Korean J Transplant.  2023 Nov;37(Suppl 1):S215. 10.4285/ATW2023.F-8057.

Cardiovascular events after kidney transplantation

• Lee S
• Moon KY
• Jang EJ
• Han HS
• Park SC
• Yun SS
• Kim JY

• KMID: 2551835
• DOI: http://doi.org/10.4285/ATW2023.F-8057

Abstract

Background
End-stage renal disease patients are at a higher risk of cardiovascular diseases, and it is the leading cause of death. Kidney transplantation (KT) has the advantage of reducing the cardiovascular risk by discontinuing dialysis, although there is a risk of general anesthesia and patient deterioration due to surgical complications during postoperative care. We aimed to evaluate the cardiovascular events and the risk factors of such events after KT at a single center.
Methods
This study was conducted on patients who received KT from January 2017 to July 2022 at Seoul St. Mary’s Hospital. A total of 931 patients were included. Mean age was 49.75 (standard deviation [SD], 11.6) years, 567 patients were male, 629 patients had hypertension, 291 patients had diabetes, and mean body mass index (BMI) was 23.3 (SD, 4.43). Patients who had major adverse cardiovascular events (myocardial infarction, stroke, heart failure, coronary revascularization, atrial fibrillation, cardiovascular disease death) during follow-up were investigated for risk factors. Thirty-nine patients showed cardiovascular events. Chi-square test and independent sample t-test were used for statistical analysis.
Results
There were 39 (4.2%) of 931 patients who had cardiovascular events. Eighteen patients had ischemic stroke, and 21 patients required coronary revascularization. Our study showed that age (P<0.05), dialysis duration (P<0.05) showed statistical significance with cardiovascular event. Diabetes mellitus (P=0.464), hypertension (P=0.571), and BMI (P=0.385) did not show statistical significance.
Conclusions
The prevalence of cardiovascular event was 4.2% at our center. Patient age at transplantation and duration of dialysis were found to be statistically significant.