Korean J Med.
2011 Mar;80(3):348-351.
A Case of Acute Renal Failure Induced by Acetaminophen Intoxication
- Affiliations
-
- 1Department of Internal Medicine, Soonchunhyang University College of Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea. hwgil@schmc.ac.kr
Abstract
- Acetaminophen is a widely used analgesic and antipyretic. Acetaminophen-induced kidney injury is poorly described. Hepatorenal syndrome, prerenal failure, and direct toxicity of acetaminophen metabolites could be involved in the development of acute renal failure with acetaminophen intoxication. We treated a 58-year-old female who was found stuporous and brought to the emergency room by ambulance. She had ingested acetaminophen 4~5 g per day for a chronic headache for over 10 years. At presentation, she had ingested about 8 g of acetaminophen. She presented in non-oliguric acute renal failure with hepatic injury. Hemoperfusion, hemodialysis, and N-acetylcysteine infusion were applied. The creatinine peaked on the sixth day. Subsequently, her renal function recovered. After 34 days, she was discharged in relatively good condition. In conclusion, supportive care and proper extracorporeal therapy can improve the survival in acute renal failure after acetaminophen intoxication.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of Acetaminophen-induced Acute Interstitial Nephritis Presenting with Acute Renal Failure
- A Case Rhabdomyolysis by Rare Causes: After Consumption of Common Doses of Acetaminophen and Sauna
- A Case of Acute Hepatic Failure due to Acetaminophen Overdose Treated with Molecular Adsorbents Recirculating System(R)
- Acetaminophen-Induced Acute Liver Failure
- Is it Adequate to Determine Acetaminophen Toxicity Solely on Patients' History? An Analysis on Clinical Manifestation of Intoxication Patients with Positive Serum Acetaminophen Concentrations
