Yonsei Med J.  2001 Jun;42(3):352-356. 10.3349/ymj.2001.42.3.352.

A Case of Hemorrhagic Gallbladder Paraganglioma Causing Acute Cholecystitis

• Cho YU
• Kim JY
• Choi SK
• Hur YS
• Lee KY
• Kim SJ
• Ahn SI
• Hong KC
• Woo ZH
• Han JY
• Shin SH

• KMID: 720634
• DOI: http://doi.org/10.3349/ymj.2001.42.3.352

Abstract

Gallbladder paraganglioma is a very rare tumor and so far only a few cases have been reported. Most of these were asymptomatic and were found incidentally during operation. Recently, we experienced a gallbladder paraganglioma that gave rise to hemorrhage, which in turn caused acute cholecystitis. Our case involved a 45 year-old female patient complaining of an intermittent right upper abdominal pain. After a preoperative evaluation, cholecystectomy and lymphadenectomy were performed under the impression of gallbladder cancer with acute cholecystitis. Postoperative pathologic examination revealed a hemorrhagic gallbladder paraganglioma accompanied by acute cholecystitis. Immunohistochemical staining of the chief cells for neuron specific enolase, chromogranin and synaptophysin were positive. Sustentacular cells also stained positively for S100 protein.

Keyword

Paraganglioma; gallbladder; acute cholecystitis

MeSH Terms

Acute Disease
Case Report
Cholecystitis/*etiology
Female
Gallbladder Neoplasms/*complications/pathology
Hemorrhage/*complications
Human
Immunohistochemistry
Middle Age
Paraganglioma/*complications/pathology