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Randomized study between radical surgery and radiotherapy for the treatment of stage IB–IIA cervical cancer: 20-year update

Landoni F, Colombo A, Milani R, Placa F, Zanagnolo , Mangioni C

OBJECTIVE: Stage IB–IIA cervical carcinoma can be equally cured either by radical surgery or radiotherapy (RT). Albeit such policies show the same efficacy, they carry a different morbidity. This is...
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Statistical notes for clinical researchers: Chi-squared test and Fisher's exact test

Kim HY

No abstract available.
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Pathologic findings at risk-reducing salpingo-oophorectomy (RRSO) in germline BRCA mutation carriers with breast cancer: significance of bilateral RRSO at the optimal age in germline BRCA mutation carriers

Lee YJ, Lee SW, Kim KR, Jung KH, Lee JW, Kim YM

OBJECTIVE: Most BRCA1/2 carriers do not undergo risk-reducing salpingo-oophorectomy (RRSO) by the recommended age. This study aimed to find the incidence of precursor lesions and cancer after RRSO. METHODS: We retrospectively...
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Controlling endemic multidrug-resistant Acinetobacter baumannii in Intensive Care Units using antimicrobial stewardship and infection control

Cheon S, Kim MJ, Yun SJ, Moon JY, Kim YS

BACKGROUND/AIMS: Nosocomial infections caused by multidrug-resistant (MDR) Acinetobacter baumannii have become public-health problem. However, few studies have evaluated the control of endemic MDR A. baumannii in Intensive Care Units (ICUs)....
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Epidemiology of chronic thromboembolic pulmonary hypertension in Korea: results from the Korean registry

Park SY, Lee SM, Shin JW, Choi BW, Kim H, Lee JS, Lee SD, Park SS, Moon HS, Park YB

BACKGROUND/AIMS: The diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH) is difficult for numerous reasons and is related with a poor prognosis. In Korea, the incidence of CTEPH and its clinical...
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Angiotensin II type 1 receptor blockers as a first choice in patients with acute myocardial infarction

Lee JH, Bae MH, Yang DH, Park HS, Cho Y, Lee WK, Jeong MH, Kim YJ, Cho MC, Kim CJ, Chae SC, Korea Acute Myocardial Infarction Registry Investigators

BACKGROUND/AIMS: Angiotensin II type 1 receptor blockers (ARBs) have not been adequately evaluated in patients without left ventricular (LV) dysfunction or heart failure after acute myocardial infarction (AMI). METHODS: Between November...
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Risk factors and etiology of surgical site infection after radical neck dissection in patients with head and neck cancer

Park SY, Kim MS, Eom JS, Lee JS, Rho YS

BACKGROUND/AIMS: Surgical site infection (SSI) is a major complication after radical neck dissection (RND) in patients with head and neck cancer (HNC). We investigated the incidence, risk factors, and etiology...
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Evaluation of treatment response and tissue necrosis as prognostic indicators following neoadjuvant chemoradiotherapy in rectal cancer patients

Jung JH, An HJ, Kim HJ, Lee J, Lee KM, Kim SH, Cho HM, Shim BY

BACKGROUND/AIMS: The objective of this study was to assess the prognostic roles of treatment response and tissue necrosis after chemoradiotherapy (CRT) in locally advanced rectal cancer. METHODS: A total of 243...
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Advanced chronic kidney disease: a strong risk factor for Clostridium difficile infection

Kim SC, Seo MY, Lee JY, Kim KT, Cho E, Kim MG, Jo SK, Cho WY, Kim HK

BACKGROUND/AIMS: It has been suggested that chronic kidney disease (CKD) is a risk factor for Clostridium difficile infection (CDI) and is associated with increased mortality among patients infected with C....
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Relationship between metabolic syndrome and thyroid nodules in healthy Koreans

Shin J, Kim MH, Yoon KH, Kang MI, Cha BY, Lim DJ

BACKGROUND/AIMS: This study evaluated the relationship between thyroid nodules and metabolic syndrome (MS) and its components in apparently healthy Koreans. METHODS: We reviewed the records of 3,298 subjects with no noticeable...
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Early monitoring for detection of antituberculous drug-induced hepatotoxicity

Lee CM, Lee SS, Lee JM, Cho HC, Kim WS, Kim HJ, Ha CY, Kim HJ, Kim TH, Jung WT, Lee OJ

BACKGROUND/AIMS: We investigated the time of onset of antituberculous drug-induced hepatotoxicity (ADIH) and related characteristics. METHODS: Adult patients (n = 1,031) treated with first-line antituberculous drugs between February 2009 and January...
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Predictive factors of mortality within 30 days in patients with nonvariceal upper gastrointestinal bleeding

Lee YJ, Min BR, Kim ES, Park KS, Cho KB, Jang BK, Chung WJ, Hwang JS, Jeon SW

BACKGROUND/AIMS: Nonvariceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency that can be life threatening. This study evaluated predictive factors of 30-day mortality in patients with this condition. METHODS: A...
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Genetic analysis of ABCG2 and SLC2A9 gene polymorphisms in gouty arthritis in a Korean population

Kim YS, Kim Y, Park G, Kim SK, Choe JY, Park BL, Kim HS

BACKGROUND/AIMS: Gout is a common inf lammatory arthritis triggered by the crystallization of uric acid in the joints. Serum uric acid levels are highly heritable, suggesting a strong genetic component....
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Clinical efficacy of erlotinib, a salvage treatment for non-small cell lung cancer patients following gefitinib failure

Cho KM, Keam B, Kim TM, Lee SH, Kim DW, Heo DS

BACKGROUND/AIMS: The purpose of this study was to identify predictive factors for erlotinib treatment in non-small cell lung cancer (NSCLC) patients following gefitinib failure. METHODS: Forty-five patients with NSCLC who were...
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Analysis of factors affecting hemorrhagic diathesis and overall survival in patients with acute promyelocytic leukemia

Lee HJ, Kim DH, Lee S, Koh MS, Kim SY, Lee JH, Lee S, Oh SY, Han JY, Kim HJ, Kim SH

BACKGROUND/AIMS: This study investigated whether patients with acute promyelocytic leukemia (APL) truly fulfill the diagnostic criteria of overt disseminated intravascular coagulation (DIC), as proposed by the International Society on Thrombosis...
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Obstructive sleep apnea with excessive daytime sleepiness is associated with non-alcoholic fatty liver disease regardless of visceral fat

Yu JH, Ahn JH, Yoo HJ, Seo JA, Kim SG, Choi KM, Baik SH, Choi DS, Shin C, Kim NH

BACKGROUND/AIMS: Obstructive sleep apnea (OSA) is associated with an increased risk of obesity and non-alcoholic fatty liver disease (NAFLD), but it remains unclear whether the risk of NAFLD is independently...
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Temporal trends and in-hospital outcomes of primary percutaneous coronary intervention in nonagenarians with ST-segment elevation myocardial infarction

Kim JY, Jeong MH, Choi YW, Ahn YK, Chae SC, Hur SH, Hong TJ, Kim YJ, Seong IW, Chae IH, Cho MC, Yoon JH, Seung KB, Other Korea Acute Myocardial Infarction Registry Investigators

BACKGROUND/AIMS: Data regarding the outcomes of primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) in nonagenarians are very limited. The aim of the present study was to...
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Interatrial septal thickness as a marker of structural and functional remodeling of the left atrium in patients with atrial fibrillation

Lim HE, Na JO, Im SI, Choi CU, Kim SH, Kim JW, Kim EJ, Han SW, Rha SW, Park CG, Seo HS, Oh DJ, Hwang C

BACKGROUND/AIMS: There have been reports that interatrial septal (IAS) thickness is increased in patients with atrial fibrillation (AF). This study was performed to investigate whether IAS thickness determined by transthoracic...
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Trends in Helicobacter pylori eradication rates by first-line triple therapy and related factors in eradication therapy

Kim SE, Park MI, Park SJ, Moon W, Choi YJ, Cheon JH, Kwon HJ, Ku KH, Yoo CH, Kim JH, Lee GW, Song SE

BACKGROUND/AIMS: Trends in successful eradication of Helicobacter pylori using first-line triple therapy, consisting of a proton pump inhibitor, amoxicillin, and clarithromycin, have been understudied. We evaluated H. pylori eradication rates...
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The CD4 slope can be a predictor of immunologic recovery in advanced HIV patients: a case-control study

Kim KH, Yi J, Lee SH

BACKGROUND/AIMS: Advanced human immunodeficiency virus (HIV) infection, despite sustained viral suppression by highly active antiretroviral therapy (HAART), is a risk factor for poor immunologic recovery. However, some patients with advanced...
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