- Antimicrobial Peptides in Innate Immunity against Mycobacteria
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Shin DM, Jo EK
- KMID: 2167996
- Immune Netw.
- 2011 Oct;11(5):245-252.
- doi: 10.4110/in.2011.11.5.245
Antimicrobial peptides/proteins are ancient and naturallyoccurring antibiotics in innate immune responses in a variety of organisms. Additionally, these peptides have been recognized as important signaling molecules in regulation of both... -
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- Role of hepcidin in the pathophysiology and diagnosis of anemia
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D'Angelo G
- KMID: 2270720
- Blood Res.
- 2013 Mar;48(1):10-15.
- doi: 10.5045/br.2013.48.1.10
This review summarizes the central role of hepcidin in the iron homeostasis mechanism, the molecular mechanism that can alter hepcidin expression, the relationship between hepcidin and erythropoiesis, and the pathogenetic... -
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- Anti-adenoviral Effects of Human Cationic Antimicrobial Protein-18/LL-37, an Antimicrobial Peptide, by Quantitative Polymerase Chain Reaction
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Uchio E, Inoue H, Kadonosono K
- KMID: 1798058
- Korean J Ophthalmol.
- 2013 Jun;27(3):199-203.
- doi: 10.3341/kjo.2013.27.3.199
PURPOSE: Antimicrobial peptides have an important role in self-protection of the ocular surface. Human cationic antimicrobial protein (hCAP)-18 is a linear, alpha-helical peptide that consists of a conserved pro-sequence called... -
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- Vitamin D, the Cutaneous Barrier, Antimicrobial Peptides and Allergies: Is There a Link?
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Roider E, Ruzicka T, Schauber J
- KMID: 2260330
- Allergy Asthma Immunol Res.
- 2013 May;5(3):119-128.
- doi: 10.4168/aair.2013.5.3.119
Atopic diseases such as atopic dermatitis (AD) are very common in industrialized countries. Up to 15%-30% of all children and 2%-10% of all adults suffer from AD. Already in early... -
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- Expression of Human beta-defensin mRNA in Epidermal Proliferative Diseases
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Kim YJ, Choi YK, Kim MN, Hong CK, Ro BI, Seo SJ
- KMID: 2302992
- Korean J Dermatol.
- 2003 May;41(5):551-558.
BACKGROUND: Defensins are cationic antimicrobial peptides with a wide range of antimicrobial activity against gram positive and gram negative bacteria, yeasts, fungi, and viruses. They are also believed to promote... -
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- Cathelicidin LL-37: An Antimicrobial Peptide with a Role in Inflammatory Skin Disease
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Reinholz M, Ruzicka T, Schauber J
- KMID: 2434676
- Ann Dermatol.
- 2012 May;24(2):126-135.
Chronic inflammatory skin diseases such as atopic dermatitis, psoriasis or rosacea are very common. Although their exact pathogenesis is not completely understood all three diseases are characterized by dysregulation of... -
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- Changes of Antimicrobial Peptides and Transepidermal Water Loss After Topical Application of Tacrolimus and Ceramide-dominant Emollient in Patients with Atopic Dermatitis
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Park KY, Kim DH, Jeong MS, Li K, Seo SJ
- KMID: 1713963
- J Korean Med Sci.
- 2010 May;25(5):766-771.
- doi: 10.3346/jkms.2010.25.5.766
Increased transepidermal water loss (TEWL) and downregulated antimicrobial peptides (AMPs) are observed in patients with atopic dermatitis (AD). Tacrolimus and ceramide-dominant emollients are effective in the treatment of AD by... -
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- Understanding and exploiting hepcidin as an indicator of anemia due to chronic kidney disease
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Larson DS, Coyne DW
- KMID: 2224314
- Kidney Res Clin Pract.
- 2013 Mar;32(1):11-15.
Hepcidin, produced by the liver, is the master regulator of iron balance. Serum hepcidin is increased by high iron stores, blocks intestinal iron absorption, and impairs storage iron release. Conversely,... -
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- Expression of Human Beta-Defensin in Human Male Urogenital Organs
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Chang IH, Yum SH, Myung SC, Kim YS
- KMID: 2248677
- Korean J Infect Dis.
- 2001 Aug;33(4):233-241.
BACKGROUND: Defensins are small (3.5~5 kDa) cationic antimicrobial peptides that have a broad spectrum of activity that includes gram-negative bacterias, yeasts and enveloped viruses. The defensins contain six cysteine residues... -
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- Toll-like Receptors and Antimicrobial Peptides Expressions of Psoriasis: Correlation with Serum Vitamin D Level
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Kim SK, Park S, Lee ES
- KMID: 2157857
- J Korean Med Sci.
- 2010 Oct;25(10):1506-1512.
- doi: 10.3346/jkms.2010.25.10.1506
To evaluate the association of Toll-like receptors (TLRs), antimicrobial peptides (AMPs) and vitamin D receptors (VDRs) in psoriasis, lesional (PP) and perilesional skin (PN) from psoriasis, atopic dermatitis (AD) patients... -
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- Carriage of Staphylococcus schleiferi from canine otitis externa: antimicrobial resistance profiles and virulence factors associated with skin infection
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Lee GY, Lee HH, Hwang SY, Hong J, Lyoo KS, Yang SJ
- KMID: 2454009
- J Vet Sci.
- 2019 Mar;20(2):e6.
- doi: 10.4142/jvs.2019.20.e6
The recent emergence of Staphylococcus schleiferi in dogs with otitis externa or skin and soft tissue infections has become a significant zoonotic issues. In the current study, we investigated 1)... -
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- Endovascular Treatment of Intracranial Aneurysms Using Polymer Polyglycolic-Lactic Acid Coated Coils
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Hwang SK, Kim SH
- KMID: 2134944
- Ewha Med J.
- 2012 Mar;35(1):38-43.
- doi: 10.12771/emj.2012.35.1.38
OBJECTIVES: In treatment for intracranial aneurysms by coil embolization, recanalization remains the major limitation of coiling, particularly wide-necked or larger aneurysms. The aim of this study was to evaluate technical... -
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- Serum Pro-hepcidin as an Predictor of Iron Deficiency in Anemic Patients
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Kim J, Son Y, Ihm C
- KMID: 1446274
- Lab Med Online.
- 2011 Apr;1(2):88-93.
- doi: 10.3343/lmo.2011.1.2.4
BACKGROUND: Hepcidin has recently been known as a negative regulatory hormone of iron. Hepcidin precursor, pro-hepcidin has been used as a surrogate and reported to be related to iron deficiency.... -
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- Serum Hepcidin Level as an Early Marker of Hematopoietic Activity after Allogeneic Peripheral Blood Stem Cell Transplantation
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Kim J, Kwon KC, Koo SH
- KMID: 2200509
- J Lab Med Qual Assur.
- 2013 Jun;35(1):1-7.
BACKGROUND: Hepcidin plays a central role in the regulation of iron metabolism, and hepatic iron production is stimulated by iron load and inflammation. Recent animal studies have shown that hepcidin... -
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- Relationship between Helicobacter pylori infection and iron-deficiency anemia in infants and children
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Son MH, Yeom JS, Park JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS
- KMID: 2281457
- Korean J Pediatr.
- 2009 May;52(5):544-548.
- doi: 10.3345/kjp.2009.52.5.544
PURPOSE: To elucidate a potential association between Helicobacter pylori (HP) infection and iron-deficiency anemia (IDA) in infants and children in terms of the other factors related to iron utilization and... -
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- Nitric Oxide Synthesis is Modulated by 1,25-Dihydroxyvitamin D3 and Interferon-gamma in Human Macrophages after Mycobacterial Infection
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Lee JS, Yang CS, Shin DM, Yuk JM, Son JW, Jo EK
- KMID: 1474580
- Immune Netw.
- 2009 Oct;9(5):192-202.
- doi: 10.4110/in.2009.9.5.192
BACKGROUND: Little information is available the role of Nitric Oxide (NO) in host defenses during human tuberculosis (TB) infection. We investigated the modulating factor(s) affecting NO synthase (iNOS) induction in... -
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- Serum Pro-hepcidin Could Reflect Disease Activity in Patients with Rheumatoid Arthritis
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Kim HR, Kim KW, Yoon SY, Kim SH, Lee SH
- KMID: 1778027
- J Korean Med Sci.
- 2010 Mar;25(3):348-352.
- doi: 10.3346/jkms.2010.25.3.348
The aim of this study was to analyze the relationship between serum pro-hepcidin concentration and the anemia profiles of rheumatoid arthritis (RA) and to estimate the pro-hepcidin could reflect the... -
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- Increased Expression of Cathelicidin by Direct Activation of Protease-Activated Receptor 2: Possible Implications on the Pathogenesis of Rosacea
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Kim JY, Kim YJ, Lim BJ, Sohn HJ, Shin D, Oh SH
- KMID: 2070215
- Yonsei Med J.
- 2014 Nov;55(6):1648-1655.
- doi: 10.3349/ymj.2014.55.6.1648
PURPOSE: Recent findings of increased cathelicidin protein and its proteolytic fragments in rosacea suggest a pathogenic role for cathelicidin in this disease. The relationship between cathelicidin and protease-activated receptor 2... -
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- Serum hepcidin levels and iron parameters in children with iron deficiency
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Choi HS, Song SH, Lee JH, Kim HJ, Yang HR
- KMID: 1832108
- Korean J Hematol.
- 2012 Dec;47(4):286-292.
- doi: 10.5045/kjh.2012.47.4.286
BACKGROUND: Iron deficiency (ID) and iron deficiency anemia (IDA) are common nutritional disorders in children. Hepcidin, a peptide hormone produced in the liver, is a central regulator of systemic iron... -
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- Expression and Modulation of LL-37 in Normal Human Keratinocytes, HaCaT cells, and Inflammatory Skin Diseases
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Kim JE, Kim BJ, Jeong MS, Seo SJ, Kim MN, Hong CK, Ro BI
- KMID: 1712748
- J Korean Med Sci.
- 2005 Aug;20(4):649-654.
- doi: 10.3346/jkms.2005.20.4.649
Defensins and cathelicidins (LL-37) are major antimicrobial peptides (AMPs) of the innate immune system of the human skin. In normal non-inflamed skin these peptides are negligible, but their expression can... -
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