- Metabolism-Centric Overview of the Pathogenesis of Alzheimer's Disease
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Kang S, Lee YH, Lee JE
- KMID: 2419103
- Yonsei Med J.
- 2017 May;58(3):479-488.
- doi: 10.3349/ymj.2017.58.3.479
Alzheimer's disease (AD) is a degenerative brain disease and the most common cause of dementia. AD is characterized by the extracellular amyloid beta (Aβ) plaques and intraneuronal deposits of neurofibrillary... -
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- Inhibition of expression of P-selectin by antioxidant in cholesterol-fed rats
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Lee CS, Choi JM, Park DH, Kang DY, Register T, Adams MR
- KMID: 1062190
- J Korean Med Sci.
- 1999 Feb;14(1):8-14.
- doi: 10.3346/jkms.1999.14.1.8
Butylated hydroxytoluene (BHT) can inhibit experimental atherosclerosis in animals. Although the agent is an antioxidant, the exact mechanism of the reaction in atherosclerosis is still unknown. To investigate the effects... -
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- Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells
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Wu Y, Zhang M, Liu R, Zhao C
- KMID: 2374173
- Yonsei Med J.
- 2016 Sep;57(5):1252-1259.
- doi: 10.3349/ymj.2016.57.5.1252
PURPOSE: Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances in electrolytes and the acid-base balance caused by a disorder of glucose metabolism. NHE1 is... -
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- Anti-oxidative neuroprotection by estrogens in mouse cortical cultures
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Bae YH, Hwang JY, Kim YH, Koh JY
- KMID: 1128633
- J Korean Med Sci.
- 2000 Jun;15(3):327-336.
- doi: 10.3346/jkms.2000.15.3.327
Estrogen replacement therapy in postmenopausal women may reduce the risk of Alzheimer's disease, possibly by ameliorating neuronal degeneration. In the present study, we examined the neuroprotective spectrum of estrogen against... -
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- The Protective Effects of Green Tea Extract against L-arginine Toxicity to Cultured Human Mesangial Cells
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Shin BC, Ryu HH, Chung JH, Lee BR, Kim HL
- KMID: 1778163
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S204-S209.
- doi: 10.3346/jkms.2009.24.S1.S204
The aim of this study was to investigate whether green tea extract (GTE) has the protective effects on excess L-arginine induced toxicity in human mesangial cell. Human mesangial cells treated... -
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- Glutathione recycling is attenuated by acute ethanol feeding in rat liver
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Oh SI, Kim CI, Chun HJ, Lee MS, Park SC
- KMID: 1081053
- J Korean Med Sci.
- 1997 Aug;12(4):316-321.
- doi: 10.3346/jkms.1997.12.4.316
The mechanism for ethanol-induced oxidative stress has been disputed because of the controversies on modulation of radical generating and scavenging activities by ethanol. In the present work, we attempted... -
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- Synergistic effect of peroxiredoxin II antisense on cisplatin-induced cell death
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Yoo YD, Chung YM, Park JK, Ahn CM, Kim SK, Kim HJ
- KMID: 931877
- Exp Mol Med.
- 2002 Sep;34(4):273-277.
Peroxiredoxin II (Prx II) is known not only to protect cells from oxidative damage caused by hydrogen peroxide (H2O2), but also to endow cancer cells with resistance to both... -
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- Involvement of protein kinase C pathway in UVC-stimulated phospholipase D2 activity in Vero 76 cells
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Kim S, Choi MS, Choi MU
- KMID: 1089451
- Exp Mol Med.
- 2005 Oct;37(5):418-426.
Phospholipase D (PLD) activity is known to be related to oxidant-induced cellular signaling and membrane disturbance. Previously, an induction of PLD activity in various cell lines by X-ray irradiation was... -
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- Ischemia-Modified Albumin: Could It Be a New Oxidative Stress Biomarker for Colorectal Carcinoma?
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Ellidag HY, Bulbuller , Eren E, Abusoglu S, Akgol E, Cetiner M, Yilmaz N
- KMID: 1712327
- Gut Liver.
- 2013 Nov;7(6):675-680.
BACKGROUND/AIMS: An impaired oxidative/antioxidative status plays an important role in the pathogenesis of many diseases, including cancer. The aim of this study was to evaluate the levels of the novel... -
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- Effects of aluminum on the reduction of neural stem cells, proliferating cells, and differentiating neuroblasts in the dentate gyrus of D-galactose-treated mice via increasing oxidative stress
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Nam SM, Kim JW, Yoo DY, Kim W, Jung HY, Choi JH, Hwang IK, Seong JK, Yoon YS
- KMID: 2413161
- J Vet Sci.
- 2016 Jun;17(2):127-136.
- doi: 10.4142/jvs.2016.17.2.127
Aluminum (Al) accumulation increases with aging, and long-term exposure to Al is regarded as a risk factor for Alzheimer's disease. In this study, we investigated the effects of Al and/or... -
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- Oxidative stress is associated with the number of components of metabolic syndrome: LIPGENE study
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Yubero-Serrano EM, Delgado-Lista J, Pena-Orihuela P, Perez-Martinez P, Fuentes F, Marin C, Tunez I, Jose Tinahones F, Perez-Jimenez F, Roche HM, Lopez-Miranda J
- KMID: 2154247
- Exp Mol Med.
- 2013 Jun;45(6):e28.
Previous evidence supports the important role that oxidative stress (OxS) plays in metabolic syndrome (MetS)-related manifestations. We determined the relationship between the number of MetS components and the degree of... -
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- Up-regulation of defense enzymes is responsible for low reactive oxygen species in malignant prostate cancer cells
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Lim HW, Hong S, Jin W, Lim S, Kim SJ, Kang HJ, Park EH, Ahn K, Lim CJ
- KMID: 1089461
- Exp Mol Med.
- 2005 Oct;37(5):497-506.
Reactive oxygen species (ROS) are involved in a diversity of important phenomena in the process of tumor development. To investigate the alterations of oxidative stress and their related systems in... -
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- Regulation of pro-inflammatory responses by lipoxygenases via intracellular reactive oxygen species in vitro and in vivo
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Kim SY, Kim TB, Moon KA, Kim TJ, Shin D, Cho YS, Moon HB, Lee KY
- KMID: 1094126
- Exp Mol Med.
- 2008 Aug;40(4):461-476.
- doi: 10.3858/emm.2008.40.4.461
Reactive oxygen species (ROS) performs a pivotal function as a signaling mediator in receptor-mediated signaling. However, the sources of ROS in this signaling have yet to be determined, but may... -
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- Relationship of Oxidative Stress in Hepatitis B Infection Activity with HBV DNA and Fibrosis
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Duygu F, Karsen H, Aksoy N, Taskin A
- KMID: 1245250
- Ann Lab Med.
- 2012 Mar;32(2):113-118.
- doi: 10.3343/alm.2012.32.2.113
BACKGROUND: The aim of this study was to evaluate oxidative stress in various clinical forms of hepatitis B infection and to investigate its role in the development of the chronic... -
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