Yonsei Med J.  1997 Aug;38(4):236-239. 10.3349/ymj.1997.38.4.236.

Acute monoarthritis associated with positively birefringent maltese cross appearing lipid spherules in a hyperlipidemic diabetic patient

Affiliations
  • 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Abstract

A 63-year old man developed acute monoarthritis in the dorsum of the left foot. Polarized light microscopy of the synovial fluid from his third metatarsophalangeal joint revealed numerous positively birefringent lipid spherules with a maltese cross appearance. Positively birefringent lipid spherules can be found in association with acute, otherwise unexplained arthritis, and may induce synovial inflammation similar to that seen in other types of crystal-induced arthritis. We report a case of acute monoarthritis in which large numbers of positively birefringent lipid spherules were present in a hyperlipidemic diabetic patient.

Keyword

Positively birefringent lipid spherule; hyperlipidemia; arthritis

MeSH Terms

Acute Disease
Arthritis/metabolism*
Arthritis/complications*
Birefringence
Case Report
Crystallization
Diabetes Mellitus/blood*
Human
Hyperlipidemia/complications*
Lipids/metabolism*
Male
Middle Age
Synovial Fluid/metabolism*
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