- Letter to the Editor: 17Beta-estradiol Stimulates Glucose Uptake Through Estrogen Receptor and AMP-activated Protein Kinase Activation in C2C12 Myotubes (Korean J Obes 2016;25:190-6)
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Kwak HB
- KMID: 2376824
- J Obes Metab Syndr.
- 2017 Mar;26(1):76-77.
- doi: 10.7570/jomes.2017.26.1.76
No abstract available. -
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- AMPK and Type 2 Diabetes Mellitus
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Son HS
- KMID: 2008286
- J Korean Diabetes Assoc.
- 2002 Dec;26(6):443-450.
No abstract available. -
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- The Role of AMPK in Vascular Endothelium
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Lee WJ, Kim JY, Koh EH, Han SM, Kim MS, Lee KU, Park JY
- KMID: 2177798
- J Korean Diabetes Assoc.
- 2005 Jan;29(1):1-5.
No abstract available. -
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- Regulation of exercise-stimulated glucose uptake in skeletal muscle
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Koh HJ
- KMID: 2328142
- Ann Pediatr Endocrinol Metab.
- 2016 Jun;21(2):61-65.
- doi: 10.6065/apem.2016.21.2.61
AMP-activated protein kinase (AMPK) is a Ser/Thr kinase that has been thought to be an important mediator for exercise-stimulated glucose uptake in skeletal muscle. Liver kinase B1 (LKB1) is an... -
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- Regulation and function of AMPK in physiology and diseases
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Jeon SM
- KMID: 2361532
- Exp Mol Med.
- 2016 Jul;48(7):e245.
- doi: 10.1038/emm.2016.81
5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an evolutionarily conserved serine/threonine kinase that was originally identified as the key player in maintaining cellular energy homeostasis. Intensive research over the last... -
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- Response: 17Beta-estradiol Stimulates Glucose Uptake Through Estrogen Receptor and AMP-activated Protein Kinase Activation in C2C12 Myotubes (Korean J Obes 2016;25:190-6)
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Lee KH, Jo KJ, Kim JY, Baik HW, Lee SK
- KMID: 2376825
- J Obes Metab Syndr.
- 2017 Mar;26(1):78-79.
- doi: 10.7570/jomes.2017.26.1.78
No abstract available. -
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- ¹H-NMR Analysis of Metabolic Changes Induced by Snf1/AMP-Activated Protein Kinase During Environmental Stress Responses
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Kim J, Oh J, Yoon DH, Sung GH
- KMID: 2470147
- Mycobiology.
- 2019 Sep;47(3):346-349.
- doi: 10.1080/12298093.2019.1625854
AMP-activated protein kinase sucrose non-fermenting 1 (Snf1) is a representative regulator of energy status that maintains cellular energy homeostasis. In addition, Snf1 is involved in the mediation of environmental stress... -
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- Effects of AMP-activated Protein Kinase Activating Compounds and Its Mechanism
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Choi HC
- KMID: 2049802
- Yeungnam Univ J Med.
- 2012 Dec;29(2):77-82.
- doi: 10.12701/yujm.2012.29.2.77
AMP-activated protein kinase (AMPK) is an important cellular fuel sensor. Its activation requires phosphorylation at Thr-172, which resides in the activation loop of the alpha1 and alpha2 subunits. Several AMPK... -
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- Controls of Nuclear Factor-Kappa B Signaling Activity by 5’-AMP-Activated Protein Kinase Activation With Examples in Human Bladder Cancer Cells
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Choi BH, Lee DH, Kim J, Kang JH, Park CS
- KMID: 2365710
- Int Neurourol J.
- 2016 Sep;20(3):182-187.
- doi: 10.5213/inj.1632718.359
Generally, both lipopolysaccharide (LPS)- and hypoxia-induced nuclear factor kappa B (NF-κB) effects are alleviated through differential posttranslational modification of NF-κB phosphorylation after pretreatment with 5'-AMP-activated protein kinase (AMPK) activators such... -
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- Sirt1 as a New Therapeutic Target in Metabolic and Age-Related Diseases
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Lee DH
- KMID: 1730001
- Chonnam Med J.
- 2010 Aug;46(2):67-73.
- doi: 10.4068/cmj.2010.46.2.67
Sirt1 among the mammalian sirtuins has generated intense scientific interest in recent years, mainly because of its effects on longevity, metabolism, and other aging-related processes. Via nicotinamide adenine dinucleotide (NAD)-dependent... -
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- AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain
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Ramamurthy S, Ronnett G
- KMID: 1438549
- Exp Neurobiol.
- 2012 Jun;21(2):52-60.
- doi: 10.5607/en.2012.21.2.52
5'-adenosine monophosphate-activated protein kinase (AMPK) is an evolutionarily conserved cellular and organismal energy integrator that responds to numerous stimuli with the overall intention to facilitate energy conservation and enhance energy... -
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- Reserpine treatment activates AMP activated protein kinase (AMPK)
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Park R, Lee KI, Kim H, Jang M, Ha TK, Oh WK, Park J
- KMID: 2393795
- Nat Prod Sci.
- 2017 Sep;23(3):157-161.
- doi: 10.20307/nps.2017.23.3.157
Reserpine is a well-known medicine for the treatment of hypertension, however the role of reserpine in cell signaling is not fully understood. Here, we report that reserpine treatment induces the... -
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- Humanin suppresses receptor activator of nuclear factor-κB ligand-induced osteoclast differentiation via AMP-activated protein kinase activation
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Kang N, Kim KW, Shin DM
- KMID: 2455817
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):411-417.
- doi: 10.4196/kjpp.2019.23.5.411
Humanin (HN) is a mitochondrial peptide that exhibits cytoprotective actions against various stresses and diseases. HN has been shown to induce the phosphorylation of AMP-activated protein kinase (AMPK), which is... -
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- 5-aminoimidazole-4-carboxamide Riboside Induces Apoptosis Through AMP-activated Protein Kinase-independent and NADPH Oxidase-dependent Pathways
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Wi SM, Lee KY
- KMID: 2391720
- Immune Netw.
- 2014 Oct;14(5):241-248.
- doi: 10.4110/in.2014.14.5.241
It is debatable whether AMP-activated protein kinase (AMPK) activation is involved in anti-apoptotic or pro-apoptotic signaling. AICAR treatment increases AMPK-alpha1 phosphorylation, decreases intracellular reactive oxygen species (ROS) levels, and significantly... -
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- Lonchocarpine Increases Nrf2/ARE-Mediated Antioxidant Enzyme Expression by Modulating AMPK and MAPK Signaling in Brain Astrocytes
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Jeong YH, Park JS, Kim DH, Kim HS
- KMID: 2374611
- Biomol Ther.
- 2016 Nov;24(6):581-588.
- doi: 10.4062/biomolther.2016.141
Lonchocarpine is a phenylpropanoid compound isolated from Abrus precatorius that has anti-bacterial, anti-inflammatory, antiproliferative, and antiepileptic activities. In the present study, we investigated the antioxidant effects of lonchocarpine in brain... -
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- AMP-activated protein kinase Activating Agent and Its Implication
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Choi HC
- KMID: 1497647
- Endocrinol Metab.
- 2012 Jun;27(2):109-115.
- doi: 10.3803/EnM.2012.27.2.109
AMP-activated protein kinase (AMPK) is an important cellular fuel sensor. Activation of AMPK requires phosphorylation at threonine (Thr)-172, which resides in the activation loop of the alpha1 and alpha2 subunits.... -
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- Anti-proliferative Effect of 15,16-Dihydrotanshinone I Through Cell Cycle Arrest and the Regulation of AMP-activated Protein Kinase/Akt/mTOR and Mitogen-activated Protein Kinase Signaling Pathway in Human Hepatocellular Carcinoma Cells
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Hong JY, Park SH, Park HJ, Lee SK
- KMID: 2417368
- J Cancer Prev.
- 2018 Jun;23(2):63-69.
- doi: 10.15430/JCP.2018.23.2.63
BACKGROUND: 15,16-dihydrotanshinone I (DHTS) is a natural abietane diterpenoid that is mainly found in the roots of Salvia miltiorrhiza Bunge (Labiatae). DHTS exhibits a potential anti-proliferative effect in various human... -
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- Is 5'-AMP-Activated Protein Kinase Both Jekyll and Hyde in Bladder Cancer?
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Kim WJ
- KMID: 2380829
- Int Neurourol J.
- 2015 Jun;19(2):55-66.
- doi: 10.5213/inj.2015.19.2.55
The 5'-AMP-activated protein kinase (AMPK) is a key regulator of cellular metabolism and energy homeostasis in mammalian tissues. Metabolic adaptation is a critical step in ensuring cell survival during metabolic... -
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- AMP-activated protein kinase as a key molecular link between metabolism and clockwork
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Lee Y, Kim EK
- KMID: 2154252
- Exp Mol Med.
- 2013 Jul;45(7):e33.
Circadian clocks regulate behavioral, physiological and biochemical processes in a day/night cycle. Circadian oscillators have an essential role in the coordination of physiological processes with the cyclic changes in the... -
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- AMPK activators: mechanisms of action and physiological activities
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Kim J, Yang G, Kim Y, Kim J, Ha J
- KMID: 2361511
- Exp Mol Med.
- 2016 Apr;48(4):e224.
- doi: 10.1038/emm.2016.16
AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis, which coordinates metabolic pathways and thus balances nutrient supply with energy demand. Because of the favorable physiological outcomes of... -
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