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Effect Modification of Acetaldehyde Dehydrogenase 2 rs671 Polymorphism on the Association between Alcohol Intake and Blood Pressure: the Dong-gu Study

Kim HY, Choi CK, Kweon SS, Lee YH, Nam HS, Park KS, Ryu SY, Choi SW, Shin MH

BACKGROUND: Elevated blood pressure is a major preventable cause of cardiovascular diseases. Alcohol consumption is a well-known risk factor of elevated blood pressure. The aldehyde dehydrogenase 2 (ALDH2) polymorphism is...
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Epileptic Seizure Due to Disulfiram Treatment

Erensoy H, Sargin AE

Disulfiram has been used for the treatment of alcohol dependence for nearly 65 years and is approved by the Food and Drug Administration. It causes negative reinforcement by accumulating toxic...
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Alcohol consumption and gastric cancer risk in Korea: a case-control study

Kim MH, Kim SA, Park CH, Eun CS, Han DS, Kim YS, Song KS, Choi BY, Kim HJ

BACKGROUND/OBJECTIVES: The International Agency for Research on Cancer defined alcohol beverages and acetaldehyde derived from alcoholic beverages as a Group 1 carcinogen to humans. However, the association between alcohol consumption...
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Effects of DA-5513 on alcohol metabolism and alcoholic fatty liver in rats

Yu JY, Nguyen HT, Yong CS, Park HG, Jun JH, Kim JO

Hangover is characterized by a number of unpleasant physical and mental symptoms that occur after heavy alcohol drinking. In addition, consistently excessive alcohol intake is considered as a major reason...
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Pilot Study of a Brief WeChat Intervention in China to Increase Students' Willingness to Assist a Flushing Student to Reduce Alcohol Use

Zhang F, Yuen LW, Ding L, Newman IM, Shell DF

OBJECTIVES: This pilot study tested the effectiveness of a brief alcohol-related intervention delivered by the social media app WeChat to teach about ethanol-induced facial flushing and increase the willingness of...
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Hangover relieving effect of Sanghwang mushroom mycelium cultured in germinated buckwheat

An YJ, Cho SM, Kim MS, Moon HH, Park DS, Jeon NG, Lee Y, Han CH

The present study was performed to evaluate the hangover relieving effect of germinated buckwheat (GB) and Sanghwang mushroom mycelium cultured in GB (SGB). Both GB and SGB showed 1,1-diphenyl-2-picrylhydrazyl radical...
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Associations of alcohol consumption and alcohol flush reaction with leukocyte telomere length in Korean adults

Wang H, Kim H, Baik I

BACKGROUND/OBJECTIVES: Telomere length is a useful biomarker for determining general aging status. Some studies have reported an association between alcohol consumption and telomere length in a general population; however, it...
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Study of the removal difference in indoor particulate matter and volatile organic compounds through the application of plants

Hong SH, Hong J, Yu J, Lim Y

This study was conducted to evaluate the ability of plants to purify indoor air by observing the effective reduction rate among pollutant types of particulate matter (PM) and volatile organic...
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Effect of the Mixture of Pueraria lobata and Sorbus commixta Extract on the Alcohol-induced Hangover in Rats

Hong SC, Yoo JH, Oh MH, Lee H, Park YS, Parthasarathi S, Park JD, Pyo MK

Pueraiae Radix (PR), Pueratia Folium (PF) and Sorbus commixta (SC) mixture, namely GS-SP (PR (1)/PF (2)/SC (0.5): v/v/v) was developed as hangover-relieving elixir and its effects on alcoholic metabolism have...
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Alcohol and brain health: from mechanisms to interventions

Min JA, Kim DJ, Lee CU

Alcohol-related problems are prevalent and lead to substantial economic, physical, and psychological burden. Among the various effects of alcohol, the effect on the brain is a matter of importance. The...
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Alcohol-Related Neurologic Disorders: Ten Years of Experiences

Oh SH, Kim SY, Park KS, Park SH

  • KMID: 2185022
  • J Korean Neurol Assoc.
  • 2009 May;27(2):85-97.
Alcohol-related disorders are among the most costly health problems worldwide. Ingested alcohol is mainly metabolized by an oxidative pathway in the liver. Alcohol and its metabolic products (e.g., acetaldehyde and...
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The Effects of Ethanol and Acetaldehyde on Corpus Cavernosal Smooth Muscle of the Rabbit

Lee KR, Bae JH, Kim JW, Shim KS, Oh MM, Park MG, Moon DG, Kim JJ

  • KMID: 2298727
  • Korean J Androl.
  • 2009 Dec;27(3):170-176.
PURPOSE: This study is to assess the pharmacologic effects of ethanol and its metabolite, acetaldehyde on potassium channels of the corpus cavernosal smooth muscle of the rabbit. MATERIALS AND METHODS: Cavernosal...
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Salsolinol in the Pathophysiology of Alcohol Dependence and Parkinson's Disease

Chung IW, Jeong SH, Kim JY

  • KMID: 2341438
  • J Korean Neuropsychiatr Assoc.
  • 2008 May;47(3):217-224.
Salsolinol, a dopamine-derived tetrahydroisoquinoline, is one of the endogenous alkaloids structurally related to morphine. It has been implicated in the pathophysiology of alcohol dependence and Parkinson's disease since it's first...
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In vitro inhibition of 10-formyltetrahydrofolate dehydrogenase activity by acetaldehyde

Mun JA, Doh E, Min H

Alcoholism has been associated with folate deficiency in humans and laboratory animals. Previous study showed that ethanol feeding reduces the dehydrogenase and hydrolase activity of 10-formyltetrahydrofolate dehydrogenase (FDH) in rat...
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Alcohol Abuse Related Medical Problems and Treatment: Focus on Alcoholic Liver Disease

Paik YH

  • KMID: 2341039
  • J Korean Neuropsychiatr Assoc.
  • 2004 Nov;43(6):638-645.
Alcohol abuse is related to diverse medical problems including neuropsychiatric problems, malignant neoplasms, cardiovascular diseases and liver diseases. The liver is the organ most severely affected by alcoholism. Alcoholic liver...
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Hypotension Caused by a Disulfiram-Alcohol Reaction

Lee SL, Ryu SY, Kim HY

  • KMID: 2194052
  • J Korean Soc Emerg Med.
  • 2002 Dec;13(4):575-577.
Disulfiram, or antabuse, is used in the treatment of chronic alcoholism since it causes an unpleasant aversive reaction to alcohol. It works by inactivating hepatic aldehyde dehydrogenase, leading to a...
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Metabolism of Alcohol and Its Clinical Role

Yang JM

  • KMID: 1890014
  • Korean J Hepatol.
  • 2001 Sep;7(3):345-348.
No abstract available
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Two cases of alcohol-induced asthma

Sohn SW, Chang YS, Lee JY, Jung JW, Kim SH, Kim YK, Cho SH, Min KU, Kim YY

  • KMID: 2285925
  • J Asthma Allergy Clin Immunol.
  • 2001 Dec;21(6):1201-1205.
Alcohol-induced asthma is defined as exacerbation of asthmatic symptoms after drinking alcoholic beverages. This phenomenon is rare in Caucasians and is more specific to Asians. It has been observed among...
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Effects of acetaldehyde on responses of rabbit corpus cavernosal smooth muscle

Kim HJ, Sohng I, Lee G, Kim JJ, Koh SK

Ethanol has various effects on male sexual activity under the influence of direct and indirect, in acute and chronic alcohol ingestion. However, whether acetaldehyde, a principal metabolite of ethanol, may...
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The Effects of Anticholinesterase Drugs on Gastric Motility

Choi HC, Kim JH, Ha JH, Lee KY, Kim WJ, Kwak DS, Kim SH, Song PH, Yeo JH

  • KMID: 2320289
  • Yeungnam Univ J Med.
  • 1999 Dec;16(2):318-325.
BACKGROUND: Anticholinesterase drug inhibits acetylcholinesterase(AChE), induce accumulation of acetylcholine(ACh) near cholinergic receptors and cholinergic stimulation. This experiment was performed to study the effects of anticholinesterase drugs on gastric motility and...
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