J Stroke.  2025 Jan;27(1):113-117. 10.5853/jos.2024.03062.

Thrombolysis in Patients With Versus Without Visible Occlusion: A Secondary Analysis From the AcT Trial

Affiliations
  • 1Division of Neurology, Rady Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada
  • 2Department of Clinical Neurosciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada
  • 3Division of Neurology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • 4Department of Radiology, Tours University Hospital, Tours, France
  • 5Department of Community Health Sciences and O’Brien Institute for Public Health, University of Calgary, Calgary, AB, Canada
  • 6Kelowna General Hospital, Kelowna, BC, Canada
  • 7Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB, Canada
  • 8Hamilton Health Sciences and McMaster University, Hamilton, ON, Canada
  • 9University of Saskatchewan, Saskatoon, SK, Canada
  • 10Division of Neurology, Department of Medicine, Ottawa Hospital Research Institute and University of Ottawa, Ottawa, ON, Canada
  • 11St. Michael’s Hospital, Toronto, ON, Canada
  • 12Vancouver Stroke Program and the Division of Neurology, University of British Columbia, Vancouver, BC, Canada
  • 13Division of Neurology, Department of Medicine, Queen’s University, Kingston, ON, Canada
  • 14Division of Neurology, Department of Medicine, Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
  • 15Department of Radiology, University of Calgary, Calgary, AB, Canada
  • 16Hotchkiss Brain Institute, Calgary, AB, Canada


Figure

  • Figure 1. Hemorrhage rates and functional outcomes in patients with no visible occlusion versus those with visible occlusion. (A) Hemorrhage rates as per Heidelberg classification by visible occlusion status (yes/no). (B) Outcome by visible occlusion status (yes/no). ICH, intracranial hemorrhage; sICH, symptomatic intracerebral hemorrhage; HI1, hemorrhagic Infarction type 1; HI2, hemorrhagic Infarction type 2; PH1, parenchymal hematoma type 1; PH2, parenchymal hematoma type 2; rPH1, remote parenchymal hematoma type 1; rPH2, remote parenchymal hematoma type 2; SDH, subdural hemorrhage; SAH, subarachnoid hemorrhage; IVH, intraventricular hemorrhage; mRS, modified Rankin Scale.


Reference

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