Korean J Gastroenterol.
2006 Oct;48(4):277-280.
A Case of Primary Neuroendocrine Carcinoma of Liver Presenting with Liver Abscess
- Affiliations
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- 1Departments of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea. kakim@ilsanpaik.ac.kr
- 2Departments of Pathology, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.
Abstract
- Primary hepatic neuroendocrine cell carcinoma is a very rare tumor. We experienced a 75-year-old woman with primary hepatic neuroendocrine carcinoma presenting with pyogenic liver abscess. Abdominal CT scan revealed a multiseptated liver abscess and an enlarged lymph node in portocaval portion. We performed percutaneous drainage of the liver abscess, but the amount of drained pus did not decrease after 20 days. The follow-up abdominal CT scan showed that the cystic portion of liver abscess had been replaced by the solid tumor. Microscopic examination of the tumor tissue showed nests of epithelial cells with uniform round hyperchromatic nuclei and high nuclear to cytoplasmic ratio. Immunohistochemical staining was strongly positive for synaptophysin and chromogranin A.
Keyword
MeSH Terms
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Adenine/analogs & derivatives/therapeutic use
Antiviral Agents/*adverse effects/therapeutic use
Drug Eruptions/diagnosis/*pathology
Female
Hepatitis B, Chronic/*drug therapy
Humans
Ichthyosis/chemically induced/pathology
Lamivudine/*adverse effects/therapeutic use
Middle Aged
Phosphonic Acids/therapeutic use
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