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Three Cases of Vulvar Squamous Cell Carcinoma Arising from Lichen Sclerosus

Song JY, Yun SJ

  • KMID: 2548464
  • Korean J Dermatol.
  • 2023 Nov;61(9):582-585.
Vulvar lichen sclerosus (LS) is a chronic inflammatory dermatosis and is considered a precursor lesion of squamous cell carcinoma (SCC); with about 3% to 5% of cases progressing to SCC,...
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Local Rotatory Flap Reconstruction After Treatment of Auricular Squamous Cell Carcinoma

Hong JP, Kim KN, Kim MB

Complete surgical removal of tumor is a main treatment strategy of auricular squamous cell carcinoma (SCC). However, the appropriate reconstruction of the defect should also be carefully planned because of...
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Squamous cell carcinoma of lower lip: the results of wide V-shaped resection

Youn SB, Myoung H, Kwon IJ

Generally, if the size of a lip cancer defect exceeds 30% of the lower lip, a local flap or free flap is recommended. However, defects up to 50% of the...
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Modified cervicofacial transposition flap: a case report of aesthetic considerations after resection of a huge facial squamous cell carcinoma

Kim YJ, Cheon JS, Choi MH, Choi WY

The cheek, a highly visible and significant aspect of an individual’s appearance, is situated adjacent to several structures involved in facial expressions, including the eye, mouth, and surrounding facial muscles....
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Predicting recurrence in oral cavity cancers: a review of 116 patients with buccal mucosa carcinoma in northwestern India

Patel P, Singhal PM, Lakhera KK, Chatterjee A, Babu A, Singh S, Sharma S, Gora BS, Agarwal NK

Background: Oral cavity cancers, the second most common type in India, are responsible for 10% of the overall cancer burden. With a recurrence rate of 30% to 40% and a...
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Phase II Trial of Combined Durvalumab Plus Tremelimumab with Proton Therapy for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Kim H, Park S, Jung HA, Lee SH, Park K, Ahn YC, Oh D, Ahn MJ

Purpose This phase II study investigated whether durvalumab/tremelimumab with proton therapy improves the objective response rate (ORR), overall survival (OS), and progression-free survival (PFS) in heavily treated recurrent or metastatic...
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Outcomes of Salvage Therapy for Oropharyngeal Cancer Recurrence Following Upfront Radiation Therapy and Prognostic Factors

Choi N, Kim HJ, Yi H, Kim H, Kim TH, Jeong HS, Son YI, Baek CH, Oh D, Ahn YC, Chung MK

Purpose This study aimed to investigate the oncologic outcomes and prognostic factors of salvage treatments in patients with recurrent oropharyngeal squamous cell carcinoma (OPSCC) after radiotherapy (RT)-based treatment. Materials and Methods...
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Squamous Cell Carcinoma Occurring at the Site of an Arteriovenous Fistula Ulcer: A Case Report

Kang HE, Jeong SMG, Kim CY

  • KMID: 2546603
  • Korean J Dermatol.
  • 2023 Sep;61(8):506-508.
Marjolin’s ulcer is a malignant skin tumor that arises at the site of scars, chronic ulcerations, inflammations, and fistulas after a long latent period. These tumors are mostly squamous cell...
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Pretreatment total lymphocyte count as a prognostic factor of survival in patients with recurrent cervical cancer after definitive radiation-based therapy: a retrospective study

Thiangphak E, Leetanaporn K, Buhachat R

Objective This study evaluated the association between pretreatment total lymphocyte count (TLC) and overall survival (OS) in patients with recurrent cervical cancer. Methods We retrospectively reviewed 290 patients with recurrent cervical...
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Bone-Invaded Squamous Cell Carcinoma with Aggressive Behavior

Shin BS, Seo JH, Choi H, Na CH, Kim MS

  • KMID: 2545744
  • Korean J Dermatol.
  • 2023 Aug;61(7):447-451.
Cutaneous squamous cell carcinoma is the second most common tumor in humans, and its incidence is increasing. In cutaneous squamous cell carcinoma, lymph node and distant metastases are rare, and...
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Oncologic Outcomes of T1–T2N0 Glottic Cancer Treatment: Single Center Experiences of 417 Patients Over 20 Years

Choi SY, Chung MK, Ahn YC, Oh D, Son YI

Background and Objectives For T1–T2 early glottic cancer, single modality treatment with radiation therapy (RT) or transoral laser microsurgery is the standard therapeutic option. However, the choice between surgery and...
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Esophageal Cancer and Sex Hormones

Kim YJ

Globally, esophageal cancer is the seventh most common cancer, and the male-to-female ratio in esophageal adenocarcinoma (EAC) is significantly imbalanced at 4:1 to 8:1. Obesity, reflux, and smoking are known...
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A Case of Squamous Cell Carcinoma of Nasal Septum Removed Through the External Rhinoplasty Approach

Lee SH, Park JH, Lee DB, Lee SH

Primary tumors arising solely from the nasal septum are quite unusual. Moreover, malignant tumors arising from the nasal septum are rare and represent less than 9% of sinonasal malignancies. Of...
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A Comparative Clinicopathological Study of Inverted Follicular Keratosis and Well-Differentiated Squamous Cell Carcinoma

Yim JE, Shin DH, Choi JS, Bae YK

  • KMID: 2544981
  • Korean J Dermatol.
  • 2023 Jul;61(6):352-359.
Background: Inverted follicular keratosis (IFK) is a benign tumor that occurs mainly as a single lesion in the head and neck. Histologically, the tumor lobules show endophytic or exophytic growth...
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Intrathyroidal metastasis of tonsillar squamous cell carcinoma masquerading as a primary thyroid tumor

Go JH

Intrathyroidal metastasis of tonsillar squamous cell carcinoma is rare. To date, only six cases have been reported in the literature. This case was unusual and presented with thyromegaly before the...
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A Case of Acantholytic Squamous Cell Carcinoma on a Male Areola: An Uncommon Histologic Variant at a Rare Location

Kim JH, Uh JA, Kim HS, Lee SK, Kim MS, Gwak G, Lee UH

  • KMID: 2543891
  • Korean J Dermatol.
  • 2023 Jun;61(5):308-312.
The areola is a rare location for squamous cell carcinoma (SCC) because sunlight exposure, the main risk factor for SCC, is unusual on it. Acantholytic SCC (ASCC) is a rare...
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A Case of Merkel Cell Polyomavirus-Negative Merkel Cell Carcinoma Concurrent with Squamous Cell Carcinoma

Lee KJ, An HY, Choi SJ, Hwang HW, Lee SB, Shin HT, Shin J, Choi GS, Byun JW

  • KMID: 2542616
  • Korean J Dermatol.
  • 2023 May;61(4):239-243.
Merkel cell carcinoma (MCC), a rare cutaneous neuroendocrine carcinoma, is most common in sun-exposed areas of aged individuals. Merkel cell polyomavirus (MCPyV) is one causative agent of MCC. Cases of...
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Squamous Cell Carcinoma Arising from Epidermal Inclusion Cyst of Breast: Imaging Findings and Literature Review

Han Yj, Kim YM

Commonly, epidermal inclusion cysts (EICs) are benign cutaneous lesions that are lined with stratified squamous epithelium and may occur in all body parts, including the breasts. EICs in the breast...
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Efficacy of endoscopy under general anesthesia for the detection of synchronous lesions in oro-hypopharyngeal cancer

Ono Y, Yao K, Takaki Y, Ishikawa S, Imamura K, Koga A, Ohtsu K, Kanemitsu T, Miyaoka M, Hisabe T, Ueki T, Ota A, Tanabe H, Haraoka S, Nimura S, Iwashita A, Sato S, Wakasaki R

Background/Aims: Image-enhanced endoscopy can detect superficial oro-hypopharyngeal squamous cell carcinoma; however, reliable endoscopy of the pharyngeal region is challenging. Endoscopy under general anesthesia during transoral surgery occasionally reveals multiple synchronous...
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Pitavastatin Induces Apoptosis of Cutaneous Squamous Cell Carcinoma Cells through Geranylgeranyl PyrophosphateDependent c-Jun N-Terminal Kinase Activation

Kim KI, Kim SM, Lee YY, Lee Y, Kim CD, Yoon TJ

Background: Pitavastatin is a cholesterol-lowering drug and is widely used clinically. In addition to this effect, pitavastatin has shown the potential to induce apoptosis in cutaneous squamous cell carcinoma (SCC)...
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