- The Changes of AQP1 and AQP4 Expression after Focal Cerebral Ischemia in Rats
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Noh SJ, Jo CM, Bae HR, Huh JT
- KMID: 1904527
- J Korean Neurosurg Soc.
- 2003 Oct;34(4):353-359.
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- Activated platelets induce secretion of interleukin-1beta, monocyte chemotactic protein-1, and macrophage inflammatory protein-1alpha and surface expression of intercellular adhesion molecule-1 on cultured endothelial cells
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Cha JK, Jeong MH, Bae HR, Han JY, Jeong SJ, Jin HJ, Lim YJ, Kim SH, Kim JW
- KMID: 1128623
- J Korean Med Sci.
- 2000 Jun;15(3):273-278.
- doi: 10.3346/jkms.2000.15.3.273
Atherosclerosis is an inflammatory disease. Platelet-endothelium interaction plays an important role in the pathophysiology of atherogenesis. We investigated the role of activated platelets for secretion of interleukin (IL)-1beta, monocyte chemotactic... -
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- Age-related regional difference of interleukin-1 expression in rat brain after lipopolysaccharide treatment
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Huh GY, Roh MS, Bae HR
- KMID: 1066502
- J Korean Med Sci.
- 2001 Feb;16(1):103-107.
- doi: 10.3346/jkms.2001.16.1.103
Aging is associated with altered immune responses including dysregulation of cytokine production. Of cytokines, interleukin-1 (IL-1) family has been primarily involved with central nervous system. To evaluate the age-related different... -
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- GD3 Accumulation in Cell Surface Lipid Rafts Prior to Mitochondrial Targeting Contributes to Amyloid-beta-induced Apoptosis
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Kim JK, Kim SH, Cho HY, Shin HS, Sung HR, Jung JR, Quan ML, Jiang DH, Bae HR
- KMID: 2157855
- J Korean Med Sci.
- 2010 Oct;25(10):1492-1498.
- doi: 10.3346/jkms.2010.25.10.1492
Neuronal apoptosis induced by amyloid beta-peptide (A beta) plays an important role in the pathophysiology of Alzheimer's disease (AD). However, the molecular mechanism underlying A beta-induced apoptosis remains undetermined. The... -
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- SLC9A6 -related developmental and epileptic encephalopathy with spike-and-wave activation in sleep: A case report
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Bae HR, Kim YO
- KMID: 2537692
- J Genet Med.
- 2022 Dec;19(2):100-104.
- doi: 10.5734/JGM.2022.19.2.100
The gene encoding solute carrier family 9 member 6 (SLC9A6) on Xq26.3 is associated with Christianson syndrome (CS) mimicking Angelman syndrome. In CS, developmental and epileptic encephalopathy (DEE) appears in... -
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- Awareness of good death, perception of life-sustaining treatment decision, and changes in nursing activities after decision to discontinue life-sustaining treatment among nurses in intensive care units at tertiary general hospitals
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Cho GY, Bae HR
- KMID: 2547395
- J Korean Crit Care Nurs.
- 2023 Oct;16(3):109-122.
- doi: 10.34250/jkccn.2023.16.3.109
Purpose : This study aims to explore nursing activities after the decision to discontinue life-sustaining treatment, awareness of a good death, and perception of life-sustaining treatment decisions among nurses in... -
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- Effect of Ethanol on the Regulation of Smooth Muscle Tone in Rat Aorta
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Suh DJ, Bae HR, Jung DK, Lee JH
- KMID: 1858589
- Korean Circ J.
- 2001 Feb;31(2):230-237.
- doi: 10.4070/kcj.2001.31.2.230
BACKGROUND AND OBJECTIVES: The aim of this study was to determine the effect of ethanol on the regulation of vascular tone. MATERIAL AND METHODS: Using rat aorta ring, isometric contraction... -
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- Febrile Seizure-induced Neuroexcitability in Immature Rat Hipocampus
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Choi BK, Hwang KG, Bae HR
- KMID: 1314294
- Korean J Pediatr.
- 2004 Sep;47(9):992-1001.
PURPOSE: To determine whether febrile seizure enhances neuroexcitability by altering synaptic transmission and whether febrile seizure-induced hyperexcitability leads to long-lasting neuronal death. METHODS: We investigated the expression of synaptic and... -
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- Circulating levels of interleukin-8 and vascular endothelial growth factor in patients with carotid stenosis
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Lee SH, Jeong MH, Bae HR, Jeong SJ, Jang JY, Lim YJ, Kim SH, Kim JW, Cha JK
- KMID: 648257
- J Korean Med Sci.
- 2001 Apr;16(2):198-203.
- doi: 10.3346/jkms.2001.16.2.198
Interleukin (IL)-8 and vascular endothelial growth factor (VEGF) are important factors that induce the migration and proliferation of endothelial cells, increase the vascular permeability, and the modulate chemotaxis of monocytes.... -
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- The Effects of Verapamil on Growth and Apoptosis of Keloid Fibroblast
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Park JM, Lee KC, Kim SK, Bae HR, Rha SH
- KMID: 2120040
- J Korean Soc Plast Reconstr Surg.
- 2005 Sep;32(5):625-634.
In this study, the effects of verapamil on growth rate, apoptosis, production of transforming growth factor (TGF-beta) and fibronectin were evaluated in keloid and normal human dermal fibroblasts. Both fibroblasts... -
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- Time-Dependent Expression Patterns of Cardiac Aquaporins Following Myocardial Infarction
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Zhang HZ, Kim MH, Lim JH, Bae HR
- KMID: 1786938
- J Korean Med Sci.
- 2013 Mar;28(3):402-408.
- doi: 10.3346/jkms.2013.28.3.402
Aquaporins (AQPs) are expressed in myocardium and the implication of AQPs in myocardial water balance has been suggested. We investigated the expression patterns of AQP subtypes in normal myocardium and... -
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- Cloning of mouse AQP-CD gene
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Jung JS, Kim JI, Oh SO, Park MY, Bae HR, Lee SH
- KMID: 1554555
- Korean J Physiol Pharmacol.
- 1997 Apr;1(2):195-200.
Water transport in highly-permeable membranes is facilitated by some specialized pathways, which are called aquaporins (AQP). AQP1 (AQP-CHIP) is the first recognized aquaporin identified from red cells and renal proximal tubules. Up until... -
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- The Effect of Topiramate on Status Epilepticus-Induced Neurotoxicity in Immature Mouse Brain
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Park SS, Bae HR, Hwang KG
- KMID: 2329571
- J Korean Child Neurol Soc.
- 2006 Nov;14(2):193-206.
PURPOSE:This study was performed to elucidate that status epilepticus (SE) induces long- term neuronal damages in an immature brain and to evaluate that topiramate (TPM) has a protective effect. METHODS:We investigated... -
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- The Role of Aquaporin-4 in Cerebral Edema Formation after Focal Cerebral Ischemia in Rats
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Song YJ, Bae HR, Ha SU, Huh JT
- KMID: 2339860
- J Korean Neurosurg Soc.
- 2007 Jan;41(1):30-38.
OBJECTIVE: To elucidate the role of aquaporin-4(AQP4) in cerebral edema formation, we studied the expression and subcellular localization of AQP4 in astrocytes after focal cerebral ischemia. METHODS: Cerebral ischemia were induced... -
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- Molecular analysis of AQP2 promoter. I. cAMP-dependent regulation of mouse AQP2 gene
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Park MY, Lee YH, Bae HR, Lee RH, Lee SH, Jung JS
- KMID: 1554132
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):157-164.
To determine molecular mechanisms of Aquaporin-CD (AQP2) gene regulation, the promoter region of the AQP2 gene was examined by transiently transfecting a promoter-luciferase reporter fusion gene into mouse renal collecting duct cell lines... -
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- Associations between Oxidized LDL to LDL Ratio, HDL and Vascular Calcification in the Feet of Hemodialysis Patients
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An WS, Kim SE, Kim KH, Bae HR, Rha SH
- KMID: 1778150
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S115-S120.
- doi: 10.3346/jkms.2009.24.S1.S115
Cardiovascular mortality is associated with vascular calcification (VC) in hemodialysis (HD) patients. The present study was designed to find factors related with medial artery calcification on the plain radiography of... -
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- Elevated Levels of alpha-Synuclein Oligomer in the Cerebrospinal Fluid of Drug-Naive Patients with Parkinson's Disease
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Park MJ, Cheon SM, Bae HR, Kim SH, Kim JW
- KMID: 2179007
- J Clin Neurol.
- 2011 Dec;7(4):215-222.
- doi: 10.3988/jcn.2011.7.4.215
BACKGROUND AND PURPOSE: The detection of alpha-synuclein in the body fluids of patients with synucleinopathy has yielded promising but inconclusive results, in part because of conformational changes of alpha-synuclein in... -
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- Stimulation of Cl- secretion by AlF4- and vanadate in T84 cells
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Hwang TH, Jung JS, Bae HR, Yun I, Lee SH
- KMID: 644842
- J Korean Med Sci.
- 1994 Dec;9(6):497-504.
- doi: 10.3346/jkms.1994.9.6.497
We investigated the mechanism of Cl- secretion by fluoroaluminate(AlF4-) and sodium orthovanadate(vanadate) using the human colonic T84 cell line. T84 cell monolayers grown on collagen-coated filters were mounted in Ussing... -
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- The Effects of Anti-keloid Drugs on the Expressions of Fibronectin, Transforming Growth Factor-beta and Transforming Growth Factor-beta Receptor in Keloid Fibroblast
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Park JM, Lee MH, Lee KC, Kim SK, Bae HR, Rha SH
- KMID: 2334706
- J Korean Soc Aesthetic Plast Surg.
- 2005 Sep;11(2):229-236.
Keloids represent a dysregulated response to cutaneous wounding that results in an excessive deposition of extracellular matrix. However, the molecular mechanisms underlying this pathologic deposition of extracellular matrix still remain... -
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- Localization of aquaporin-3 in mouse placenta and its role
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Kim HJ, Na YJ, Kim KH, Lee DH, Kim HG, Jo MS, Jung JY, Quan ML, Bae HR, Choi OH
- KMID: 1474934
- Korean J Obstet Gynecol.
- 2009 Aug;52(8):803-814.
OBJECTIVE: Aquaporin (AQP) 3 is a small integral membrane protein that functions as a facilitated transporter of water and glycerol. To elucidate a role of AQP3 in placenta, changes in... -
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