Nucl Med Mol Imaging.  2023 Aug;57(4):201-205. 10.1007/s13139-023-00792-8.

Breast Metastasis Arising from Ileal Neuroendocrine Tumor: an Unusual Presentation

Affiliations
  • 1Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
  • 2Department of Cytology and Gynaecological Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India

Abstract

Neuroendocrine tumors (NETs) up to 80% may have metastatic disease to lymph nodes, liver, and bones upon diagnosis due to their indolent course and benign nature. However, metastasis to the breast from gastropancreatic-neuroendocrine tumors (GEP-NETs) is unusual and rarely reported. Furthermore, such metastases may mimic a primary breast carcinoma clinically and radiologically. This case report illustrates an unusual presentation of metastasis to the right breast in addition to liver, pancreas, and lymph nodal metastases in a patient with ileal NET who was operated upon 5 years back. The metastases were detected by somatostatin receptor-based imaging and post-therapy scan which was confirmed by cytology and immunocytochemistry.

Keyword

Neuroendocrine tumor (NET); Ileal; Metastasis; 68Ga-DOTANOC PET/CT; 177Lu-DOTATATE therapy; PRRT; 18F-FDG PET/CT
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