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Clinical Application of Overlapping Confidence Intervals for Monitoring Changes in Serial Clinical Chemistry Test Results

Cho J, Seo DM, Uh Y

BACKGROUND: Interpretation of changes in serial laboratory results is necessary for both clinicians and laboratories; however, setting decision limits is not easy. Although the reference change value (RCV) has been...
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Evaluation of Analytical Performance of an Automated Glycated Hemoglobin Analyzer, HLC-723 G11

Chung YN, Yun SG, Cho Y

BACKGROUND: Glycated hemoglobin (HbA(1c)) is a key biomarker for the monitoring of glycemic balance in patients with diabetes. The aim of this study was to evaluate the performance of a...
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Design and Laboratory Implementation of Web Application for Collaboratively Setting Reference Intervals

Jeon BR, Lee YW

BACKGROUND: Although the same equipment and reagents can be employed for inspecting identical samples, the setting and verification methods for the corresponding reference intervals differ from each other, and such...
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Use of Liquid Chromatography-Tandem Mass Spectrometry for Clinical Testing in Korean Laboratories: a Questionnaire Survey

Chae H, Cho SE, Park HD, Chun S, Lee YW, Yun YM, Song SH, Lee SG, Lee K, Song J, Lee SY, On behalf of the Clinical Mass Spectrometry Research Committee of Korean Society of Clinical Chemistry

BACKGROUND: The use of liquid chromatography-tandem mass spectrometry (LC-MS/MS) has substantially increased in clinical laboratories worldwide. To assess the status of clinical LC-MS/MS testing in Korean laboratories, a questionnaire survey...
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A Questionnaire Survey on General Status and Opinions about Clinical Mass Spectrometric Analysis in Korea (2018)

Cho SE, Chae H, Park HD, Chun S, Lee YW, Yun YM, Song SH, Lee SG, Lee K, Song J, Lee SY, On behalf of the Clinical Mass Spectrometry Research Committee of Korean Society of Clinical Chemistry

The Clinical Mass Spectrometry Research Committee (CMSRC), in affiliation with the Korean Society of Clinical Chemistry (KSCC), conducted a questionnaire survey on opinions about the general status of clinical mass...
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Comparison of Method Group Precision in Proficiency Testing of Clinical Chemistry Tests Before and After Two Major Changes: Reorganization of Proficiency Testing and Implementation of the Differential Benefit for the Quality of Laboratory Tests

Park H, Cho J

No abstract available.
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Iodine Deficiency in Neonates: Where Do We Stand After a Quarter Century of Initiating Iodization Programs?

Jafri L, Majid H, Ahmed S, Siddiqui I, Ghani F, Khan AH

An observational study was conducted at the Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, to assess the iodine status using the World Health Organization (WHO), United Nations...
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Annual Report on the External Quality Assessment Scheme for General Chemistry in Korea (2017)

Lee YW

In 2017, the clinical chemistry proficiency testing program consisted of 24 programs with the addition of the urine chemistry program in the Korean Association of External Quality Assessment Service. The...
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Usefulness of P(50,std) for the Diagnostic Work-up of Patients with Erythrocytosis

Shin SY

High oxygen-affinity hemoglobin (Hb) variants and a 2,3-diphosphoglycerate (2,3-DPG) deficiency could cause congenital (familial) erythrocytosis. High oxygen-affinity Hb variants and a 2,3-DPG deficiency might result in low tissue oxygen tension...
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Evaluation of the Vacuum Blood Collection Tube, V-Tube, a Domestic Product for Clinical Chemistry and Thyroid Hormone Assays

Jo SJ, Kim YS, Lee SG, Lee J

BACKGROUND: It is known that the blood collection tube used can cause fluctuations in laboratory test results. We compared test results obtained when blood was collected in V-tube (AB Medical,...
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Report on the External Quality Assessment Scheme for Hemoglobin A1c in Korea (2016–2017)

Jun SH, Lee K, Song J

As part of the clinical chemistry programs of the Korean Association of External Quality Assessment Service, we organized trials to conduct external quality assessment of hemoglobin A1c (HbA1c) in 2016...
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Evaluation of a fixed-dose combination of benazepril and pimobendan in dogs with congestive heart failure: a randomized non-inferiority clinical trial

King JN, Hirakawa A, Sonobe J, Otaki H, Sakakibara N, Seewald W, Forster S

A fixed-dose combination tablet of benazepril and pimobendan (Fortekor Plus; Elanco Animal Health) was tested in dogs with congestive heart failure (CHF) caused by myxomatous mitral valve disease (MMVD) in...
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Preclinical safety assessment of Angelica acutiloba using a 13-week repeated dose oral toxicity study in rats

Yun JW, Kwon E, Kim SH, You JR, Kim YS, Park IA, Kim HH, Che JH, Kang BC

Angelica acutiloba (AA), a Japanese species of Danggui, has been used worldwide as a traditional herbal medicine with several bioactivities including anti-diabetic, anti-allergic, anti-inflammatory, anti-tumor, and anti-obesity. However, there is...
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Performance Evaluation of the JEOL BioMajesty JCA-BM6010/C Automated Clinical Chemistry Analyzer

Kim HN, Ji M, Moon HW, Hur M, Yun YM

BACKGROUND: JEOL BioMajesty JCA-BM6010/C (JCA-BM6010/C, JEOL Ltd., Japan) is a recently developed ultra-compact automated clinical chemistry analyzer with a throughput of 1,200 tests per hour. Here, we present the first...
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Annual Report on the External Quality Assessment Scheme for Routine Clinical Chemistry in Korea (2016)

Lee YW, Jeon BR, Kim JG, Jun SH, Yun YM, Chun S, Song J, Min WK, Routine Clinical Chemistry Program, Korean Association of External Quality Assessment Service

In 2016, the clinical chemistry proficiency-testing program consisted of 21 programs, including the general chemistry program of the Korean Association of External Quality Assessment Service. The general chemistry program consisted...
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Quality Management of Clinical Chemistry Tests in Blood Center

Ihm C, Lim HS

The main goal of transfusion medicine is safe and appropriate blood transfusion in all situations. To accomplish this, it is essential to have a high level quality management system for...
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Proposal of Modified HIL-indices for Determining Hemolysis, Icterus and Lipemia Interference on the Beckman Coulter AU5800 Automated Platform

Lim YK, Cha YJ

BACKGROUND: The amount of interference due to hemolysis, bilirubin, and lipemia can be measured on the AU5800 autoanalyzer (Beckman Coulter, USA) by spectrophotometry. This is reported as semi-quantitative indices, specifically...
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Origins and History of Laboratory Medicine

Lee HJ, Oh SH, Chang CL

Medical diagnostics plays a significant role in clinical decisions. The first medical laboratory test to be developed was urine analysis, in which urine properties were analyzed for diagnosis. Urine analysis...
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Annual Report on the External Quality Assessment Scheme for Clinical Chemistry in Korea (2015)

Jun SH, Song J, Song WH, Clinical Chemistry Subcommittee, Korean Association of External Quality Assessment Service

The Clinical Chemistry Subcommittee of the Korean Association for External Quality Assessment Service conducted external quality assessments in 2015. This included general chemistry and blood gas measurements as part of...
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Two-Week Repeated Dose Toxicity of Atractylodis Rhizoma Alba in F344 Rats

Han HY, Yang YS, Kim SN, Han SC, Lee JH, Jeong JY, Roh HS, Seok JH, Lee JS, Kim JA, Min BS

This research is to estimate the toxicity of Atractylodis Rhizoma Alba (ARA) in F344 rats and to find a dose level for the 13 weeks toxicity study. A hot water...
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