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Ann Clin Neurophysiol.  2024 Oct;26(2):54-56. 10.14253/acn.24001.

Early relapse after rituximab treatment in a patient with seronegative neuromyelitis optica spectrum disorder: a case report

Affiliations
  • 1Department of Neurology, Kangwon National University Hospital, Chuncheon, Korea
  • 2Department of Translational Medicine, Seoul National University College of Medicine, Seoul, Korea
  • 3Department of Neurology, Seoul National University Seoul Metropolitan Government Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea

Abstract

Rituximab (RTX) is a monoclonal antibody that targets CD20 on B cells and is used to reduce the relapse risk in neuromyelitis optica spectrum disorder (NMOSD). Some patients experience relapse or exacerbation shortly after RTX treatment. We report a 54-year-old female with seronegative NMOSD who relapsed soon after RTX treatment.

Keyword

Neuromyelitis optica spectrum disorder; Neuromyelitis optica spectrum disorder; Rituximab; Recurrence; Rituximab; Recurrence
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