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Protective effect of chlorophyllremoved ethanol extract of Lycium barbarum leaves against nonalcoholic fatty liver disease

Lee H, Bae EY, Kim KA, Ly SY

Purpose: This study was conducted to establish whether an ethanol extract of Lycium barbarum leaves (LLE) and an ethanol extract of Lycium barbarum leaves from which chlorophyll has been removed,...
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A Measles Outbreak in a Local Children’s Hospital in Korea, 2019

So H, Kim KM, Bae EY, Cho EY

A measles outbreak with 20 confirmed cases occurred at a local children’s hospital in Daejeon from March 28 to April 21, 2019. The index patient was a 7-month-old girl with...
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EBV Associated Lymphomatoid Granulomatosis in 18-Year-Old Male: A Case Report

Jung ES, Bae EY, Roh EJ, Chung EH, You SK, Kim JM, Kim M, Lim YJ

Lymphomatoid granulomatosis (LYG) is an Epstein-Barr virus (EBV)-associated lymphoproliferative disease. It is considered a rare entity in pediatric patients. An adolescent male with lobar consolidation suspected of having pneumonia was...
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Anti-inflammatory effects of the ethanol fraction of Spiraea prunifolia var. simpliciflora in RAW 264.7 cells

Suhr J, Lee H, Kim S, Lee SJ, Bae EY, Ly SY

Purpose: Natural medicinal plant extracts have recently attracted attention as health beneficial foods and potential therapeutic agents for prevention of various diseases. This study was undertaken to measure the anti-inflammatory...
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First Case of Peroxisomal D-bifunctional Protein Deficiency with Novel HSD17B4 Mutations and Progressive Neuropathy in Korea

Bae EY, Yi Y, Lim HH, Lee JM, Lee B, Kim SY, Kim YM

Peroxisomal D-bifunctional protein (DBP), encoded by the HSD17B4 gene, catalyzes β-oxidation of very long chain fatty acids (VLCFAs). The deficiency of this peroxisomal enzyme leads to the accumulation of VLCFAs,...
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Anti-inflammatory effects of fruit and leaf extracts of Lycium barbarum in lipopolysaccharide-stimulated RAW264.7 cells and animal model

Bae SM, Kim JE, Bae EY, Kim KA, Ly SY

PURPOSE: Medicinal herbs have recently attracted attention as health beneficial foods and source materials for drug development. Recent studies have demonstrated that extracts of Lycium's fruits and roots have a...
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Anti-inflammatory effect of Lycium barbarum on polarized human intestinal epithelial cells

Lee SR, Hwang HJ, Yoon JG, Bae EY, Goo KS, Cho SJ, Cho JA

BACKGROUND/OBJECTIVES: Inflammatory Bowel Disease (IBD) has rapidly escalated in Asia (including Korea) due to increasing westernized diet patterns subsequent to industrialization. Factors associated with endoplasmic reticulum (ER) stress are demonstrated...
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Antioxidant activity of ethanol extract of Lycium barbarum's leaf with removal of chlorophyll

Kim JE, Bae SM, Nam YR, Bae EY, Ly SY

PURPOSE: The aim of this study was to estimate the antioxidant activities of 50%, 70%, and 100% ethanol extracts of Lycium barbarum leaf and chlorophyll removal extract. METHODS: The antioxidant activities...
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Clinical Features and Prognosis of Invasive Pulmonary Aspergillosis in Korean Children with Hematologic/Oncologic Diseases

Han SB, Kim SK, Bae EY, Lee JW, Yoon JS, Chung NG, Cho B, Jeong DC, Kang JH, Kim HK, Lee DG, Lee HS, Im SA

Invasive pulmonary aspergillosis (IPA) is the most frequent form of invasive fungal diseases in immunocompromised patients. However, there are only a few studies on IPA in immunocompromised children in Korea....
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Use of intravenous immunoglobulin in a disseminated varicella infection in an immunocompromised child

Kim JH, Kwon DH, Bae EY, Han SB, Lee JW, Chung NG, Jeong DC, Cho B, Kang JH, Kim HK

  • KMID: 2353165
  • Korean J Pediatr.
  • 2014 Aug;57(8):370-373.
Varicella-zoster virus infection can lead to severe illness in immunocompromised patients. Further the mortality rate of disseminated varicella infection is extremely high particularly in immunocompromised children. We report a case...
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Neonatal Meningoencephalitis caused by Herpes Simplex Virus Type 2

Kim DE, Pae R, Bae EY, Han JY, Han SB, Jeong DC, Lee IG, Kang JH

  • KMID: 1720819
  • Korean J Pediatr Infect Dis.
  • 2014 Aug;21(2):150-156.
Despite its rare occurrence, early diagnosis and appropriate treatment for neonatal herpes simplex virus infection are mandatory due to its high morbidity and mortality. In Korea, there has been no...
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Pertussis Seroprevalence in Korean Adolescents and Adults Using Anti-Pertussis Toxin Immunoglobulin G

Lee SY, Han SB, Bae EY, Kim JH, Kang JH, Park YJ, Ma SH

This study was conducted to evaluate age-specific seroprevalence of pertussis in Korea and to formulate a strategy to prevent and reduce the incidence of pertussis. Residual serum samples of healthy...
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Pulmonary hemorrhage in pediatric lupus anticoagulant hypoprothrombinemia syndrome

Kim JS, Kim MJ, Bae EY, Jeong DC

Lupus anticoagulant-hypoprothrombinemia syndrome (LAHPS), a very rare disease that is caused by the presence of antifactor II antibodies, is usually counterbalanced by the prothrombotic effect of lupus anticoagulant (LAC). Patients...
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A Case of Macrophage Activation Syndrome Developed in Female Adolescent with Systemic Lupus Erythematosus

Keum SW, Kim MJ, Bae EY, Han SB, Chung NG, Jeong DC, Kang JH

Macrophage activation syndrome (MAS) is a severe complication in patients with autoimmune disease. We should consider MAS in patients with autoimmune disease, who present with newly developed fever, and MAS...
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Risk Factors Associated with Respiratory Virus Detection in Infants Younger than 90 Days of Age

Eem YJ, Bae EY, Lee JH, Jeong DC

  • KMID: 1705183
  • Korean J Pediatr Infect Dis.
  • 2014 Apr;21(1):22-28.
PURPOSE: This study aimed at determining the detection rate of respiratory viruses and at investigating the risk factors associated with respiratory virus detection in young infants. METHODS: From September 2011 to...
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Liver abscess due to Klebsiella pneumoniae in a healthy 12-year-old boy

Yoon DH, Jeon YJ, Bae EY, Jeong DC, Kang JH

Pyogenic liver abscess (PLA) is rare in healthy children. We report a case of PLA in an immunocompetent 12-year-old boy. Percutaneous catheter drainage was performed for the abscess. In addition,...
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The Clinical Characteristics of Influenza B Infection during the 2011-2012 Influenza Season

Kim MS, Sung HW, Bae EY, Han SB, Jeong DC, Kang JH

  • KMID: 2279014
  • Korean J Pediatr Infect Dis.
  • 2013 Aug;20(2):89-97.
PURPOSE: This retrospective study was performed to identify the clinical characteristics of influenza B infection and compare to influenza A infection. METHODS: Medical records of patients diagnosed with influenza using a...
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A Functional Polymorphism in the CHRNA3 Gene and Risk of Chronic Obstructive Pulmonary Disease in a Korean Population

Lee JY, Yoo SS, Kang HG, Jin G, Bae EY, Choi YY, Choi JE, Jeon HS, Lee J, Lee SY, Cha SI, Kim CH, Park JY

A genome-wide association study has identified the 15q25 region as being associated with the risk of chronic obstructive pulmonary disease (COPD) in Caucasians. This study intended as a confirmatory assessment...
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Polymorphisms in Apoptosis-Related Genes and TP53 Mutations in Non-Small Cell Lung Cancer

Bae EY, Lee EJ, Kang HG, Lee SY, Jin G, Lee WK, Choi JE, Jeon HS, Lim JO, Lee EB, Park JY

Apoptosis plays an essential role in the elimination of mutated or transformed cells from the body. Therefore, polymorphisms of apoptosis-related genes may lead to an alteration in apoptotic capacity, thereby...
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Macrophage Activation Syndrome as the Extreme Form of Kawasaki Disease

Park HJ, Cho YJ, Bae EY, Choi UY, Lee SY, Jeong DC, Lee KY, Kang JH

  • KMID: 2072435
  • Korean J Pediatr Infect Dis.
  • 2010 Dec;17(2):177-181.
Few cases of macrophage activation syndrome (MAS) or reactive hemophagocytic lymphohistiocytosis (HLH) during the acute febrile phase of Kawasaki disease (KD) have been reported. We report on a case of...
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