- Serotonin Modulates the Correlations between Obsessive-compulsive Trait and Heart Rate Variability in Normal Healthy Subjects: A SPECT Study with [ 123 I]ADAM and Heart Rate Variability Measurement
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Kuo CY, Chen KC, Lee IH, Tseng HH, Chiu NT, Chen PS, Yang YK, Chang WH
- KMID: 2530462
- Clin Psychopharmacol Neurosci.
- 2022 May;20(2):271-278.
- doi: 10.9758/cpn.2022.20.2.271
Objective: The impact of serotonergic system on obsessive-compulsive disorder (OCD) is well studied. However, the correlation between OC presentations and autonomic nervous system (ANS) is still unclear. Furthermore, whether the... -
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- The Clinical Outcomes of Different First-Line EGFR-TKIs Plus Bevacizumab in Advanced EGFR-Mutant Lung Adenocarcinoma
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Huang YH, Hsu KH, Chin CS, Tseng JS, Yang TY, Chen KC, Su KY, Yu SL, Chen JJ, Chang GC
- KMID: 2528213
- Cancer Res Treat.
- 2022 Apr;54(2):434-444.
- doi: 10.4143/crt.2021.671
Purpose The aim of this study was to investigate the efficacy of various epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) plus bevacizumab in advanced EGFR-mutant lung adenocarcinoma patients. Materials and Methods From... -
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- Positive Symptoms in Antipsychotic-naïve Schizophrenia are Associated with Increased Body Mass Index after Treatment
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Lin SH, Tseng HH, Tsai HC, Chi MH, Lee IH, Chen PS, Chen KC, Yang YK
- KMID: 2513401
- Clin Psychopharmacol Neurosci.
- 2021 Feb;19(1):155-159.
- doi: 10.9758/cpn.2021.19.1.155
Objective: Weight gain is an important risk factor for morbidity and mortality among patients with schizophrenia. We speculated that positive symptoms, related to dopaminergic hyperactivity and altered mesolimbic function, are... -
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- ALDH2 Gene: Its Effects on the Neuropsychological Functions in Patients with Opioid Use Disorder Undergoing Methadone Maintenance Treatment
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Lee PW, Wang TY, Chang YH, Lee SY, Chen SL, Wang ZC, Chen PS, Chu CH, Huang SY, Tzeng NS, Lee IH, Chen KC, Yang YK, Hong JS, Lu RB
- KMID: 2502135
- Clin Psychopharmacol Neurosci.
- 2020 Feb;18(1):136-144.
- doi: 10.9758/cpn.2020.18.1.136
Objective: Patients with opioid use disorder (OUD) have impaired attention, inhibition control, and memory function. The aldehyde dehydrogenase 2 (ALDH2 ) gene has been associated with OUD and ALDH2 gene... -
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- Altered Auditory P300 Performance in Parents with Attention Deficit Hyperactivity Disorder Offspring
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Chi MH, Chu CL, Lee IH, Hsieh YT, Chen KC, Chen PS, Yang YK
- KMID: 2464717
- Clin Psychopharmacol Neurosci.
- 2019 Nov;17(4):509-516.
- doi: 10.9758/cpn.2019.17.4.509
OBJECTIVE: Altered event-related potential (ERP) performances have been noted in attention deficit hyperactivity disorder (ADHD) patients and reflect neurocognitive dysfunction. Whether these ERP alterations and correlated dysfunctions exist in healthy... -
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- Increased Readmission Risk and Healthcare Cost for Delirium Patients without Immediate Hospitalization in the Emergency Department
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Ma IC, Chen KC, Chen WT, Tsai HC, Su CC, Lu RB, Chen PS, Chang WH, Yang YK
- KMID: 2428969
- Clin Psychopharmacol Neurosci.
- 2018 Nov;16(4):398-406.
- doi: 10.9758/cpn.2018.16.4.398
OBJECTIVE: Hospitalization of patients with delirium after visiting the emergency department (ED) is often required. However, the readmission risk after discharge from the ED should also be considered. This study... -
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- The Association of Acquired T790M Mutation with Clinical Characteristics after Resistance to First-Line Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor in Lung Adenocarcinoma
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Huang YH, Hsu KH, Tseng JS, Chen KC, Hsu CH, Su KY, Chen JJ, Chen HW, Yu SL, Yang TY, Chang GC
- KMID: 2424801
- Cancer Res Treat.
- 2018 Oct;50(4):1294-1303.
- doi: 10.4143/crt.2017.512
PURPOSE: The main objective of this study was to investigate the relationship among the clinical characteristics and the frequency of T790M mutation in advanced epidermal growth factor receptor (EGFR)–mutant lung... -
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- Intercalated Treatment Following Rebiopsy Is Associated with a Shorter Progression-Free Survival of Osimertinib Treatment
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Tseng JS, Yang TY, Chen KC, Hsu KH, Huang YH, Su KY, Yu SL, Chang GC
- KMID: 2424789
- Cancer Res Treat.
- 2018 Oct;50(4):1164-1174.
- doi: 10.4143/crt.2017.460
PURPOSE: Epidermal growth factor receptor (EGFR) T790M mutation serves as an important predictor of osimertinib efficacy. However, little is known about how it works among patients with various timings of... -
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- Holistic Consideration of Patients with Schizophrenia to Improve Medication Adherence and Outcomes
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Lee LT, Chen KC, Chang WH, Chen PS, Lee IH, Yang YK
- KMID: 2171043
- Clin Psychopharmacol Neurosci.
- 2015 Aug;13(2):138-143.
- doi: 10.9758/cpn.2015.13.2.138
Although several algorithms have been applied to treat patients with schizophrenia, their clinical use remains still limited, because most emphasize the prescription of antipsychotics. A new algorithm with a more... -
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