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Protocatechuic Aldehyde Represses Proliferation and Migration of Breast Cancer Cells through Targeting C-terminal Binding Protein 1

Deng Y, Guo W, Li G, Li S, Li H, Li X, Niu B, Song M, Zhang Y, Xu Z, Li F

PURPOSE: C-terminal binding protein 1 (CtBP1) is a transcriptional co-repressor that is overexpressed in many cancers. CtBP1 transcriptionally represses a broad array of tumor suppressors, which promotes cancer cell proliferation,...
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Methyl-CpG Binding Protein 2 in Alzheimer Dementia

Kim B, Choi Y, Kim HS, Im HI

Despite decades of research on Alzheimer disease, understanding the complexity of the genetic and molecular interactions involved in its pathogenesis remains far from our grasp. Methyl-CpG Binding Protein 2 (MeCP2)...
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Suppressor of Variegation 3–9 Homolog 2, a Novel Binding Protein of Translationally Controlled Tumor Protein, Regulates Cancer Cell Proliferation

Kim AR, Sung JY, Rho SB, Kim YN, Yoon K

Suppressor of Variegation 3–9 Homolog 2 (SUV39H2) methylates the lysine 9 residue of histone H3 and induces heterochromatin formation, resulting in transcriptional repression or silencing of target genes. SUV39H1 and...
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The Prognostic Significance of Notch1 and Fatty Acid Binding Protein 7 (FABP7) Expression in Resected Tracheobronchial Adenoid Cystic Carcinoma: A Multicenter Retrospective Study

Xie M, Wu X, Zhang J, He C, Wei S, Huang J, Fu X, Gu Y

PURPOSE: Adenoid cystic carcinoma (ACC) of the trachea and bronchus is a rare tumor. Although MYB-NFIB oncogene fusion and Notch1 mutation have been identified in ACC, little is known about...
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Diagnosis of Liver Fibrosis With Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein (WFA-M2BP) Among Chronic Hepatitis B Patients

Jekarl DW, Choi H, Lee S, Kwon JH, Lee SW, Yu H, Kim M, Kim Y, Sung PS, Yoon SK

BACKGROUND: Wisteria floribunda agglutinin-positive Mac-2 binding protein (WFA-M2BP) is a protein with altered glycosylation that reacts with lectin, and was recently identified as a useful non-invasive biomarker for the diagnosis...
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Usefulness of Enhanced Liver Fibrosis, Glycosylation Isomer of Mac-2 Binding Protein, Galectin-3, and Soluble Suppression of Tumorigenicity 2 for Assessing Liver Fibrosis in Chronic Liver Diseases

Moon HW, Park M, Hur M, Kim H, Choe WH, Yun YM

BACKGROUND: Liver biopsies have been partially replaced by noninvasive methods for assessing liver fibrosis. We explored the usefulness of four novel biomarkers, enhanced liver fibrosis (ELF), glycosylation isomer of Mac-2...
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Mac-2 Binding Protein Glycosylation Isomer: Emerging Non-Invasive Serum Marker for Liver Fibrosis

Cho SY, Hur M

No abstract available.
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Poly(rC) binding protein 2 acts as a negative regulator of IRES-mediated translation of Hr mRNA

Kim JK, Kim I, Choi K, Choi JH, Kim E, Lee HY, Park J, Kim Yoon S

During the hair follicle (HF) cycle, HR protein expression is not concordant with the presence of the Hr mRNA transcript, suggesting an elaborate regulation of Hr gene expression. Here we...
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Cytokine-like Activity of Liver Type Fatty Acid Binding Protein (L-FABP) Inducing Inflammatory Cytokine Interleukin-6

Kim H, Gil G, Lee S, Kwak A, Jo S, Kim E, Nguyen TT, Kim S, Jhun H, Kim S, Kim M, Lee Y, Kim S

It has been reported that fatty acid binding proteins (FABPs) do not act only as intracellular mediators of lipid responses but also have extracellular functions. This study aimed to investigate...
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The Relevance of Women's Diseases, Jun Activation-domain Binding Protein 1 (JAB1) and p27(kip1)

Kim M, Kim TH, Lee HH

The Jun activation-domain binding protein 1 (Jab1) recognize a potential coactivator of activator protein 1 (AP-1) such as c-fos, c-jun transcription factor and the fifth subunit of the COP9 signalosome...
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Effect of IL-18 binding protein on hepatic ischemia-reperfusion injury induced by infrarenal aortic occlusion

Ozsoy M, Gonul Y, Bal A, Ozkececi Z, Celep RB, Adali F, Hazman O, Kocak A, Tosun M

PURPOSE: Severe local and systemic tissue damage called ischemia/reperfusion (IR) injury occurs during the period of reperfusion. Free oxygen radicals and proinflammatory cytokines are responsible for reperfusion injury. IL-18 binding...
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The Effects of Marathon Running on Retinol Binding Protein 4 and C-reactive Protein Levels in Healthy Middle-aged Korean Men

Chae J, Kim S, Lee J, Jeon JY

BACKGROUND: The purpose of this study was to investigate the effects of marathon running (42.195 km) on retinol binding protein4 (RBP4) and C-reactive protein (CRP) in healthy middle aged Korean...
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Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells

Kim YM, Song I, Seo YH, Yoon G

BACKGROUND: Enhanced lipogenesis plays a critical role in cell senescence via induction of expression of the mature form of sterol regulatory element binding protein 1 (SREBP1), which contributes to an...
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Association of Serum Adipocyte-Specific Fatty Acid Binding Protein with Fatty Liver Index as a Predictive Indicator of Nonalcoholic Fatty Liver Disease

Jeon WS, Park SE, Rhee EJ, Park CY, Oh KW, Park SW, Lee WY

BACKGROUND: Adipocyte-specific fatty acid-binding protein (A-FABP) is a cytoplasmic protein expressed in macrophages and adipocytes and it plays a role in insulin resistance and metabolic syndrome. Recently, the fatty liver...
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Regulation of Urea Transporters by Tonicity-responsive Enhancer Binding Protein

Jung JY, Kwon M, Kim J

Urea accumulation in the renal inner medulla plays a key role in the maintenance of maximal urinary concentrating ability. Urea transport in the kidney is mediated by transporter proteins that...
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Relationship between SNP A and P1763 Polymorphisms on Dystrobrevin Binding Protein 1(DTNBP1) Gene and Smooth Pursuit Eye Movement(SPEM) Abnormality in Korean Schizophrenic Patients

Lee CH, Park BL, Kim LH, Kim DH, Cho SH, Park JS, Kim IY, Lee IS, Seo HG, Byun KO, Kim BJ, Hahn KH, Kim KH, Shin TM, Shin HD, Woo SI

  • KMID: 2299947
  • Korean J Biol Psychiatry.
  • 2006 Nov;13(4):279-288.
OBJECTIVES: We investigated the association of SNP A and P1763 polymorphisms on dystrobrevin binding protein 1(DTNBP1) gene with smooth pursuit eye movement(SPEM) abnormality in Korean schizophrenic patients. METHODS: We measured SPEM...
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Effect of Dietary Fibers on Retinol Binding Protein (RBP, cRBP I, cRBPII) Gene Expression in Rats Fed High Fat Diet

Jo MW, Shin DS

  • KMID: 2269916
  • Korean J Nutr.
  • 2005 Dec;38(10):817-826.
Recently it has been reported that vitamin A and retinol binding proteins (RBPs) in blood and urine were changed in the condition of diabetes mellitus or hyperlipidemia. Fruits and vegetables...
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The Expression of Galectin-3, a Beta-Galactoside Binding Protein, in Dendritic Cells

Kim MH, Joo HG

BACKGROUND: Dendritic cells (DCs) are the most potent APCs (antigen-presenting cells) and play a critical role in immune responses. Galectin-3 is a biological lectin with a beta-galactoside binding affinity. Recently,...
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Renal Transport Proteins Involved in Urinary Concentrating Mechanism

Kim DU

  • KMID: 1654779
  • Korean J Pediatr.
  • 2004 May;47(5):480-484.
Renal tubule and vasa recta are arranged in complex but specific anatomic relationships and the production of a concentrated urine is achieved by countercurrent multiplication mechanism in the renal medulla....
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Antibody Responses to the Recombinant Circumsporozite Protein, Merozoite Surface Protein, and Duffy Binding Protein Antigens of Plasmodium vivax in Korea

Suh IB, Ma KR, Lim CS, Lee KN

  • KMID: 2239584
  • Korean J Lab Med.
  • 2003 Jun;23(3):190-198.
BACKGROUND: Plasmodium vivax circumsporozoite protein (CSP), merozoite surface protein (MSP) and Duffy binding protein (DBP) are functionally important conserved proteins and may have an important role in developing antigens. The...
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