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Drug Effect and Generic Substitution

Kim KS, Song CH

  • KMID: 2338179
  • J Korean Geriatr Soc.
  • 2000 Sep;4(3):98-109.
No abstract available.
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Bioequivalence Test and Its Significance

Kim KH

Bioequivalence is defined as the absence of a significant difference in the rate and extent to which the active ingredient or active moiety in pharmaceutical equivalents or pharmaceutical alternatives becomes...
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Successful treatment with tacrolimus of refractory adult-onset Still's disease

Ohe M, Oku K, Kono M, Bohgaki T

No abstract available.
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Strategies for Switching Antipsychotics

Kim YH, Rhee CG

  • KMID: 2286835
  • Korean J Psychopharmacol.
  • 2005 May;16(3):187-196.
As novel antipsychotic agents are introduced, the needs for practical guidelines on switching medications is becoming increasingly important. Cross-tapering is generally the most acceptable methods of switching, although abrupt change...
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Establishment and Significance of Bioequivalence Recommendations for Individual Products-Drugs Acting on Circulatory System and Others

Bae SH, Zheng YF, Kwon MJ, Choi EJ, Bae SK

  • KMID: 2334541
  • J Korean Soc Clin Pharmacol Ther.
  • 2013 Jun;21(1):17-25.
Along with the enactment of a law separating the prescribing and dispensing of drugs in Korea in 2000, attempts at reducing medical expenses by generic substitution have been allowed since...
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A multicenter experience with generic mycophenolate mofetil conversion in stable liver transplant recipients

Kim JM, Kwon CH, Yun IJ, Lee KW, Yu HC, Suh KS, Joh JW, Cho BH

PURPOSE: Generic substitution of brand-name medications can lead to significant cost savings and is an accepted medical practice. This study evaluated clinical and safety outcomes among liver transplant recipients whose...
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Strategies for Early Non-response to Antipsychotic Drugs in the Treatment of Acute-phase Schizophrenia

Hatta K, Ito H

  • KMID: 2171123
  • Clin Psychopharmacol Neurosci.
  • 2014 Apr;12(1):1-7.
As a strategy for antipsychotic treatment of schizophrenia, monotherapy is clearly optimal when both effective and tolerated. When a patient fails to respond to an adequate dose of an antipsychotic,...
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The Effect of Tumor Necrosis Factor-Alpha Inhibitors on Uveitis in Patients with Ankylosing Spondylitis

Lee S, Park YJ, Lee JY

BACKGROUND: Tumor necrosis factor-alpha (TNF-α) inhibitors (TNFis), which are the main treatment for ankylosing spondylitis (AS), have been reported not only to reduce the incidence of anterior uveitis (AU) but...
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Entecavir to Telbivudine Switch Therapy in Entecavir-Treated Patients with Undetectable Hepatitis B Viral DNA

Kim DH, Choi JW, Seo JH, Cho YS, Won SY, Park BK, Jeon HH, Shin SY, Lee CK

PURPOSE: This study examined 2-year outcome of consecutive therapy using entecavir (ETV) followed by telbivudine (LdT) in subjects with undetectable hepatitis B virus (HBV) DNA level and normal alanine aminotransferase...
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Long-term efficacy of tenofovir disoproxil fumarate therapy after multiple nucleos(t)ide analogue failure in chronic hepatitis B patients

Kim HJ, Cho JY, Kim YJ, Gwak GY, Paik YH, Choi MS, Koh KC, Paik SW, Yoo BC, Lee JH

BACKGROUND/AIMS: The efficacy of tenofovir disoproxil fumarate (TDF) for the treatment of chronic hepatitis B (CHB) patients following prior treatment failure with multiple nucleos(t)ide analogues (NAs) is not well defined,...
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