J Korean Med Sci.  2023 Dec;38(50):e419. 10.3346/jkms.2023.38.e419.

Significant Gap Between Guidelines and Practice in the Management of LDL Cholesterol: Insight From the Survey of the Korean Society of Myocardial Infarction

Affiliations
  • 1Division of Cardiology, Chung-Ang University Gwangmyeong Hospital, Gwangmyeong, Korea
  • 2Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
  • 3Department of Cardiology, Chonnam National University Medical School, Chonnam National University Hospital, Gwangju, Korea
  • 4Department of Internal Medicine, Kyungpook National University Hospital, Daegu, Korea
  • 5Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
  • 6Department of Internal Medicine, College of Medicine, Gyeongsang National University and Hospital, Jinju, Korea
  • 7Department of Cardiovascular Medicine, Kyung Hee University Hospital, Seoul, Korea

Abstract

The Guidelines of the 2019 European Society of Cardiology (ESC) and the 5th Society of Lipid and Atherosclerosis (KSoLA) for the Management of Dyslipidemia advocate a more intensive lipid-lowering strategy. However, there is a lack of evidence regarding the current status of lipid management in Korean patients in real-world practice. The Korean Society of Myocardial Infarction conducted a survey among its members of the Korean Society of Cardiology on the new lipid guidelines. Although most participants were aware of the changes in the ESC and the KSoLA guidelines, more than half of them did not agree with lowering the low-density lipoprotein cholesterol levels to < 55 mg/dL, because its safety and efficacy have not yet been proven in Koreans. A substantial disparity exists between lipid management guidelines and current clinical practices, highlighting the necessity for clinical research that specifically targets East Asians and Koreans to bridge this gap.

Keyword

Dyslipidemias; Myocardial Infarction; Cholesterol; Low-density Lipoprotein Cholesterol

Figure

  • Fig. 1 What is your LDL-C goal in patients with acute myocardial infarction?LDL-C = low-density lipoprotein cholesterol.

  • Fig. 2 Why are you not following the new goal of low-density lipoprotein cholesterol < 55 mg/dL?


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