Korean J Hepatol.  1999 Dec;5(4):332-337.

Hepatocellular Carcinoma with Severe Hypoglycemia: Involvement of Insulin-ike Growth Factor I, II and Insulin-ike Growth Factor Binding Proteins

• Kim SJ
• Yun BY
• Choi HC

Abstract

We report a case of hepatocellular carcinoma presented with severe hypoglycemia. Computerized tomography and ultrasonography revealed a massive bilateral tumor with portal vein thrombosis. The levels of IGF-I (113 ng/mL) and IGFBP- (815 ng/mL) measured in the plasma, were lower than normal range. There was strong immunoreactivity of IGF- and IGF-I in immunohistochemical stain of tumor cells.

Keyword

Hepatocellular carcinoma; Hypoglycemia; IGF; IGFBP

MeSH Terms

Carcinoma, Hepatocellular*
Carrier Proteins*
Fibrinogen*
Hypoglycemia*
Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor I
Plasma
Reference Values
Ultrasonography
Venous Thrombosis
Carrier Proteins
Fibrinogen
Insulin-Like Growth Factor Binding Proteins
Insulin-Like Growth Factor I