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Acetaminophen in Pediatrics

No authors listed

  • KMID: 2103962
  • J Korean Pediatr Soc.
  • 1978 Nov;21(11):834.
No abstract available.
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A Case of Acetaminophen-induced Acute Interstitial Nephritis Presenting with Acute Renal Failure

Jeon HS, Ha TS

  • KMID: 2098854
  • J Korean Soc Pediatr Nephrol.
  • 2006 Oct;10(2):228-232.
Acute interstital nephritis can occur by acetaminophen, but it is rarely presented as acute renal failure with azotemia. We report a case of acute interstitial nephritis induced by acetaminophen in...
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A case of acetaminophen induced bronchial asthma without aspirin sensitivity

Kim SS, Lee SK, Nahm DH, Park HS

  • KMID: 2285986
  • J Asthma Allergy Clin Immunol.
  • 2000 Jun;20(3):545-550.
Acetaminophen is a widely used analgesic-antipyretic. Hypersensitivity reactions to acetaminophen are rare and selective sensitivity to acetaminophen without aspirin or non-steroidal antiinflammatory drug intolerance is even rarer. We experienced a...
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A Case of Acute Renal Failure Induced by Acetaminophen Intoxication

Lee JY, Gil HW, Yang JO, Lee EY, Hong SY

  • KMID: 2259005
  • Korean J Med.
  • 2011 Mar;80(3):348-351.
Acetaminophen is a widely used analgesic and antipyretic. Acetaminophen-induced kidney injury is poorly described. Hepatorenal syndrome, prerenal failure, and direct toxicity of acetaminophen metabolites could be involved in the development...
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A Case of Fixed Drug Eruption Due to Acetaminophen

Min EJ, Lim DH, Kim JH, Choi SW, Son BK

  • KMID: 2207508
  • J Korean Pediatr Soc.
  • 2000 Aug;43(8):1149-1152.
Fixed drug eruption normally presents as single or multiple sharply demarcated erythematous lesions that recur at the same location upon re-exposure to the offending agent. When the acute inflammation subsides, it often...
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The Clinical Use of the Plasma Acetaminophen Halflife in NAC-treated Acetaminophen Overdose

Lee SH, Lee MJ, Lee WJ, Lee WJ, Kim SK

  • KMID: 2100685
  • J Korean Soc Emerg Med.
  • 2003 Mar;14(1):56-60.
PURPOSE: A plasma acetaminophen halflife of more than 4 hours has been correlated with hepatotoxicity in acetaminophen overdosing not treated with an antidote. However, the acetaminophen halflife has not been...
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Drug reaction with eosinophilia and systemic symptom induced in a 9-year-old boy

Song HS, Choi WH, Choi WB, Yang S, Hwang IT, Baek HS

The drug reaction with eosinophilia and systemic symptom (DRESS) is a severe adverse drug-induced reaction. Acetaminophen is extensively used as an over-the-counter drug as well as a medical therapeutic. In...
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Ethanol prevents from acetaminophen inducible hepatic necrosis by inhibiting its metabolic activation in mice

Lee SM, Cho TS, Cha YN

  • KMID: 1562330
  • Korean J Physiol Pharmacol.
  • 1998 Apr;2(2):261-269.
Concomitant administration of a single acute dose of ethanol (4 g/kg) protected mice from the hepatocellular injury observed upon administration of a large dose of acetaminophen (400 mg/kg). This was evidenced by the...
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A Case of Acute Hepatic Failure due to Acetaminophen Overdose Treated with Molecular Adsorbents Recirculating System(R)

Yang BK, You JS, Joo YS, Chung SP, Lee HS

  • KMID: 2025762
  • J Korean Soc Clin Toxicol.
  • 2014 Jun;12(1):31-34.
We report on a patient who developed acute hepatic failure despite intravenous N-acetyl cysteine therapy who was treated with the Molecular Adsorbents Recirculating System (MARS). She presented 20 hours after the...
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Acute Generalized Exanthematous Pustulosis in a 2-Year-Old Female

Lee SH, Lee JW, Lee WS

  • KMID: 2250271
  • Korean J Dermatol.
  • 2003 Jan;41(1):96-99.
Acute generalized exanthematous pustulosis(AGEP) presents with an abrupt onset of widespread pustules on erythematous base and rapid spontaneous healing. AGEP may be caused by a variety of causative factors such...
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Is it Adequate to Determine Acetaminophen Toxicity Solely on Patients' History? An Analysis on Clinical Manifestation of Intoxication Patients with Positive Serum Acetaminophen Concentrations

Kim JH, Jeong WJ, Ryu S, Cho YC, Moon JH, Choi HS, Yang SH, Chung HS

PURPOSE: Acute acetaminophen intoxication is a common occurrence that can cause lethal complications. In most domestic emergency departments, clinicians tend to treat acetaminophen intoxication based on patients' history alone, simply...
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Evaluation of Fever Reducing Methods in Children

Lim SY, Lee HJ, Mok SH, Kwon HJ, Lee IS

  • KMID: 2142444
  • J Korean Pediatr Soc.
  • 1994 Jun;37(6):746-751.
The efficacy of acetaminophen, sponging plus acetaminophen, and sponging alone as method of lowering body temperature was compared in 108 children aged 8 weeks to 5 years who presented with...
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Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis Associated with Acetaminophen Use during Viral Infections

Ban GY, Ahn SJ, Yoo HS, Park HS, Ye YM

An association between drug treatment for viral infections and severe cutaneous adverse reactions has been noted. We investigated six patients diagnosed with Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)...
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A case of acetaminophen induced anaphylaxis without aspirin sensitivity

Kim YJ, Ryu KH, Yu M, Oh HJ, Park CH, Maeng SH, Cho YJ

  • KMID: 2252784
  • Korean J Med.
  • 2003 Nov;65(Suppl 3):S926-S930.
Acetaminophen is a world-wide used analgesic and anti-pyretic drug with less anti-in-flammatory effect, available without prescription in most countries. Allergic-like reactions to this drug, including urticaria, angioedema, and anaphylactic reactions...
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Acetaminophen Induced Cytotoxicity and Altered Gene Expression in Cultured Cardiomyocytes of H9C2 Cells

Jin SM, Park K

  • KMID: 2380178
  • Environ Health Toxicol.
  • 2012 ;27(1):e2012011.
OBJECTIVES: Hepatotoxicity of acetaminophen has been widely studied. However, the adverse effects on the heart have not been sufficiently evaluated. This study was performed to investigate cytotoxicity and alterations of...
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A Case of Fixed Drug Eruption Caused by Acetaminophen in a Child

Hong KB, Jin YM, Kang J, Im IJ, Roh EJ, Son JS, Chung EH

  • KMID: 2314522
  • Pediatr Allergy Respir Dis.
  • 2007 Sep;17(3):314-319.
Fixed drug eruption (FDE) is an eruption, which recurs at the same site or sites on each administration of the causative drug, and heals with residual hyperpigmentation. FDE is caused...
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A Case Rhabdomyolysis by Rare Causes: After Consumption of Common Doses of Acetaminophen and Sauna

Kim HJ, Lee IS, Whang YH, Bae YM, Seo GD, Kim MJ, Kim SH, Kim ID

  • KMID: 2254605
  • Korean J Nephrol.
  • 2000 Jan;19(1):153-157.
A 21-year-young man had an episode of myalgia and chilling 3 days prior to hospital admission. He had consumed common doses of acetaminophen for one day, and was presented in...
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Effect of 4-Methylpyrazole for Acetaminophen Hepatotoxicity in a Rat Model

Lee WJ, Oh DR, Park SH, Park KN, Rue EY, Kim SK, Lee MJ

  • KMID: 1998912
  • J Korean Soc Emerg Med.
  • 1999 Mar;10(1):19-26.
BACKGROUND: Hepatic necrosis after acetaminophen overdose results from the increased formation of a highly toxic intermediatc(N-acetyl-p-benzoquinoneimine), produced by acetaminophen metabolism through the cytochrome P450 mixed function oxidase system. N-acetyl-p-benzoquinoneimine is...
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Acetaminophen-Induced Hepatotoxicity in Cultured NCTC-1469 Cell Line

Lee KE

Acetaminophen is a mild analgesic and antipyretic agent that is safe and effective when taken in therapeutic doses. Ingestion of overdoses, however, may lead to acute liver failure accompanied by...
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Rapid onset of Stevens-Johnson syndrome and toxic epidermal necrolysis after ingestion of acetaminophen

Kim EJ, Lim H, Park SY, Kim S, Yoon SY, Bae YJ, Kwon HS, Cho YS, Moon HB, Kim TB

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, but life-threatening, severe cutaneous adverse reactions most frequently caused by exposure to drugs. Several reports have associated the use of...
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