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Antidepressants in Spine Surgery: A Systematic Review to Determine Benefits and Risks

Bayoumi AB, Ikizgul O, Karaali CN, Bozkurt S, Konya D, Toktas ZO

Antidepressant drugs can be advantageous in treating psychiatric and non-psychiatric illnesses, including spinal disorders. However, spine surgeons remain unfamiliar with the advantages and disadvantages of the use of antidepressant drugs...
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Effectiveness and Safety of Bupropion in Children and Adolescents with Depressive Disorders: A Retrospective Chart Review

Kweon K, Kim HW

OBJECTIVE: This study aimed to investigate the effectiveness and safety of bupropion extended-release for the treatment of depressive disorder in children and adolescents. METHODS: This was a 12-week, retrospective chart review...
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Combination of In Vivo [¹²³I]FP-CIT SPECT and Microdialysis Reveals an Antipsychotic Drug Haloperidol-induced Synaptic Dopamine Availability in the Rat Midbrain and Striatum

Park SH, Song YS, Moon BS, Lee BC, Park HS, Kim SE

Synaptic dopamine (DA) is mainly regulated by the presynaptic DA transporter (DAT). Single-photon emission computerized tomography (SPECT) with the DAT radiotracer [¹²³I]FP-CIT assesses changes in synaptic DA availability when endogenous...
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Augmentation of Aripiprazole versus Bupropion on Specific Symptoms of Depression in Older Adult Patients : A Post-Hoc, Multi-Center, Open-Label, Randomized Study

Jo S, Cheon E, Lee K, Koo B, Park Y, Lee J, Lee S, Sung H

OBJECTIVES: The purpose of this study was to compare aripiprazole versus bupropion augmentation therapy in older adult patients with major depressive disorder unresponsive to selective serotonin reuptake inhibitors(SSRIs). METHODS: This is...
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Metoprolol treatment of dual cocaine and bupropion cardiovascular and central nervous system toxicity

Richards J, Gould JB, Laurin EG, Albertson

Cardiovascular and central nervous system (CNS) toxicity, including tachydysrhythmia, agitation, and seizures, may arise from cocaine or bupropion use. We report acute toxicity from the concomitant use of cocaine and...
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Understanding the Mechanism of Action and Clinical Implications of Anti-Obesity Drugs Recently Approved in Korea

Kim KK

The Korean Ministry of Food and Drug Safety has approved three anti-obesity drugs for long-term management in the past decade. In addition, since 2019, bariatric surgery has been financially supported...
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Smoking Cessation Strategies Targeting Specific Populations

Chun EM

Quitting smoking helps smokers maintain their health and extend their lifespan by 10 or more years. Treatment strategies for smoking cessation should be tailored to individual smokers with special needs...
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Comparison of the Bupropion versus Aripiprazole Adjunctive Therapy for the Treatment of Female Depression : Post-Hoc Analyses from a Randomized Prospective Open-Label Multi-Center Study

Keum MS, Cheon EJ, Lee KH, Koo BH, Lee YJ, Park YW, Lee JH, Lee SJ, Sung HM

OBJECTIVES: The purpose of this study was to examine effects of adjunctive aripiprazole versus bupropion, on depressive symptoms of female depression. METHODS: Sixty six female patients with major depressive disorders were...
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Antidepressant Prescription Patterns in Bipolar Disorder: a Nationwide, Register-based Study in Korea

Yoon W, Shon SH, Hong Y, Joo YH, Lee JS

BACKGROUND: The role of antidepressants (ADs) in bipolar disorder is long-standing controversial issue in psychiatry. Many clinicians have used ADs as a treatment for bipolar depression, and the selection of...
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National Trends in Smoking Cessation Medication Prescriptions for Smokers With Chronic Obstructive Pulmonary Disease in the United States, 2007-2012

Kwak MJ, Kim J, Bhise V, Chung TH, Petitto GS

OBJECTIVES: Smoking cessation decreases morbidity and mortality due to chronic obstructive pulmonary disease (COPD). Pharmacotherapy for smoking cessation is highly effective. However, the optimal prescription rate of smoking cessation medications...
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Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review

Wang SM, Han C, Bahk WM, Lee SJ, Patkar AA, Masand PS, Pae CU

Randomized trials have shown that selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) have better safety profiles than classical tricyclic antidepressants (TCAs). However, an increasing number of studies,...
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Pharmacotherapy for Smoking Cessation in Patients with Schizophrenia

Kim SJ, Jung DU, Kim YN

Schizophrenia is a major chronic mental illness with various symptoms that is often accompanied by substance use disorders. Patients with schizophrenia have a higher smoking rate than the general population...
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Comparing the Effects of Bupropion and Escitalopram on Excessive Internet Game Play in Patients with Major Depressive Disorder

Nam B, Bae S, Kim SM, Hong JS, Han DH

OBJECTIVE: Several studies have suggested the efficacy of bupropion and escitalopram on reducing the excessive internet game play. We hypothesized that both bupropion and escitalopram would be effective on reducing...
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Tardive Dyskinesia Associated with Bupropion

Tuman TC, Çakır U, Yıldırım O, Camkurt MA

Present report describes a 46 year old male patient with a diagnosis of major depression who developed tardive dyskinesia during bupropion therapy. Our patient had no history of neuroleptic use...
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Effects of analgesics and antidepressants on TREK-2 and TRESK currents

Park H, Kim EJ, Han J, Han J, Kang D

TWIK-related K+ channel-2 (TREK-2) and TWIK-related spinal cord K+ (TRESK) channel are members of two-pore domain K+ channel family. They are well expressed and help to set the resting membrane...
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The Accompanying Changes in Brain Structure of a Remitted Depression Patient with the Bupropion Treatment

Hou YC, Lai CH

The impacts from the bupropion on the brain structures have seldom been mentioned in the literature. The bupropion is a kind of antidepressant with dual action in the norepinephrine and...
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Bupropion for Interferon-Alpha-Induced Depression in Patients with Hepatitis C Viral Infection: An Open-Label Study

Chen WC, Lai HC, Su WP, Palani M, Su KP

Interferon (IFN)-alpha therapy for chronic hepatitis C virus (HCV) infection is frequently associated with major depressive episodes. Bupropion, a commonly used antidepressant agent, has recently found to have strong anti-inflammatory...
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Pharmacotherapy for Obesity in Mood Disorders

Sohn I, Lee KH

The prevalence of obesity and overweight is increasing in mood disorder, and it is connected to an increased cardiovascular mortality. Because of them, treatment for obesity may be an essential...
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Effective Smoking-Cessation Strategies in Primary Care Setting

Chun EM

Smoking leads to nicotine addiction and serious health problems and smoking cessation can reduce the risk of developing smoking-related diseases and premature death. Smoking is a chronic disease that requires...
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Korean Medication Algorithm for Bipolar Disorder 2014: Depressive Episode

Seo JS, Bahk WM, Lee JG, Woo YS, Jeong JH, Wang HR, Kim MD, Sohn I, Shim SH, Min KJ, Jon DI, Shin YC, Yoon BH

  • KMID: 2287781
  • Korean J Psychopharmacol.
  • 2014 Apr;25(2):68-78.
OBJECTIVE: Since the Korean Medication Algorithm Project for Bipolar Disorder (KMAP-BP) was developed in 2002, the third revision of KMAP-BP was performed in 2014 in order to reflect the recent...
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