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Nonkaryophilic T Antigen of Simian Virus 40 does not have the Functions of Transcriptional Regulation and Transformation

Kim GS, Kim YH, Kim DH

  • KMID: 1571379
  • J Bacteriol Virol.
  • 2001 Jun;31(2):155-161.
No abstract available.
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Detection of SV40 Large T Antigen in Malignant Lymphomas

Kim YA, Chang M, Paik J, Yoon SO, Jeon YK, Kim CW, Kim JE

  • KMID: 2459589
  • Korean J Pathol.
  • 2009 Aug;43(4):312-316.
BACKGROUND: The association of simian virus 40 (SV40) with certain types of human cancers, including malignant lymphomas, has been a topic of interest for some time. Although the virus is...
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Association of T Antigens with emm Genotypes of Group A Streptococci

Jung HJ, Koh EH, Kim S, Maeng KY, Kang SH

  • KMID: 2146986
  • Korean J Clin Microbiol.
  • 2006 Apr;9(1):18-23.
BACKGROUND: T typing has been used as a screening test for epidemiologic studies of group A streptococci (GAS) infections or carriers, and M typing has been performed for virulence studies....
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Distribution of T types and emm Genotypes of Streptococcus pyogenes in Jinju, 2004

Koh EH, Kim S

BACKGROUND: T antigens and emm genotypes are useful markers for epidemiologic investigation of Streptococcus pyogenes infections. Epidemiologic studies of S. pyogenes were performed on a large scale in Jinju. This...
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T Types, emm Genotypes and Antibiotic Resistance of Streptococcus pyogenes Isolated fromSchool Children in Jinju, 2006

Koh EH, Kim IS, Kim S

BACKGROUND: Streptococcus pyogenes is the most common cause of bacterial pharyngitis. T antigens and emm genotypes are essential markers for an epidemiological study of S. pyogenes. Macrolide resistance of S....
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Evaluation of Vascular Smooth Muscle Cell Lineages Derived from the Transgenic Mice Expressing Temperature-Sensitive Simian Virus 40 T Antigen Targeted to Smooth Muscle

Huh NE

BACKGROUND AND OBJECTIVES: As a part of efforts to evaluate effectiveness of aorta cell lineages derived from the transgenic mice in which expression of the temperature-sensitive SV40 large T antigen...
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Transfection of SV 40 Large T Antigen into Corneal Endothelial Cells

Cho KS, Fleming TP, Lee EH, Joo CK

  • KMID: 2205471
  • J Korean Ophthalmol Soc.
  • 1999 Mar;40(3):676-682.
The coeneal endothelium is essential for the maintenance of normal corneal hydration, thickness, and transparency. However, corneal endothelial cells are incapable of significant proliferation in vivo. As we age, the...
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Overexpression of hTERT and c-erbB-2 are correlated in ovarian epithelial cancer

Kang S, Park NH, Lee YK, Kim JW, Song YS, Kang SB, Lee HP

  • KMID: 2244587
  • Korean J Gynecol Oncol.
  • 2006 Jun;17(2):142-146.
OBJECTIVE: It is still unclear how the abnormal hTERT expression is involved in the process of ovarian carcinogenesis. A recent report demonstrated that the introduction of c-erbB-2 could efficiently induce...
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Proliferation of Corneal Endothelial Cells by Delivery of SV40 Large T Antigen

Cho KS, Song IK, Fleming TP, Joo CK

  • KMID: 2109217
  • J Korean Ophthalmol Soc.
  • 2001 Sep;42(9):1331-1335.
PURPOSE: To determine whether the delivery of the SV40 large T-antigen is a feasible method for transiently inducing proliferation of corneal endothelial cells, we delivered liposome-protein complex into bovine corneal...
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Effect of Long-term Passage on Liver-specific Functions in Immortalized Hepatocytes with a Temperature-sensitive Mutant of SV40 T Antigen

Kim BH, Seong SR, Lee WI, Dong SH, Kim HJ, Chang YW, Lee JI, Chang R

  • KMID: 2304644
  • Korean J Gastroenterol.
  • 1999 Jul;34(1):56-68.
BACKGROUND/AIMS: The transcription of liver specific genes decreases dramatically in primary hepatocyte culture. In this study, we evaluated the long-term differentiation of immortalized hepatocytes. METHODS: Immortalized rat hepatocytes were established...
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Detection of JC Virus in the Brains of Korean Glioblastoma Multiforme Patients

Han JW, Kim BH, Jeon YC, Ahn SK, Kim YS, Ahn MS

  • KMID: 1904997
  • J Korean Neurosurg Soc.
  • 2004 Sep;36(3):224-228.
OBJECTIVE: The ubiquitous human polyomavirus, JC virus(JCV) is the etiologic agent of the fatal demyelinating central nervous system(CNS) disease, progressive multifocal leukoencephalopathy(PML). Recent studies have reported the detection of the...
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Epidemiological Surveillance of Group A Streptococci Isolated from School Children Using emm Genotyping

Kim SJ

  • KMID: 2239632
  • Korean J Lab Med.
  • 2002 Dec;22(6):417-423.
BACKGROUND: Group A streptococci (GAS), the most common cause of bacterial pharyngitis, can be spread by interpersonal contact. While T typing is useful for screening, it does not completely identify...
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Immunohistochemical Study of the T-Antigen on the Transitional Cell Carcinoma of the Urinary Bladder

Kim WJ, Kim CW, Kim YK

  • KMID: 2289823
  • Korean J Urol.
  • 1988 Dec;29(6):893-902.
The T-antigen(Thomsen-Friedenreich antigen, T-Ag) has been found in malignant cells but in most normal cells, in which the T-Ag is cryptic but can be unmasked with neuraminidase. The significance of...
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Detection of JC Virus T-Ag in Early Gastric Cancer

Jang EJ, Jang JS, Kim JH, Bae HI, Suh IS

  • KMID: 2277552
  • Korean J Pathol.
  • 2010 Oct;44(5):456-461.
BACKGROUND: JC virus (JCV) is a polyomavirus that commonly infects humans and can cause progressive multifocal leukoencephalopathy in immunocompromised patients. Recently, many reports have documented detection of JCV in gastrointestinal...
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Epidemiological Characterization of Group A Streptococci Using emm Genotyping from Throat Cultures in Patients with Acute Pharyngitis in Children

Jung HJ, Lee NY, Kwon OY, Maeng KY, Kim S

PURPOSE: Group A streptococci(GAS) was isolated from the patients with acute pharyngitis. Epidemiological studies using T typing and emm genotyping was performed for GAS and compared with the results of...
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Establishment of Human Bone Marrow-Derived Mesenchymal Stem Cell Lines with SV40 Large T Antigen and Their Differentiation to Chondrocytes

Park JA, Kim EK, Koh SH, Kang HJ, Shin HY, Ahn HS

  • KMID: 2278338
  • Korean J Pediatr Hematol Oncol.
  • 2005 Apr;12(1):99-107.
PURPOSE: Mesenchymal stem cells (MSC) can be isolated from bone marrow (BM) and when systemically administrated to different species, they undergo site-specific differentiation. In this study, we isolated MSC from...
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A Experimental Model of Bladder Cancer Using Nonviral Vector Expressing Uroplakin II Promoter and SV40 T Antigen

Koh JS, Paik SY, Lee JY

  • KMID: 2293853
  • Korean J Urol.
  • 2005 Oct;46(10):1088-1093.
PURPOSE: The goal of this study was to constructing a nonviral vector, expressing the chimeric gene of the SV40 T antigen and mouse uroplakin II promoter (UPII promotor), which was...
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Establishment of Human Myofibroblast Like Cell Line Immortalized by Transfection of SV40 Largw T Gene

Kim CY, Lee HS, Jun HS, Woo GH, Yoon JH, Lee JS

  • KMID: 2084956
  • Korean J Gastroenterol.
  • 1999 Sep;34(3):345-356.
BACKGROUND/AIMS: Myofibroblast like cell (MFLC) plays an important role in hepatic fibrogenesis. A continuously proliferating human MFLC line would be valuable in studying human hepatic fibrogenesis. The present study was...
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Merkel Cell Polyomavirus Is Frequently Detected in Korean Patients with Merkel Cell Carcinoma

Chun SM, Yun SJ, Lee SC, Won YH, Lee JB

BACKGROUND: Merkel cell carcinoma (MCC) is an increasingly common neuroendocrine cancer of the skin. Merkel cell polyomavirus (MCPyV) is one of the causative agents of MCC. The prevalence of MCPyV...
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Okadaic Acid, RK682 and Calyculin Modulate TcR - Mediated Signaling Events

Lee SK, Lim JH, Cho KM, Kim HJ, Kim SW, Song YS

  • KMID: 2082998
  • Korean J Immunol.
  • 1997 Sep;19(3):327-336.
The T cell antigen receptor (TcR) in combination with costimulatory signals triggered by accessory molecules present on the surface of the antigen-presenting cells (APC) regulates the activation and growth of...
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