Korean J Hepatol.
2002 Sep;8(3):317-320.
A Case of Acute Cholestatic Hepatitis Associated with Orlistat
- Affiliations
-
- 1Department of Gastroenterology, Ajou University College of Medicine, Suwon, Korea. sung-woncho@hotmail.com
- 2Department of Histopathology, Ajou University College of Medicine, Suwon, Korea.
Abstract
- Orlistat(Xenical(R), Roche) is considered a safe and effective drug to treat obesity by reduced absorption of 30% digested fat. To date, no serious adverse effects affecting the liver have been published except a case of subacute hepatic failure leading to liver transplantation in a young women with moderate obesity treated with orlistat. We report a case of acute cholestatic hepatitis in a young woman with moderate obesity treated with orlistat: a 33-year-old female admitted for the evaluation of jaundice. Abdominal ultrasonography, ERCP, routine chemistry, viral markers, and a fine needle biopsy of liver were performed. Microscopic findings of the liver biopsy specimen were compatible with acute cholestatic hepatitis. After steroid therapy, liver function was improved.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- A Case of Acute Q Fever with Severe Acute Cholestatic Hepatitis
- A Case of Steven-Johnson Syndroe Associated with Cholestatic Hepatitis
- "Soju Remedy", and Chinese Herb-Induced Cholestatic Hepatitis
- An Unusual Combination of Relapsing and Cholestatic Hepatitis A in Childhood
- A Case of Cholestatic Hepatitis Induced by Epstein-Barr Virus Infection
