Ewha Med J.  2015 Mar;38(1):7-13. 10.12771/emj.2015.38.1.7.

ABO-Incompatible Kidney Transplantation

  • 1Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea. dhkang@ewha.ac.kr


Kidney transplantation is the best treatment for end-stage renal disease patients. However, the relative shortage of organs for transplantation has led to ABO-incompatible kidney transplantation as an accepted method to expand the pool of kidney donors. Recent advances in immunosuppression and antibody removal methods have made ABO-incompatible kidney transplantation more feasible, and have increased the opportunities for patients to receive kidney transplantation, as well as for special patients with ABO-compatible donor. Indeed, the outcome of ABO-incompatible kidney transplantation has shown remarkable developments and is now comparable to that of ABO-compatible kidney transplantation during last decade. However, there are still some uncertain issues to be addressed in ABO-incompatible kidney transplantation. In this article, we reviewed the current status and protocol of ABO-incompatible kidney transplantation and listed the concerns to be addressed in near future.


Blood group incompatibility; Kidney transplantation; Immunosuppression; Antibodies
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