Clin Ultrasound.  2024 Nov;9(2):91-95. 10.18525/cu.2024.9.2.91.

Keratinizing Squamous Cell Carcinoma of Gallbladder Presenting as Hepatic Abscess

• Han SK
• Kim T
• Kim MY

• KMID: 2561487
• DOI: http://doi.org/10.18525/cu.2024.9.2.91

Abstract

Gallbladder tumors are rare but aggressive malignancies, often identified incidentally after cholecystectomy. Adenocarcinoma is the most common phenotype, though squamous cell carcinoma is rare, and it ranged as 1–4% of reported gallbladder cancer. Due to the rarity of the disease, early diagnosis is often challenging. One of the uncommon presentations of gallbladder cancer is hepatic abscess, with few cases reported in the literature. This report presents a rare case of an 82-year-old male referred with hepatic abscess. Multiple pathogens were isolated, indicating a superimposed bacterial infection. Upon further investigation, cytology confirmed the presence of a keratinizing squamous carcinoma of gallbladder cancer. This case presents a rare instance of squamous cell gallbladder carcinoma, which is difficult to diagnose, discovered in an elderly patient who presented with a liver abscess accompanied by bacterial infection. It highlights the challenges in diagnosis and treatment, as well as the poor prognosis associated with the condition.

Keyword

Gallbladder cancer; Squamous cell carcinoma; Liver abscess; 담낭암; 편평상피세포암; 간농양