Ann Dermatol.  2015 Apr;27(2):239-241. 10.5021/ad.2015.27.2.239.

Preliminary Study of Intralesional Bleomycin Injection for the Treatment of Genital Warts

• Lee JY
• Kim CW
• Kim SS

• KMID: 2264828
• DOI: http://doi.org/10.5021/ad.2015.27.2.239

Abstract

No abstract available.

MeSH Terms

Bleomycin*
Condylomata Acuminata*
Bleomycin

Figure

• 

  Fig. 1 Clinical findings in patient #10. (A) A crusted, verrucous plaque (average dimensions, 22×40 mm) located on the penile shaft. (B) After the second intralesional bleomycin injection, the genital warts had nearly resolved, although mild erosion had developed. (C) Clearance of genital warts with hypopigmentation at 2 weeks after 4 treatment sessions of intralesional bleomycin injection.

Reference

1. Yanofsky VR, Patel RV, Goldenberg G. Genital warts: a comprehensive review. J Clin Aesthet Dermatol. 2012; 5:25–36.

2. Husseinzadeh N. Basic therapeutic principles and the strategy in the management of the external anogenital warts (condylomas): A review. J Clin Gynecol Obstet. 2013; 2:1–9.

3. Sterling JC, Handfield-Jones S, Hudson PM. British Association of Dermatologists. Guidelines for the management of cutaneous warts. Br J Dermatol. 2001; 144:4–11.

4. Gunter J. Genital and perianal warts: new treatment opportunities for human papillomavirus infection. Am J Obstet Gynecol. 2003; 189:3 Suppl. S3–S11.

5. Figueroa S, Gennaro AR. Intralesional bleomycin injection in treatment of condyloma acuminatum. Dis Colon Rectum. 1980; 23:550–551.

6. Munn SE, Higgins E, Marshall M, Clement M. A new method of intralesional bleomycin therapy in the treatment of recalcitrant warts. Br J Dermatol. 1996; 135:969–971.

7. Amer M, Diab N, Ramadan A, Galal A, Salem A. Therapeutic evaluation for intralesional injection of bleomycin sulfate in 143 resistant warts. J Am Acad Dermatol. 1988; 18:1313–1316.

8. Saitta P, Krishnamurthy K, Brown LH. Bleomycin in dermatology: a review of intralesional applications. Dermatol Surg. 2008; 34:1299–1313.

9. Yamamoto T. Bleomycin and the skin. Br J Dermatol. 2006; 155:869–875.