: 10.3803/EnM.2023.1726
Background: Elevated γ-glutamyl transferase (γ-GTP) levels are associated with metabolic syndrome. We investigated the association of cumulative exposure to high γ-GTP with the risk of cardiovascular disease (CVD) in a... -
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- Update on Current Evidence for the Diagnosis and Management of Nonfunctioning Pituitary Neuroendocrine Tumors
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Whyte E, Nezu M, Chik C, Tateno T
- KMID: 2549257
- Endocrinol Metab.
- 2023 Dec;38(6):631-654.
- doi: 10.3803/EnM.2023.1838
Pituitary neuroendocrine tumors (PitNETs) are the third most frequently diagnosed intracranial tumors, with nonfunctioning PitNETs (nfPitNETs) accounting for 30% of all pituitary tumors and representing the most common type of... -
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- Increased Risk of Hip Fracture in Patients with Acromegaly: A Nationwide Cohort Study in Korea
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Kim J, Hong N, Choi J, Moon JH, Kim EH, Lee EJ, Kim SG, Ku CR
- KMID: 2549262
- Endocrinol Metab.
- 2023 Dec;38(6):690-700.
- doi: 10.3803/EnM.2023.1782
Background: Acromegaly leads to various skeletal complications, and fragility fractures are emerging as a new concern in patients with acromegaly. Therefore, this study investigated the risk of fractures in Korean... -
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- Exploring the Association between Thyroid Function and Frailty: Insights from Representative Korean Data
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Lee YJ, Kim MH, Lim DJ, Lee JM, Chang SA, Lee J
- KMID: 2549266
- Endocrinol Metab.
- 2023 Dec;38(6):729-738.
- doi: 10.3803/EnM.2023.1769
Background: This study investigates the association between thyroid function and frailty in the old patients using representative data. Methods: The study was conducted using data from the Korea National Health and... -
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- Partial Deletion of Perk Improved High-Fat Diet-Induced Glucose Intolerance in Mice
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Lee J, Kim MJ, Moon S, Lim JY, Park KS, Jung HS
- KMID: 2549271
- Endocrinol Metab.
- 2023 Dec;38(6):782-787.
- doi: 10.3803/EnM.2023.1738
Although pancreatic endoplasmic reticulum kinase (PERK) is indispensable to beta cells, low-dose PERK inhibitor improved glucose- stimulated insulin secretion (GSIS) and hyperglycemia in diabetic mice. Current study examined if partial... -
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- Acromegaly and Bone: An Update
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Giustina A
- KMID: 2549258
- Endocrinol Metab.
- 2023 Dec;38(6):655-666.
- doi: 10.3803/EnM.2023.601
Since our discovery in 2006 that acromegaly is associated with an increased risk of vertebral fractures, many authors have confirmed this finding in both cross-sectional and prospective studies. Due to... -
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- Association between Smoking Status and the Risk of Hip Fracture in Patients with Type 2 Diabetes: A Nationwide Population-Based Study
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Lee SW, Heu JY, Kim JY, Kim J, Han K, Kwon HS
- KMID: 2549261
- Endocrinol Metab.
- 2023 Dec;38(6):679-689.
- doi: 10.3803/EnM.2023.1760
Background: Limited longitudinal evidence exists regarding the potential association between smoking status and hip fracture among individuals with type 2 diabetes. We investigated this association using large-scale, nationwide cohort data... -
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- Familial Correlation and Heritability of Hand Grip Strength in Korean Adults (Korea National Health and Nutrition Examination Survey 2014 to 2019)
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Ahn SH, Park EB, Seo S, Cho Y, Seo DH, Kim SH, Suh YJ, Hong S
- KMID: 2549264
- Endocrinol Metab.
- 2023 Dec;38(6):709-719.
- doi: 10.3803/EnM.2023.1740
Background: The onset and progression of sarcopenia are highly variable among individuals owing to genetic and environmental factors. However, there are a limited number of studies measuring the heritability of... -
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- AM1638, a GPR40-Full Agonist, Inhibited Palmitate- Induced ROS Production and Endoplasmic Reticulum Stress, Enhancing HUVEC Viability in an NRF2-Dependent Manner
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Hwang HJ, Kim JW, Yun S, Park MJ, Song E, Jang S, Jang A, Choi KM, Baik SH, Yoo HJ
- KMID: 2549269
- Endocrinol Metab.
- 2023 Dec;38(6):760-769.
- doi: 10.3803/EnM.2023.1774
Background: G protein-coupled receptor 40 (GPR40) is a key molecule in diabetes and fatty liver, but its role in endothelial dysfunction remains unclear. Our objective in this study was to... -
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- Higher Plasma Stromal Cell-Derived Factor 1 Is Associated with Lower Risk for Sarcopenia in Older Asian Adults
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Ji S, Kim K, Park SJ, Lee JY, Jung HW, Yoo HJ, Jang IY, Lee E, Baek JY, Kim BJ
- KMID: 2549263
- Endocrinol Metab.
- 2023 Dec;38(6):701-708.
- doi: 10.3803/EnM.2023.1783
Background: Despite the protective effects of stromal cell-derived factor 1 (SDF-1) in stimulating muscle regeneration shown in experimental research, there is a lack of clinical studies linking circulating SDF-1 concentrations... -
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- Comparative Analysis of Driver Mutations and Transcriptomes in Papillary Thyroid Cancer by Region of Residence in South Korea
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Lee J, Jeong S, Lee HY, Park S, Jeong M, Jo YS
- KMID: 2549265
- Endocrinol Metab.
- 2023 Dec;38(6):720-729.
- doi: 10.3803/EnM.2023.1758
Background: Radiation exposure is a well-known risk factor for papillary thyroid cancer (PTC). South Korea has 24 nuclear reactors in operation; however, no molecular biological analysis has been performed on... -
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- Incidence of Endocrine-Related Dysfunction in Patients Treated with New Immune Checkpoint Inhibitors: A Meta-Analysis and Comprehensive Review
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Yoo WS, Ku EJ, Lee EK, Ahn HY
- KMID: 2549268
- Endocrinol Metab.
- 2023 Dec;38(6):750-759.
- doi: 10.3803/EnM.2023.1785
Background: This study investigated the incidence of endocrine immune-related adverse events (irAEs) for recently developed immune checkpoint inhibitor (ICI) drugs. Methods: We collected studies on newly developed ICI drugs using PubMed/Medline,... -
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- Age-Dependent Association of Height Loss with Incident Fracture Risk in Postmenopausal Korean Women
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Lee C, Park HS, Rhee Y, Hong N
- KMID: 2549260
- Endocrinol Metab.
- 2023 Dec;38(6):669-678.
- doi: 10.3803/EnM.2023.1734
Background: Height loss is a simple clinical measure associated with increased fracture risk. However, limited data exists on the association between height loss and fracture risk in postmenopausal Korean women.... -
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- Phospholipase C-γ as a Potential Therapeutic Target for Graves’ Orbitopathy
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Roh TH, Chae MK, Ko JS, Kikkawa DO, Jang SY, Yoon JS
- KMID: 2549267
- Endocrinol Metab.
- 2023 Dec;38(6):739-749.
- doi: 10.3803/EnM.2023.1780
Background: Phospholipase C-γ (PLC-γ) plays a crucial role in immune responses and is related to the pathogenesis of various inflammatory disorders. In this study, we investigated the role of PLC-γ... -
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