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Quantitative Assessment of Global and Regional Air Trappings Using Non-Rigid Registration and Regional Specific Volume Change of Inspiratory/Expiratory CT Scans: Studies on Healthy Volunteers and Asthmatics

Lee E, Seo JB, Lee HJ, Chae EJ, Lee SM, Oh SY, Kim N

OBJECTIVE: The purpose of this study was to compare air trapping in healthy volunteers with asthmatics using pulmonary function test and quantitative data, such as specific volume change from paired...
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Redistributed Regional Ventilation after the Administration of a Bronchodilator Demonstrated on Xenon-Inhaled Dual-Energy CT in a Patient with Asthma

Goo HW, Yu J

We report here on the redistributed regional ventilation abnormalities after the administration of a bronchodilator and as seen on xenon-inhaled dual-energy CT in a patient with asthma. The improved ventilation...
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Airway Responsiveness to Inhaled Aspirin is Influenced by Airway Hyperresponsiveness in Asthmatic Patients

Kim S, Choi IS, Kim YJ, Kim CS, Han ER, Park DJ, Kim DE

BACKGROUND/AIMS: Many patients with aspirin-induced asthma have severe methacholine airway hyperresponsiveness (AHR), suggesting a relationship between aspirin and methacholine in airway response. This study was performed to determine whether methacholine...
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Acute Effects of Asian Dust Events on Respiratory Symptoms and Peak Expiratory Flow in Children with Mild Asthma

Yoo Y, Choung JT, Yu J, Kim DK, Koh YY

The aim of this study was to investigate the possible adverse effects of Asian dust events on respiratory health in asthmatic children. Fifty-two children with mild asthma were studied for...
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Airways are More Reactive to Histamine than to Methacholine in Patients with Mild Airway Hyperresponsiveness, Regardless of Atopy

Choi IS, Lee S, Kim DH, Chung SW, Lee YC, Cho JY, Lee WJ

BACKGROUND: The airway muscles from allergen-sensitized animals in vitro show a heightened response to histamine, but not to carbachol. This study investigated whether the airway responsiveness to histamine in...
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Severe Airway Hyperresponsiveness in School-aged Boys with a High Body Mass Index

Jang AS, Lee JH, Park SW, Shin MY, Kim DJ, Park CS

BACKGROUND: An association between obesity and asthma has been reported. The prevalence of airway hyperresponsiveness (AHR), results of skin prick tests, body mass index (BMI), and asthma symptoms were...
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Effects of Air Pollutants on Childhood Asthma

Kim JH, Kim JK, Son BK, Oh JE, Lim DH, Lee KH, Hong YC, Cho SI

Epidemiologic studies have suggested the association between environmental exposure to volatile organic compounds (VOCs) and polycyclic aromatic hydrocarbons (PAHs) and the increased risk of incurring asthma. Yet there is little...
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Asthmatic Airway Inflammation is More Closely Related to Airway Hyperresponsiveness to Hypertonic Saline than to Methacholine

Choi IS, Hong SN, Lee YK, Koh YI, Jang AS, Lee HC

  • KMID: 1106140
  • Korean J Intern Med.
  • 2003 Jun;18(2):83-88.
BACKGROUND: Airway hyperresponsiveness (AHR) to direct stimuli, such as methacholine (MCh), is observed not only in asthma but other diseases. AHR to indirect stimuli is suggested to be more specific...
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Peak Expiratory Flow Rate Underestimates Severity of Airflow Obstruction in Acute Asthma

Choi IS, Koh YI, Lim H

  • KMID: 759607
  • Korean J Intern Med.
  • 2002 Sep;17(3):174-179.
BACKGROUND: Several investigators have demonstrated a considerable disagreement between FEV1 and PEFR to assess the severity of airflow obstruction. The purpose of this study was to examine whether the...
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Relationship Between Sputum Inflammatory Markers and Osmotic Airway Hyperresponsiveness During Induction of Sputum in Asthmatic Patients

Jang AS, Choi IS

Hypertonic saline aerosols are being used increasingly for bronchial provocation testing and induction of sputum. The aims of this study were to assess the response to challenge with 3% hypertonic...
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