J Stroke.  2025 Jan;27(1):122-127. 10.5853/jos.2024.03944.

Parkinsonism in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy: Clinical Features and Biomarkers

Affiliations
  • 1Department of Neurology, National Taiwan University Hospital, Taipei, Taiwan
  • 2Department of Medical Imaging, National Taiwan University Hospital, Taipei, Taiwan
  • 3Department of Neurology, National Taiwan University Hospital Jinshan Branch, New Taipei City, Taiwan
  • 4Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan
  • 5Graduate Institute of Molecular Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan
  • 6Department of Biomedical Engineering, National Taiwan University, Taipei, Taiwan


Figure

  • Figure 1. Clinical features and biomarkers of parkinsonism in CADASIL patients. (A) Exemplar brain MRI results in CADASIL patients with parkinsonism at different H-Y stages. Comparisons between CADASIL patients with parkinsonism (CAD) and idiopathic Parkinson’s disease patients (IPD). (B) UPDRS-III category score. (C) Alpha-synuclein level at different H-Y stages. MRI, magnetic resonance imaging; CADASIL, cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy; H-Y, Hoehn-Yahr; UPDRS-III, Unified Parkinson’s Disease Rating Scale part III.


Reference

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