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Development of a New Approach to Determine the Potency of Bacille Calmette–Guérin Vaccines Using Flow Cytometry

Gweon E, Choi C, Kim J, Kim B, Kang H, Park T, Ban S, Bae M, Park S, Jeong J

OBJECTIVES: To circumvent the limitations of the current golden standard method, colony-forming unit (CFU) assay, for viability of Bacille Calmette–Guérin (BCG) vaccines, we developed a new method to rapidly and...
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Pretreatmet with 5% lidocaine patch reduces cannula-induced and propofol-induced pain: a randomized, double-blind, placebo-controlled study

Hong JM, Lee HJ, Cho AR, Baik JS, Lee DW, Ji YT, Yoo KC, Kim HK

BACKGROUND: The purpose of this study was to determine the efficacy of 5% lidocaine patch in reducing propofol-induced pain and cannula-induced pain. METHODS: In a randomized, double-blind study, 126 patients were...
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Drug utilization review of mupirocin ointment in a Korean university-affiliated hospital

Youn SH, Lee SS, Kim S, Lee JA, Kim BJ, Kim J, Han HK, Kim JS

BACKGROUND/AIMS: Intranasal mupirocin and chlorhexidine bathing are candidate strategies to prevent healthcare-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). In Korea, intranasal mupirocin is not available, and mupirocin ointment, an...
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The efficacy of low-dose transdermal fentanyl in opioid-naive cancer patients with moderate-to-severe pain

Kang JH, Oh SY, Song SY, Lee HY, Kim JH, Lee KE, Lee HR, Hwang IG, Park SH, Kim WS, Park YS, Park K

BACKGROUND/AIMS: Little is known about the efficacy of low-dose transdermal fentanyl (TDF) patches in opioid-naive patients with moderate-to-severe cancer pain. METHODS: This study had an open-label, prospective design, and was conducted...
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A Case of Fentanyl Toxicity with Misused Durogesic Transdermal Patch

Yun SH, Jung HM, Kim JH, Han SB, Kim JS, Paik JH

  • KMID: 1482720
  • J Korean Soc Clin Toxicol.
  • 2013 Jun;11(1):49-52.
Fentanyl, a synthetic, highly selective opioid micro-receptor agonist, is 50 to 100 times more potent than morphine. The low molecular weight, high potency, great transdermal permeation rate and lipid solubility...
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Contact dermatitis caused by ambulatory blood pressure monitoring

Park BW, Chung JW, Hyon MS, Han DC

No abstract available.
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Multiple Trichoepithelioma Improved by Intralesional Bleomycin Injection

Son HH, Jung SW, Sim HS, Lee SK

  • KMID: 2247312
  • Korean J Dermatol.
  • 2012 Sep;50(9):814-817.
Multiple trichoepithelioma is a benign adnexal neoplasm characterized by the presence of many small papules that appear predominantly on the face. Clinical improvement have been demonstrated after several treatments such...
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Characterization of Bladder Selectivity of Antimuscarinic Agents on the Basis of In Vivo Drug-Receptor Binding

Yamada S, Kuraoka S, Osano A, Ito Y

  • KMID: 2232961
  • Int Neurourol J.
  • 2012 Sep;16(3):107-115.
The in vivo muscarinic receptor binding of antimuscarinic agents (oxybutynin, solifenacin, tolterodine, and imidafenacin) used to treat urinary dysfunction in patients with overactive bladder is reviewed. Transdermal administration of oxybutynin...
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Transdermal Fentanyl for Chronic Low Back Pain

Ohtori S, Inoue G, Orita S, Eguchi Y, Ochiai N, Kishida S, Takaso M, Aoki Y, Kuniyoshi , Nakamura J, Ishikawa T, Arai G, Miyagi M, Kamoda H, Suzuki M, Toyone T, Takahashi

PURPOSE: Chronic low back pain is a common clinical problem. As medication, non-steroidal anti-inflammatory drugs are generally used; however, they are sometimes non-effective. Recently, opioids have been used for the...
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Acute Dermal Toxicity Study of Bee Venom (Apis mellifera L.) in Rats

Han SM, Lee GG, Park KK

  • KMID: 1432245
  • Toxicol Res.
  • 2012 Jun;28(2):99-102.
Bee venom (Apis mellifera L. BV) has been used as a cosmetic ingredient for anti-ageing, anti-inflammatory and antibacterial functions. The aim of this study was to evaluate the acute toxicity...
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Topical Steroids to Treat Granulomatous Mastitis: A Case Report

Altintoprak F

Idiopathic granulomatous mastitis (IGM) is a rare and chronic benign disease of the breast. Histologically, the disease presents as an intense inflammatory reaction with non-caseated granulomas that are the characteristic...
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High-Dose Fentanyl Patch for Cancer Pain of a Patient with Cholangiocarcinoma

Kim JH, Kim M, Sung CW, Kim HS, Jang HJ, Shin YC, Jung JY

We describe here a patient who obtained a good analgesic effect with high-dose fentanyl patches for controlling cancer pain. A 52-year-old man was referred to our hospital because of severe...
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Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application

Raina R, Verma PK, Pankaj NK, Prawez S

Present study was undertaken to study the effect of cypermethrin on oxidative stress after chronic dermal application. The insecticide was applied dermally at 50 mg/kg body weight in different groups...
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Sociodemographic and Smoking Behavioral Predictors Associated with Smoking Cessation According to Follow-up Periods: A Randomized, Double-blind, Placebo-controlled Trial of Transdermal Nicotine Patches

Myung SK, Seo HG, Park S, Kim Y, Kim DJ, Lee DH, Seong MW, Nam MH, Oh SW, Kim JA, Kim MY

This study investigated sociodemographic and smoking behavioral factors associated with smoking cessation according to follow-up periods. In this randomized, double-blind, placebo-controlled trial of transdermal nicotine patches, subjects were a total...
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Polysaccharides isolated from Phellinus gilvus enhances dermal wound healing in streptozotocin-induced diabetic rats

Bae JS, Jang KH, Jin HK

  • KMID: 1114859
  • J Vet Sci.
  • 2005 Jun;6(2):161-164.
Dermal wound healing is a complex process that involved inflammation leading to re-epithelialization, granulation tissue, and tissue remodeling. Previous studies from our laboratory have shown that polysaccharides isolated from fungus,...
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Initial Dose Cascade of TTS Fentanyl with Proper Adjuvant Medications in Cancer Pain

Baik SW, Kim KH, Kim YC, Lee SC, Kim DK, Jung JE

According to the three step-ladder analgesics in patients with cancer pain, adjuvant drugs are required for pain relief according to the pain character and also to reduce side effects of...
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Evaluation of efficacy and safety of fentanyl-TTS in adult patients with cancer-related pain

Kim HK, Lee KS, Hong YS, Lee BK, Song CW, Park JN, Cho SK, Kim JY

  • KMID: 2251353
  • Korean J Med.
  • 1999 Sep;57(3):348-356.
The transdermal administration of narcotics is one of the alternative ways of providing adequate pain relief for the patients with chronic cancer pain. A Phase 4 trial was conducted to evaluate the...
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Long-term Impacts of 1alpha-Hydroxy Vitamin D3 on The Bone Mineral Density and Bone Metabolism during Percutaneous Estrogen Replacement Therapy in Postmenopausal Women

Kim SW, Park ED, Kim DH, Kim HY, Suk WI, Seo NW, Lee SM, Noh SH

  • KMID: 2260905
  • Korean J Obstet Gynecol.
  • 1998 Apr;41(4):968-977.
To evaluate the impacts of vitamin-D on the bone mineral density and bone metabolism in the estrogen replacement 1-year trials of 3 grops: Group 1 was 35 wemen recieved the...
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The Postoperative Analgesic Effect of Transdermal Fentanyl with Patch in Total Abdominal Hysterectomy

Kim HM, Kim JK, Hyun HS, Song HC

BACKGROUND: Compared with conventional routes of delivering potent analgesics to postoperative patients, transdermal administration of fentanyl offers the advantages of simplicity and noninvasiveness. The analgesic efficacy and safty of transdermal...
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Clinical Features and provocation tests of vitamin K1 dermatitis

Kim K, Chae YS, Suh KS, Kim ST

  • KMID: 1693646
  • Korean J Dermatol.
  • 1993 Jun;31(3):305-311.
BACKGROUND: Two types of local reactions due to cutaneous administration of vitamin K. eczematoid, and indurated pilaque and localized scleroderma, have been described. In the acute phase, a generalized maculopapular...
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