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T-cell Large Granular Lymphocytic Leukemia Presenting as Post-transplant Lymphoproliferative Disorder: A Report of Two Cases and Literature Review

Kim S, Cho YU, Jang S, Seo EJ, Park CJ

T-cell large granular lymphocytic leukemia (T-LGLL) can present as a form of post-transplant lymphoproliferative disorder. Here, we described clinicopathological findings from 58 cases of post-transplant T-LGLL (our own 2 cases...
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Immune Checkpoint Programmed Cell Death Protein-1 (PD-1) Expression on Bone Marrow T Cell Subsets in Patients With Plasma Cell Myeloma

Lee MY, Park CJ, Cho YU, You E, Jang S, Seo EJ, Lee JH, Yoon DH, Suh C

Background: Plasma cell myeloma (PCM) is caused by immune dysregulation. We evaluated the expression of immune checkpoint programmed cell death protein-1 (PD-1) on T cell subsets in PCM patients according...
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Revised World Health Organization Criteria-Defined Acute Myeloid Leukemia in a Large Cohort: Highlighting the Frequency and Characterization of Recategorized Cases

Kim S, Lee MY, Cho YU, Hwang SH, Jang S, Seo EJ, Park CJ

Background: Application of the 2016 revised WHO criteria for categorization of acute myeloid leukemia (AML) highlights certain discrepancies from that of the 2008 WHO criteria. We thus analyzed the frequency,...
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Survival Rates of Breast Cancer Patients Aged 40 to 49 Years according to Detection Modality in Korea: Screening Ultrasound versus Mammography

Won SY, Park HS, Kim P, Kim SI, Moon HJ, Yoon JH, Park VY, Park S, Kim MJ, Cho YU, Park BW

Objective: The aim of this study was to compare the survival rates of Korean females aged 40 to 49 years with breast cancer detected by supplemental screening ultrasound (US) or...
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Status of Next-Generation Sequencing-Based Genetic Diagnosis in Hematologic Malignancies in Korea (2017-2018)

Kim J, Lee JY, Huh J, Nam MH, Kim M, Cho YU, Kong SY, Lee ST, Kim IS

Background: The aim of this study was to investigate the status of next generation sequencing (NGS)-based genetic diagnosis in hematologic malignancies in Korea in 2017 and 2018. Methods: A structured questionnaire...
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Clinical, Laboratory, and Bone Marrow Findings of 31 Patients With Waldenström Macroglobulinemia

Ahn A, Park CJ, Cho YU, Jang S, Seo EJ, Lee JH, Yoon DH, Suh C

BACKGROUND: Waldenström macroglobulinemia (WM) is a subset of lymphoplasmacytic lymphoma (LPL) with bone marrow (BM) involvement and an IgM monoclonal gammopathy of any level. We aimed to identify the clinical,...
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Assessment of the Prognostic Staging System of American Joint Committee on Cancer 8th Edition for Breast Cancer: Comparisons with the Conventional Anatomic Staging System

Kim EJ, Park HS, Kim JY, Kim SI, Cho YU, Park BW

PURPOSE: The 8th edition of the American Joint Committee on Cancer (AJCC) staging manual introduced a new prognostic staging system for breast cancer. This study aimed to evaluate the changes...
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Performance Evaluation of the CS-5100 Coagulation Analyzer for Special Coagulation Parameters

Kim B, Jang S, Lee YJ, Park N, Cho YU, Park CJ

BACKGROUND: The CS-5100 high-throughput automated coagulometer (Sysmex, Japan) can perform general and special coagulation assays. We evaluated the performance of the CS-5100 coagulometer to measure fibrinogen degradation product (FDP), plasma...
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Revision of Laboratory Testing Guidelines for Initial Diagnosis of Hematologic Neoplasms

Kim IS, Lee JY, Kong SY, Lee ST, Huh J, Nam MH, Kim M, Cho YU, Huh HJ, Song J, Park H

The standardization committee of the Korean Society for Laboratory Hematology revised laboratory testing guidelines in order that hematologic neoplasms could be diagnosed according to the revised 4th edition of WHO...
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The First Korean Case of Epstein-Barr Virus-positive Natural Killer/T-cell Lymphoma That Progressed From Severe Mosquito Bite Allergy, With Coexistence of Hemophagocytic Lymphohistiocytosis

Lee S, Park CJ, Cho YU, Jang S, Huh J, Kim H

No abstract available.
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First Case of Double T-Cell Receptor Alpha/Delta Rearrangements of t(11;14) and inv(14) and Subsequent JAK2 Rearrangement in a Patient With T-cell Acute Lymphoblastic Leukemia

Seol CA, Cho YU, Jang S, Park CJ, Lee JH, Seo EJ

No abstract available.
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JL1 Antigen Expression on Bone Marrow Lymphoma Cells from Patients With Non-Hodgkin Lymphoma

Kim MS, Park CJ, Cho YU, Jang S, Seo EJ, Park CS, Huh J, Im HJ, Seo JJ, Yoon DH, Suh C

BACKGROUND: JL1, a CD43 epitope and mucin family cell surface glycoprotein, is expressed on leukemic cells. An anti-JL1 antibody combined with a toxic substance can have targeted therapeutic effects against...
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An Updated Nomogram for Predicting Invasiveness in Preoperative Ductal Carcinoma In Situ of the Breast

Kim S, Kim J, Park HS, Kim HY, Lee K, Lee J, Lee H, Kim JY, Kim SI, Cho YU, Park BW

PURPOSE: To validate and update a nomogram for predicting ductal carcinoma in situ (DCIS) upstaging in preoperative biopsy. MATERIALS AND METHODS: Medical records of 444 preoperative DCIS patients were evaluated and...
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POEMS Syndrome: Bone Marrow, Laboratory, and Clinical Findings in 24 Korean Patients

Shim H, Seol CA, Park CJ, Cho YU, Seo EJ, Lee JH, Yoon DH, Suh CW, Park SH, Jang S

POEMS syndrome is a rare paraneoplastic syndrome, which includes polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes due to plasma cell (PC) neoplasm. Diagnosis of this disease is challenging because of...
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Two Rare Cases of Therapy-Related Acute Lymphoblastic Leukemia in Patients With Plasma Cell Myeloma

Lee HY, Park CJ, Ahn A, Lee MY, Cho YU, Jang S, Seo EJ, Lee KH, Lee JH

No abstract available.
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Is the frozen section examination for sentinel lymph node necessary in early breast cancer patients?

Yoon KH, Park S, Kim JY, Park HS, Kim SI, Cho YU, Park BW

PURPOSE: Sentinel lymph node (SLN) biopsy (SLNB) is widely performed for axillary staging in patients with breast cancer. Based on the results of frozen section examination (FSE), surgeons can decide...
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Unique Red Blood Cell Morphology Detected in a Patient with Myelodysplastic Syndrome by Three-dimensional Refractive Index Tomography

Koo SE, Jang S, Park CJ, Cho YU, Park Y

The three-dimensional (3-D) shape of erythrocytes is strongly associated with various diseases. However, conventional optical imaging approaches with Wright's staining only provide information on two-dimensional morphology. Here, we employed optical...
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Recommendation for the Peripheral Blood Cell Morphology Report

Kwon JA, Kim YG, Park G, Kim JM, Cho YU, Huh J, Kong SY, Han JY, Yoon SY

There is considerable heterogeneity in the peripheral blood smear reports across different diagnostic laboratories, despite following the guidelines published by the International Council for Standardization in Haematology (ICSH). As standardization...
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The Incidence and Immunophenotypic and Genetic Features of JL1 Expressing Cells and the Therapeutic Potential of an Anti-JL1 Antibody in De Novo Pediatric Acute Leukemias

Park SH, You E, Park CJ, Jang S, Cho YU, Yoon CH, Koh KN, Im HJ, Seo JJ

BACKGROUND: JL1 is a newly identified CD43 epitope that specifically recognizes leukemic cells. We analyzed the incidence of JL1 expression and compared the clinical, immunophenotypic, and genetic characteristics of de...
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A Phase II Study to Evaluate the Safety and Efficacy of Pegteograstim in Korean Breast Cancer Patients Receiving Dose-Dense Doxorubicin/Cyclophosphamide

Kim GM, Kim JH, Kim JH, Cho YU, Kim SI, Park S, Park HS, Kim JY, Sohn J

PURPOSE: Dose-dense chemotherapy (DD-CT) is a preferred (neo)adjuvant regimen in early breast cancer (BC). Although the results of reported randomized trials are conflicting, a recent meta-analysis showed improved overall and...
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