- The study of pathogenesis of palmoplantar keratoderma
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Bang D, Lee SH, Lee HS, Shim W
- KMID: 2303620
- Korean J Dermatol.
- 1991 Jun;29(3):337-345.
We investigated the biochemiesl change of keratin by the methods of SDS-PAGE and Two-dimensional gel electrophoresis, and observed electron microscopic ultrestructural changes in five Unna-Thost palmoplantar keratoderma patients and two... -
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- 2DSpotDB: A Database for the Annotated Two-dimensional Polyacrylamide Gel Electrophoresis of Pathogen Proteins
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Kim DW, Yoo WG, Lee MR, Kim YJ, Cho SH, Lee WJ, Ju JW
- KMID: 2053277
- Genomics Inform.
- 2011 Dec;9(4):197-199.
The biological interpretation of two-dimensional (2D) gel electrophoresis experiments is a key step toward understanding the functions of biological systems. We here present a web-based integrated database, called 2DSpotDB, for... -
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- Separation of Tissue proteins in Transitional Cell Carcinoma of Bladder by Two-dimensional Electrophoresis
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Hong SJ, Ahn YS, Lee JM
- KMID: 2114874
- Korean J Urol.
- 1988 Aug;29(4):525-532.
The heterogeneous mixture of proteins present in high grade, invasive transitional cell carcinoma of bladder from thirteen patients were analysed by two-dimensional gel electrophoresis in comparison with normal bladder tissue.... -
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- Identification of Proteome Molecules by Proteomics Using Two-Dimensional Gel Electrophoresis and MALDI-TOF MS
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Song EJ, Lee KJ
- KMID: 2038543
- Korean J Infect Dis.
- 2001 Dec;33(6):470-476.
Genomic technologies have enabled rapid accumulation of information from complex biological systems over the last two decades. The complete DNA sequence is now known for many organism and the informational... -
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- The Analysis of Epidermal Proteins in Patients with Psoriasis by Two-Dimensional Gel Electrophoresis
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Lee DH, Lee KH, Park YK
- KMID: 2303030
- Korean J Dermatol.
- 2003 Feb;41(2):207-213.
BACKGROUND: Psoriasis is a common, chronic, recurrent, inflammatory disease of the skin characterized by circumscribed, erythematous, thick plaques covered by silvery white scales. Although many researchers are working hard on... -
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- Analysis of protein expression in Brucella abortus mutants with different growth rates by two-dimensional gel electrophoresis and LC-MS/MS peptide analysis
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Park WB, Im YB, Shim S, Yoo HS
- KMID: 2407621
- J Vet Sci.
- 2018 Mar;19(2):216-231.
- doi: 10.4142/jvs.2018.19.2.216
Brucella abortus is a bacterium that causes brucellosis and is the causative agent of worldwide zoonoses. Pathogenesis of the B. abortus infection is complicated, and several researchers have attempted to... -
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- Identification of a Marker Protein for Cardiac Ischemia and Reperfusion Injury by Two-Dimensional Gel Electrophoresis and Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
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Lee Y, Kim N, Kim H, Joo H, Kim Y, Jeong D, Cuong DV, Kim E, Hur DY, Park YS, Hong YG, Lee S, Chung J, Seog D, Han J
- KMID: 1611348
- Korean J Physiol Pharmacol.
- 2004 Aug;8(4):207-211.
The purpose of the present study was to evaluate the expression of cardiac marker protein in rabbit cardiac tissue that was exposed to ischemic preconditioning (IPC), or ischemiareperfusion injury (IR)... -
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- Two-dimensional gel electrophoresis and immunoblot analysis of Neospora caninum tachyzoites
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Lee EG, Kim JH, Shin YS, Shin GW, Kim YH, Kim GS, Kim DY, Jung TS, Suh MD
- KMID: 1120070
- J Vet Sci.
- 2004 Jun;5(2):139-145.
Identification of expressed protein profiles and antigenic determination are some of the most challenging aspects of proteomics. Two-dimensional gel electrophoresis (2-DE) combined with immunoblot analysis were employed to study the... -
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- Mass spectrometry based proteomic analysis of human stem cells: a brief review
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Choi MY, An YJ, Kim SH, Roh SH, Ju HK, Hong SS, Park JH, Cho KJ, Choi DW, Kwon SW
- KMID: 1091063
- Exp Mol Med.
- 2007 Dec;39(6):690-695.
Stem cells can give rise to various cell types and are capable of regenerating themselves over multiple cell divisions. Pluripotency and self-renewal potential of stem cells have drawn vast interest... -
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- Comparative Analysis of the Tear Protein Expression After Photorefractive Keratectomy Using Two-Dimensional Electrophoresis
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Chae JK, Park SP, Choi TH
- KMID: 2212319
- J Korean Ophthalmol Soc.
- 2009 May;50(5):762-768.
- doi: 10.3341/jkos.2009.50.5.762
PURPOSE:To investigate the change in the tear protein composition of patients who underwent refractive surgery. METHODS: Tear samples were collected before photorefrative keratectomy (PRK), on the first, the second, and the... -
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- Two-dimensional gel electrophoresis of Helicobacter pylori for proteomic analysis
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Jung TS, Kang SC, Choi YJ, Jeon BS, Park JW, Jung SA, Song JY, Choi SH, Park SG, Choe MY, Lee BS, Byun EY, Baik SC, Lee WK, Cho MJ, Youn HS, Ko GH, Rhee KH
- KMID: 2146883
- J Korean Soc Microbiol.
- 2000 Apr;35(2):97-108.
Two-dimensional gel electrophoresis (2-DE) is an essential tool of proteomics to analyse the entire set of proteins of an organism and its variation between organisms. Helicobacter pylori was tried to identify differences between... -
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- Proteomic Profiling of Human Small Cell Lung Cancer Cell Line NCI-H211
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Cho HY, Kim MK, Yoo YD, Ahn MJ, Jang JS
- KMID: 1972869
- Cancer Res Treat.
- 2003 Dec;35(6):489-496.
PURPOSE: Small cell lung cancer is one of the major causes of death from cancer worldwide. To explore the expressions of global protein in small cell lung cancer cells, a... -
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- Identification of CLP36 as a Tumor Antigen that Induces an Antibody Response in Pancreatic Cancer
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Hong SH
- KMID: 1743358
- Cancer Res Treat.
- 2005 Feb;37(1):71-77.
PURPOSE: Pancreatic cancer has a poor prognosis, due in part to the lack of an effective approach for its early detection. The identification of tumor antigens potentially provides a means... -
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- Reference Map of Soluble Proteins from Salmonella enterica Serovar Enteritidis by Two-Dimensional Electrophoresis
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Park MR, Lee EG, Kim YH, Jung TS, Shin YS, Shin GW, Cha HG, Kim GS
- KMID: 1089404
- J Vet Sci.
- 2003 Aug;4(2):143-149.
Protein identification by peptide mass fingerprinting using matrix-assisted laser desorption ionization time of fight (MALDI-TOF) mass spectrometry (MS) can analyze unambiguously identity of the spots from a 2-dimensional electrophoresis (2-DE)... -
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- Identification of New Proteins in Follicular Fluid from Mature Human Follicles by Direct Sample Rehydration Method of Two-Dimensional Polyacrylamide Gel Electrophoresis
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Lee HC, Lee SW, Lee KW, Lee SW, Cha KY, Kim KH, Lee S
- KMID: 1778506
- J Korean Med Sci.
- 2005 Jun;20(3):456-460.
- doi: 10.3346/jkms.2005.20.3.456
Human follicular fluid (HFF) includes various biologically active proteins which can affect follicle growth and oocyte fertilization. Thus far, these proteins from mature follicles in human follicular fluid have been... -
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- The Proteomics Approach to Find Biomarkers in Gastric Cancer
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Ryu JW, Kim HJ, Lee YS, Myong NH, Hwang CH, Lee GS, Yom HC
- KMID: 648901
- J Korean Med Sci.
- 2003 Aug;18(4):505-509.
- doi: 10.3346/jkms.2003.18.4.505
Gastric cancer is a very serious disease and is naturally resistant to many anticancer drugs. To reduce the mortality and improve the effectiveness of therapy, many studies have tried to... -
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- Proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry
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Ahn JY, Kim IY, Oh SJ, Hwang HS, Yi SS, Kim YN, Shin JH, Yoon YS, Seong JK
- KMID: 1707443
- Lab Anim Res.
- 2014 Jun;30(2):45-53.
- doi: 10.5625/lar.2014.30.2.45
Pig pancreas may be a therapeutic resource for human diabetic patients. However, this potential is hindered by a lack of knowledge of the molecular events of pig pancreas development. In... -
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- Identification of Proteins Differentially Expressed in the Conventional Renal Cell Carcinoma by Proteomic Analysis
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Hwa JS, Park HJ, Jung JH, Kam SC, Park HC, Kim CW, Kang KR, Hyun JS, Chung KH
- KMID: 1778505
- J Korean Med Sci.
- 2005 Jun;20(3):450-455.
- doi: 10.3346/jkms.2005.20.3.450
Renal cell carcinoma (RCC) is one of the most malignant tumors in urology, and due to its insidious onset patients frequently have advanced disease at the time of clinical presentation.... -
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- Proteomic analysis of pancreas in miniature pigs according to developmental stages using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry
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Yi SS, Kim IY, Oh SJ, Yeom HJ, Yeom SC, Hwang SY, Seong JK
- KMID: 2312113
- Lab Anim Res.
- 2014 Mar;30(1):1-7.
Organ transplantation is limited by the shortage of human organs. Many studies have sought to overcome this hurdle by using animal organs. Porcine organs, especially from miniature pigs, have been... -
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- Mitochondrial Aldehyde Dehydrogenase Precursor Protein and 3-hydroxy-3-methylglutaryl-coenzyme A synthase 2: Two-dimensional Electrophoretic Expressed Protein in the Liver of Acute Alcoholic Abuse
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Yoo SH
- KMID: 2082730
- Korean J Leg Med.
- 2009 May;33(1):65-69.
To study alcohol-related expressed proteins across postmortem livers, human liver tissues from two cadaveric subjects died of acute alcohol abuse and myocardialinfarct were compared. Liver tissues were separated by means... -
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