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Acute Dystonia by Droperidol during Intravenous Patient-Controlled Analgesia in Young Patients

Park CK, Choi HY, Oh IY, Kim MS

Patient-controlled analgesia (PCA) is an important means for postoperative analgesia with parenteral opioid. However, postoperative nausea and vomiting (PONV) remains a major problem with a PCA system. Droperidol is...
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Analgesic efficacy of oral firocoxib in ovariohysterectomized cats

Phuwapattanachart P, Thengchaisri N

The postoperative analgesic effects of firocoxib in ovariohysterectomized cats were observed. Twenty-four cats were divided into 3 groups: control (no medicine), firocoxib-1 (1 mg/kg/day) and firocoxib-3 (3 mg/kg/day). Colorado pain...
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Interaction between Intrathecal Gabapentin and Adenosine in the Formalin Test of Rats

Yoon MH, Choi JI, Park HC, Bae HB

Spinal gabapentin and adenosine have been known to display an antinociceptive effect. We evaluated the nature of the interaction between gabapentin and adenosine in formalin-induced nociception at the spinal level....
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Effect of DA-9701 on Colorectal Distension-Induced Visceral Hypersensitivity in a Rat Model

Kim ER, Min BH, Lee TH, Son M, Rhee PL

  • KMID: 1792361
  • Gut Liver.
  • 2014 Jul;8(4):388-393.
BACKGROUND/AIMS: DA-9701 is a newly developed drug made from the vegetal extracts of Pharbitidis semen and Corydalis tuber. The aim of this study was to evaluate the effect of DA-9701...
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Effects of Co-Administration of Intrathecal Nociceptin/Orphanin FQ and Opioid Antagonists on Formalin-Induced Pain in Rats

Lee H

PURPOSE: Nociceptin/orphanin FQ (N/OFQ) as an endogeneous hexadecapeptide is known to exert antinociceptive effects spinally. The aims of this study were to demonstrate the antinociceptive effects of i.t. N/OFQ and...
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Spinal Gabapentin and Antinociception: Mechanisms of Action

Yoon MH, Choi JI, Jeong SW

Spinal gabapentin has been known to show the antinociceptive effect. Although several assumptions have been suggested, mechanisms of action of gabapentin have not been clearly established. The present study was...
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Protective Effects of Gabapentin on Allodynia and alpha2delta1-Subunit of Voltage-dependent Calcium Channel in Spinal Nerve-Ligated Rats

Hahm TS, Ahn HJ, Bae CD, Kim HS, Lim SW, Cho HS, Lee SM, Sim WS, Kim JA, Gwak MS, Choi SJ

This study was designed to determine whether early gabapentin treatment has a protective analgesic effect on neuropathic pain and compared its effect to the late treatment in a rat neuropathic...
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The Effect of Intrathecal Gabapentin on Mechanical and Thermal Hyperalgesia in Neuropathic Rats Induced by Spinal Nerve Ligation

Cho HS, Kim MH, Choi DH, Lee JI, Gwak MS, Hahm TS

Gabapentin decreases the level of glutamate and elevates that of garmma-amino-butyric acid in the central nervous system. Gabapentin was shown to have antinociceptive effects in several facilitated pain models. Intrathecal...
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Ethanol Sclerotherapy for the Management of Craniofacial Venous Malformations: the Interim Results

Lee IH, Kim KH, Jeon P, Byun HS, Kim HJ, Kim ST, Kim YW, Kim DI, Choi JY

OBJECTIVE: We wanted to evaluate the safety and feasibility of ethanol sclerotherapy for treating craniofacial venous malformations (CVMs). MATERIALS AND METHODS: From May 1998 to April 2007, 87 patients (40...
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