- Colorectal Cancer and Prostaglandin
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Chang WK
- KMID: 1626393
- J Korean Soc Coloproctol.
- 2003 Feb;19(1):52-59.
The possibility for cyclooxygenase (COX) inhibitors in colorectal cancer prevention and theraphy is evident from epidemiologic data (reduction of colorectal cancer in nonsteroidal anti-inflammatory drugs (NSAIDs) users), animal experiments (nude... -
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- Modifying Effect of Indole-3-carbinol on the Rat Colon Carcinogenesis
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Jo H, Han BS, Kang JS, Jang DD, Kim K, Ahn B, Kim DJ
- KMID: 2114701
- Lab Anim Res.
- 2010 Dec;26(4):339-343.
- doi: 10.5625/lar.2010.26.4.339
Indole-3-carbinol (I3C) found in various cruciferous vegetables has been shown to exert anti-carcinogenic activity in several target organs. Our study was conducted to assess the modifying effect of I3C on... -
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- Dietary zinc inhibits the formation of colonic preneoplastic lesion induced by azoxymethane and dextran sodium sulfate in mice
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Park H, Kim DY, Kang BS, Yoon JS, Jeong JH, Nam SY, Yun YW, Kim JS, Lee BJ
- KMID: 1435822
- Korean J Vet Res.
- 2012 Jun;52(2):115-124.
Colorectal cancer (CRC) is one of the leading causes of cancer death in western countries or in the developed countries. Zinc intake has been associated with decreased risk of CRC.... -
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- Effects of Selenium on Colon Carcinogenesis Induced by Azoxymethane and Dextran Sodium Sulfate in Mouse Model with High-Iron Diet
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Kim JH, Hue JJ, Kang BS, Park H, Nam SY, Yun YW, Kim JS, Lee BJ
- KMID: 2391852
- Lab Anim Res.
- 2011 Mar;27(1):9-18.
Selenium (Se) is known to prevent several cancers while the relationship between high iron and the risk of colorectal cancer is controversial. To investigate the effects of Se in colon... -
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- Dietary Selenium Supplement Prevents Colon Carcinogenesis Induced by Azoxymethane and Dextran Sodium Sulfate in ICR Mice
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Kim JH, Hue JJ, Kang BS, Park H, Nam SY, Yun YW, Kim JS, Jeong JH, Lee BJ
- KMID: 2312080
- Lab Anim Res.
- 2010 Sep;26(3):293-300.
The role of selenium (Se) in modulating colon carcinogenesis induced by azoxymethane (AOM) followed by dextran sodium sulfate (DSS) was investigated in mice. Five-week old ICR mice were fed on... -
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- Chemopreventive effect of alpha-viniferin in azoxymethane-induced mouse colorectal tumor and Caco-2 cells
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Kwak DH, Shin SK, Youm SY, Kim TW, Kim Y, Ahn B
- KMID: 2286283
- J Biomed Res.
- 2015 Jun;16(2):60-66.
- doi: 10.12729/jbr.2015.16.2.060
alpha-Viniferin (AVF), a trimer of resveratrol, is known to have an anti-inflammatory effect via inhibition of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS). It has been reported that up-regulated... -
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- Açaà Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice
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Choi YJ, Choi YJ, Kim N, Nam RH, Lee S, Lee HS, Lee HN, Surh YJ, Lee DH
- KMID: 2412191
- Gut Liver.
- 2017 Mar;11(2):243-252.
- doi: 10.5009/gnl16068
BACKGROUND/AIMS: The aim of this study was to investigate the protective effect of açaà against azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer development. METHODS: The effect of açaà on tumorigenesis was... -
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- Effect of vitamin C on azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colitis-associated early colon cancer in mice
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Jeon HJ, Yeom Y, Kim YS, Kim E, Shin JH, Seok PR, Woo MJ, Kim Y
- KMID: 2407806
- Nutr Res Pract.
- 2018 Apr;12(2):101-109.
- doi: 10.4162/nrp.2018.12.2.101
BACKGROUND/OBJECTIVES: The objective of this study was to investigate the effects of vitamin C on inflammation, tumor development, and dysbiosis of intestinal microbiota in an azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced... -
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- Effects of luteolin on chemical induced colon carcinogenesis in high fat diet-fed obese mouse
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Park JE, Kim E
- KMID: 2410321
- J Nutr Health.
- 2018 Feb;51(1):14-22.
- doi: 10.4163/jnh.2018.51.1.14
PURPOSE: Colorectal cancer, which is one of the most commonly diagnosed cancers in developing and developed countries, is highly associated with obesity. The association is largely attributed to changes to... -
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- Effect of iron overload with ascorbic acid on experimental colon carcinogenesis in mice
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Ahn TH, Kim SJ, Jeong JH, Nam SY, Yun YW, Lee BJ
- KMID: 2405357
- J Biomed Transl Res.
- 2017 Dec;18(4):136-141.
- doi: 10.12729/jbtr.2017.18.4.136
Excessive iron can promote the production of free radicals, thereby leading to harmful effects on cancer and aging. Ascorbic acid is not only an antioxidant but also a co-factor of... -
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- Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model
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Song CH, Kim N, Sohn SH, Lee SM, Nam RH, Na HY, Lee DH, Surh YJ
- KMID: 2427459
- Gut Liver.
- 2018 Nov;12(6):682-693.
- doi: 10.5009/gnl18221
BACKGROUND/AIMS: Intestinal barrier dysfunction is a hallmark of inflammatory bowel diseases (IBDs) such as ulcerative colitis. This dysfunction is caused by increased permeability and the loss of tight junctions in... -
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- Near-Infrared Fluorescence Imaging Using a Protease-Specific Probe for the Detection of Colon Tumors
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Yoon SM, Myung SJ, Ye BD, Kim IW, Lee NG, Ryu YM, Park K, Kim K, Kwon IC, Park YS, Park CS, Moon DH, Kim DH, Do MY, Byeon JS, Yang SK, Kim JH
- KMID: 2167255
- Gut Liver.
- 2010 Dec;4(4):488-497.
BACKGROUND/AIMS: Early tumor detection is crucial for the prevention of colon cancer. Near-infrared fluorescence (NIRF) imaging using a target-activatable probe may permit earlier disease detection. Matrix metalloproteinases (MMPs) participate in... -
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- Suppressive Effect of Zinc on the Formation of Colonic Preneoplastic Lesions in the Mouse Fed High Levels of Dietary Iron
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Park H, Kang BS, Kim DY, Yoon JS, Jeong JH, Nam SY, Yun YW, Kim JS, Lee BJ
- KMID: 2052550
- Toxicol Res.
- 2012 Mar;28(1):39-49.
We investigated the effect of zinc on the formation of colonic aberrant crypt foci induced by azoxymethane (AOM) followed by dextran sodium sulfate (DSS) in mice with high iron diet... -
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