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Relative biological effectiveness of fast neutrons for apoptosis in mouse hair follicles

Lee HJ, Kim SH

This study compared the effects of high linear energy transfer (LET) fast neutrons on the induction of apoptosis in the hair follicles of ICR mice with those of low LET...
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Cytotoxicity of gamma-ray in rat immature hippocampal neurons

Yang M, Song MS, Kim SH, Kim JC, Kim JS, Shin T, Moon C

This in vitro study evaluated the detrimental effect of acute gamma (gamma)-irradiation on rat immature hippocampal neurons. Rat immature hippocampal neurons (0.5 day in vitro) were irradiated with 0~4 Gy...
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Phytotherapeutic effects of Echinacea purpurea in gamma-irradiated mice

Abouelella AM, Shahein YE, Tawfik SS, Zahran AM

Echinacea (E.) purpurea herb is commonly known as the purple coneflower, red sunflower and rudbeckia. In this paper, we report the curative efficacy of an Echinacea extract in gamma-irradiated mice....
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Ionizing radiation induces blockade of c-Jun N-terminal kinasedependent cell death pathway in amanner correlated with p21Cip/WAF1 induction in primary cultured normal human fibroblasts

Cho ES, Lee SB, Bae IH, Lee YS, Lee SJ, Um HD

  • KMID: 1093463
  • Exp Mol Med.
  • 2005 Aug;37(4):282-289.
During radiotherapy of cancer, neighboring normal cells may receive sub-lethal doses of radiation. To investigate whether such low levels of radiation modulate normal cell responses to death stimuli, primary cultured...
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Comparison of Resistance to gamma-Irradiation between Cryptosporidium parvum and Cryptosporidium muris Using In Vivo Infection

Yoon S, Yu JR

In the genus Cryptosporidium, there are more than 14 species with different sizes and habitats, as well as different hosts. Among these, C. parvum and C. hominis are known to...
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Quantitative Evaluation of Infectivity Change of Cryptosporidium parvum after Gamma Irradiation

Lee SU, Joung M, Nam T, Park WY, Yu JR

Cryptosporidium parvum is a well-known waterborne and opportunistic intracellular protozoan parasite that causes diarrheal illness. In this study, we quantitatively investigated reduction of the infectivity of C. parvum after gamma...
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Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells

Choi YJ, Kim SY, Oh JM, Juhnn YS

Stimulatory heterotrimeric GTP-binding proteins (Gs protein) stimulate cAMP generation in response to various signals, and modulate various cellular phenomena such as proliferation and apoptosis. This study aimed to investigate the...
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P53 expression in hepatocellular carcinoma: influence on the radiotherapeutic response of the hepatocellular carcinoma

Lee YR, Park SY

No abstract available.
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Influence of gestational age at exposure on the prenatal effects of gamma-radiation

Kim SH, Kim SR, Lee YS, Kim TH, Jo SK, Lee CS

  • KMID: 1103504
  • J Vet Sci.
  • 2001 Apr;2(1):37-42.
The objective of this investigation was to evaluate the influence of gestational age at exposure on the prenatal effects of gamma-radiation. Pregnant ICR mice were exposed to a single dose...
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Dose-Incidence Relationships on the Prenatal Effects of Gamma-Radiation in Mice

Bang DW, Lee JH, Oh H, Kim SR, Kim TH, Lee YS, Lee CS, Kim SH

  • KMID: 1101568
  • J Vet Sci.
  • 2002 Mar;3(1):7-11.
The objective of this investigation was to evaluate dose-incidence relationships on the prenatal effects of gamma-radiation. Pregnant ICR mice were exposed on day 11.5 after conception, coincident with the most...
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Knockdown of 14-3-3zeta enhances radiosensitivity and radio-induced apoptosis in CD133+ liver cancer stem cells

Lee YK, Hur W, Lee SW, Hong SW, Kim SW, Choi JE, Yoon SK

14-3-3zeta is related to many cancer survival cellular processes. In a previous study, we showed that silencing 14-3-3zeta decreases the resistance of hepatocellular carcinoma (HCC) to chemotherapy. In this study,...
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Influence of P53 on the radiotherapy response of hepatocellular carcinoma

Gomes AR, Abrantes A, Brito AF, Laranjo M, Casalta-Lopes JE, Goncalves , Sarmento-Ribeiro AB, Botelho MF, Tralhao JG

BACKGROUND/AIMS: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it has a poor prognosis and few therapeutic options. Radiotherapy is one of the most effective forms...
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