Ann Lab Med.  2023 May;43(3):303-306. 10.3343/alm.2023.43.3.303.

A Rare Case of Extensive Erythrophagocytosis by Pathological Erythroblasts in a Patient With Myelodysplastic Syndrome

• Qiang X
• Li J
• Chen S
• Gou Y
• Wang P
• Chen X

• KMID: 2551716
• DOI: http://doi.org/10.3343/alm.2023.43.3.303

Figure

• 

  Fig. 1 Results of bone marrow aspirate analysis. (A, B) Bone marrow smears showing pathological erythroblasts with distinct cytoplasmic vacuoles that had phagocytized both an erythrocyte and a late erythroblast. (C) Pathological erythroblasts exhibiting strongly positive periodic acid-Schiff staining. (D) Ring sideroblasts were evident in iron staining(Indicated by black arrows). (E) Phagocytized erythrocytes were negatively stained for myeloperoxidase (Indicated by black arrows).

• 

  Fig. 2 Flow cytometry-based immunophenotyping results. Brown dots indicate an increased frequency of erythroid cells (up to 41.21%) that were positive for CD71 and CD235a and negative for CD36.

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