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Adverse effects of statin therapy and their treatment

Cheon DY, Jo SH

Statins are one of the most widely used drugs worldwide as first-line drugs for the treatment of hyperlipidemia and the prevention and treatment of cardiovascular diseases. Most of the side...
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Anti-inflammatory effects of colchicine on coronary artery disease

Park HJ

Inflammation plays a crucial role in the pathophysiology of coronary artery disease (CAD). Several types of sterile inflammation are mediated through the nucleotide-binding oligomerization domain-like receptor pyrin domain containing 3...
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Effects of physical activity on cardiovascular outcomes and mortality in Korean patients with diabetes: a nationwide population-based cohort study

Jung I, Moon SJ, Kwon H, Park SE, Han KD, Rhee EJ, Lee WY

Background: Since a sedentary lifestyle is considered a modifiable risk factor for cardiovascular disease (CVD), physical activity (PA) is recommended for type 2 diabetes mellitus (T2DM) patients to prevent CVD....
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Safety and efficacy of low-dose aspirin in patients with coronary artery spasm: long-term clinical follow-up

Choi BG, Kim KH, Rha SW

Background: Aspirin is known to aggravate coronary artery spasm (CAS) regardless of the dose (100–325 mg/day). However, it is unclear whether low-dose aspirin (LDA; 100 mg) has deleterious impacts on...
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Polygenic risk score: a useful clinical instrument for disease prediction and risk categorization

Yun JS

Genetic information is one of the essential components of precision medicine. Over the past decade, substantial progress has been made, such as low-cost, high-throughput genotyping arrays, advances in statistical techniques,...
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Association between reproductive aging and hypertension among Korean women

Kim E, Lee Y, Kim HC

Background: Although postmenopausal women are well known to have a high prevalence of hypertension, it is unclear whether menopause itself increases blood pressure independently from the known risk factors of...
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Indirect comparison of nonvitamin K oral anticoagulants and left atrial appendage occlusion

Kim SH, Park SY, Hwang SS

Background: Anticoagulation is important in atrial fibrillation (AF) patients to reduce the occurrence of thrombotic events. We evaluated the efficacy and safety of percutaneous left atrial appendage occlusion (LAAO) as...
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