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Standardization Status of Total Cholesterol Concentration Measurement: Analysis of Korean External Quality Assessment Data

Yoon YA, Lee YW, Kim S, Lee K, Park HD, Chun S, Min WK

Background: Total cholesterol concentration measurement is important in the diagnosis of dyslipidemia and evaluation of cardiovascular disease risk factors. Measurement reliability for obtaining an accurate total cholesterol concentration requires procedure...
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Correlation between Serum Lipid Parameters and Interleukin-10 Concentration in Obese Individuals

Kim SJ, Lim J, Nam GE, Park HS

Background: The role of interleukin-10 (IL-10) in humans is controversial because IL-10 has been proposed to exhibit both pro- and anti-inflammatory effects. We aimed to determine the relationships between the...
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Relationship between Obesity and Dental Caries in Some University Students: A Pilot Study

Hwang S, Kim H, Seo M

Background: Obesity and dental caries have common risk factors such as food intake, eating habits, and lifestyle. Nevertheless, there has been no consensus on the significant association between obesity and...
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Maternal high-fructose intake during pregnancy and lactation induces metabolic syndrome in adult offspring

Koo S, Kim M, Cho HM, Kim I

BACKGROUND/OBJECTIVES: Nutritional status and food intake during pregnancy and lactation can affect fetal programming. In the current metabolic syndrome epidemic, highfructose diets have been strongly implicated. This study investigated the...
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The estimation of cholesterol intake in elderly: reliability and validity of short, Semi-Quantitative Food Frequency Questionnaire (SQ-FFQ)

Nindya TS, Mahmudiono T, Rachmah Q

Purpose: High intake of cholesterol leads to cardiovascular disruption. Estimating the actual intake of cholesterol can be beneficial for nutrition intervention. This research aimed to develop Semi-Quantitative Food Frequency Questionnaire...
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Pharmacotherapy for acute myocardial infarction

Kim SS, Kim HK

Clinical practice guidelines published by the European Society of Cardiology and the American College of Cardiology/ American Heart Association provide recommendations based on evidence, including randomized controlled trials and registry...
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Diabetes Fact Sheets in Korea, 2020: An Appraisal of Current Status

Jung CH, Son JW, Kang S, Kim WJ, Kim HS, Kim HS, Seo M, Shin HJ, Lee SS, Jeong SJ, Cho Y, Han SJ, Jang HM, Rho M, Lee S, Koo M, Yoo B, Moon JW, Lee HY, Yun JS, Kim SY, Kim SR, Jeong IK, Mok JO, Yoon KH

Background: This study aimed to investigate the recent prevalence, management, and comorbidities of diabetes among Korean adults aged ≥30 years by analyzing nationally representative data. Methods: This study used data from...
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High-Density Lipoprotein Cholesterol and the Risk of Myocardial Infarction, Stroke, and Cause-Specific Mortality: a Nationwide Cohort Study in Korea

Yang Y, Han K, Park SH, Kim MK, Yoon KH, Lee SH

Objective: We aimed to investigate the relationship between high-density lipoprotein cholesterol (HDL-C) level and the risk of myocardial infarction (MI), stroke, and causespecific mortality. Methods: Using the Korean National Health Insurance...
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Lactobacillus attenuates progression of nonalcoholic fatty liver disease by lowering cholesterol and steatosis

Lee NY, Shin MJ, Youn GS, Yoon SJ, Choi YR, Kim HS, Gupta H, Han SH, Kim BK, Lee DY, Park TS, Sung H, Kim BY, Suk KT

Background/Aims: Nonalcoholic fatty liver disease (NAFLD) is closely related to gut-microbiome. There is a paucity of research on which strains of gut microbiota affect the progression of NAFLD. This study...
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Lipid Profile Change after Thyroidectomy

Chu CH, Kim SY, Lee YS, Chang HS

Purpose: Thyroid diseases and lipid metabolic abnormalities have been reported to be correlated. In patients with thyroid cancer, thyroid stimulating hormone levels are suppressed to prevent recurrence. Many studies have...
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The Potential Role of Dyslipidemia in COVID-19 Severity: an Umbrella Review of Systematic Reviews

Choi GJ, Kim HM, Kang H

Objective: The aim of this study was to analyze the available knowledge about the potential association between dyslipidemia and the severity of coronavirus disease 2019 (COVID-19) as reported in previous...
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REvisiting Lipids in REtinal Diseases: A Focused Review on Age-related Macular Degeneration and Diabetic Retinopathy

Park SJ, Park DH

Dyslipidemia refers to an abnormal amount of lipid in the blood, and the total cholesterol level is defined as the sum of high-density lipoprotein cholesterol, low-density lipoprotein (LDL) cholesterol, and...
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Proprotein convertase subtilisin/kexin type 9 inhibition in cardiovascular disease: current status and future perspectives

Cho KH, Hong YJ

Proprotein convertase subtilisin/kexin type 9 (PCSK 9) targets the degradation of low-density lipoprotein (LDL) receptors; it has been proved that its inhibition improves cardiovascular outcomes in patients with established atherosclerotic...
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A Case of Temporal Bone Cholesterol Granuloma Extending to Posterior Cranial Fossa without Middle Ear Involvement

Ko MC, Jeong JY, Hwang SK, Yoo MH

Cholesterol granulomas of the temporal bone can occur in the petrous apex, middle ear, and mastoid cavity. Although cholesterol granulomas in the petrous apex often extend to the middle cranial...
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HDL Subclass Analysis in Predicting Metabolic Syndrome in Koreans With High HDL Cholesterol Levels

Yang HS, Hur M, Kim H, Kim SJ, Shin S, Di Somma S, on behalf of the GREAT Network

BACKGROUND: High-density lipoprotein cholesterol (HDL-C) is a complex mixture of subclasses with heterogeneous atheroprotective activities. We analyzed HDL-C subclass in relation to cardiovascular risk and metabolic syndrome (MetS) in a...
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Achievement of LDL-C Targets Defined by ESC/EAS (2011) Guidelines in Risk-Stratified Korean Patients with Dyslipidemia Receiving Lipid-Modifying Treatments

Yang YS, Lee SY, Kim JS, Choi KM, Lee KW, Lee SC, Cho JR, Oh SJ, Kim JH, Choi SH

Background: This study assessed the proportion of risk-stratified Korean patients with dyslipidemia achieving their low-density lipoprotein cholesterol (LDL-C) targets as defined by the European Society of Cardiology/European Atherosclerosis Society (ESC/EAS)...
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Effects of a Portfolio-Mediterranean Diet and a Mediterranean Diet with or without a Sterol-Enriched Yogurt in Individuals with Hypercholesterolemia

Ferro Y, Mazza E, Salvati M, Santariga E, Giampà S, Spagnuolo R, Doldo P, Pujia R, Coppola A, Gazzaruso C, Pujia A, Montalcini T

Background: A growing number of functional foods have been proposed to reduce cholesterol levels and the Portfolio Diet, which includes a combination of plant sterols, fibres, nuts, and soy protein,...
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Relationship between Serum Uric Acid Level and Low-Density Lipoprotein Cholesterol in Korea Adults: Korea National Health and Nutrition Examination Survey 2017

Lim S, Moon N

Background: Over the last few decades, the incidence of hyperuricemia has increased. Recently, the incidences of gout and asymptomatic hyperuricemia have been rapidly increasing in Korea. A correlation between serum...
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Metabolic Health, Obesity, and the Risk of Developing Open-Angle Glaucoma: Metabolically Healthy Obese Patients versus Metabolically Unhealthy but Normal Weight Patients

Jung Y, Han K, Park HYL, Lee SH, Park CK

BackgroundThis study sought to investigate the associations between metabolic health status, obesity, and incidence of primary open-angle glaucoma (POAG).MethodsIn this nationwide, population-based, longitudinal prospective cohort study conducted using the Korean...
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Oxysterol 25-hydroxycholesterol as a metabolic pathophysiological factors of osteoarthritis induces apoptosis in primary rat chondrocytes

Seo YS, Cho IA, Kim TH, You JS, Oh JS, Lee GJ, Kim DK, Kim JS

The aim of the present study was to investigate the pathophysiological etiology of osteoarthritis that is mediated by the apoptosis of chondrocytes exposed to 25-hydroxycholesterol (25-HC), an oxysterol synthesized by...
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